WFRF:(Wahlström Jan)
Search: WFRF:(Wahlström Jan) > Analysis of three s...
- 26 of 100
- Previous record
- Next record
- To hitlist
Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q
-
- Enlund, Fredrik, 1968 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
-
- Samuelsson, Lena, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
-
- Enerbäck, Charlotta, 1965 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
- show more...
- show less...
- (creator_code:org_t)
- 1999
- 1999
- English.
- In: Hum Hered. ; 49:1, s. 2-8
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Psoriasis is known to be a heterogeneous disease with so far three reported major psoriasis susceptibility loci on chromosome 4q, 6p and 17q. In this study we investigated three reported gene locations by nonparametric and parametric linkage analysis in a large family set consisting of 104 families (153 sib pairs) from Sweden. We could confirm linkage to chromosome 6p. A maximum heterogeneous lod score of 2.78 was reached at locus D6S276 (alpha = 0.60). Allelic association studies within the HLA region indicated linkage disequilibrium at locus TNFbeta with a significant p value of 0.0009. Furthermore, we obtained weak evidence of linkage to the locus on chromosome 17q while no evidence of linkage could be found to the chromosome 4q region.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences (hsv//eng)
Keyword
- *Chromosomes
- Human
- Pair 17
- Chromosomes
- Human
- Pair 4
- *Chromosomes
- Human
- Pair 6
- Family Health
- *Genetic Predisposition to Disease
- HLA Antigens/*genetics
- Human
- Linkage (Genetics)/*genetics
- Linkage Disequilibrium
- Lod Score
- Psoriasis/*genetics
- Support
- Non-U.S. Gov't
- Sweden
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Analysis of three suggested psoriasis susceptibility loci in a large Swedish set... (Search for host publication in LIBRIS)
To the university's database
- 26 of 100
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Enlund, Fredrik, ...
- Samuelsson, Lena ...
- Enerbäck, Charlo ...
- Inerot, Annica, ...
- Wahlström, Jan, ...
- Yhr, Maria, 1968
- show more...
- Torinsson Naluai ...
- Martinsson, Tomm ...
- Swanbeck, Gunnar ...
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Other Medical an ...
- Articles in the publication
- Hum Hered
- By the university
- University of Gothenburg
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
