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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003333naa a2200325 4500
001oai:hhs.se:1162911140006056
003SwePub
008230928s2001 | |||||||||||000 ||eng|
024a https://research.hhs.se/esploro/outputs/journalArticle/The-burden-of-osteoporotic-fractures/9910015306981060562 URI
024a https://doi.org/10.1007/s0019801701122 DOI
040 a (SwePub)hhs
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Oden, Au Consulting Statistician4 aut
2451 0a The burden of osteoporotic fractures : A method for setting intervention thresholds
264 1b Springer,c 2001
520 a The aim of this study was to assess the relationship between morbidity from hip fracture and that from other osteoporotic fractures by age and sex based on the population of Sweden. Osteoporotic fractures were designated as those associated with low bone mineral density (BMD) and those that increased in incidence with age after the age of 50 years. Severity of fractures was weighted according to their morbidity using utility values based on those derived by the National Osteoporosis Foundation. Morbidity from fractures other than hip fracture was converted to hip fracture equivalents according to their disutility weights. Excess morbidity was 3.34 and 4.75 in men and women at the age of 50 years, i.e. the morbidity associated with osteoporotic fractures was 3-5 times that accounted for by hip fracture. Excess morbidity decreased with age to approximately 1.25 between the ages of 85 and 89 years. On the assumption that the age- and sex-specific pattern of fractures due to osteoporosis is similar in different communities, the computation of excess morbidity can be utilized to determine the total morbidity from osteoporotic fractures from knowledge of hip fracture rates alone. Such data can be used to weight probabilities of hip fracture in different countries in order to take into account the morbidity from fractures other than hip fracture, and to modify intervention thresholds based on hip fracture risk alone. If, for example, a 10-year probability of hip fracture of 10% was considered an intervention threshold, this would be exceeded in women with osteoporosis aged 65 years and more, but when weighted for other osteoporotic fractures would be exceeded in all women (and men) with osteoporosis.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng
700a Johnell, Ou Malmö University4 aut
700a DE LAET, Cu Institute for Medical Technology Assessment4 aut
700a Jönsson, Bengtu Stockholm School of Economics,Handelshögskolan i Stockholm4 aut0 (Swepub:hhs)211@hhs.se
700a Dawson, Au Lilly Research Centre Ltd4 aut
700a Kanis, J. Au University of Sheffield4 aut
710a Consulting Statisticianb Malmö University4 org
773t Osteoporosis internationald : Springerg 12:5, s. 417-427q 12:5<417-427x 1433-2965x 0937-941X
8564 8u https://research.hhs.se/esploro/outputs/journalArticle/The-burden-of-osteoporotic-fractures/991001530698106056
8564 8u https://doi.org/10.1007/s001980170112

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Oden, A
Johnell, O
DE LAET, C
Jönsson, Bengt
Dawson, A
Kanis, J. A
Om ämnet
MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Klinisk medicin
och Ortopedi
Artiklar i publikationen
Osteoporosis int ...
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Handelshögskolan i Stockholm

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