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Effectiveness of en...
Effectiveness of enamel matrix derivative on the clinical and microbiological outcomes following surgical regenerative treatment of peri-implantitis : A randomized controlled trial
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- Isehed, Catrine (författare)
- Umeå universitet,Uppsala universitet,Centrum för klinisk forskning, Gävleborg,Umea Univ, Dept Odontol Mol Periodontol, Umea, Sweden.; Gavle Cty Hosp, Dept Periodontol, Gavle, Sweden,Institutionen för odontologi,Department of Periodontology, Gävle County Hospital, Gävle, Sweden; Center for Research & Development, Uppsala University/Region Gävleborg, Gävle, Sweden,Umeå University
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- Holmlund, Anders (författare)
- Uppsala universitet,Centrum för klinisk forskning, Gävleborg,Gavle Cty Hosp, Dept Periodontol, Gavle, Sweden,Uppsala University
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- Renvert, Stefan (författare)
- Blekinge Tekniska Högskola,Institutionen för hälsa,Kristianstad Univ, Dept Hlth Sci, Kristianstad, Sweden.;Trinity Coll Dublin, Sch Dent Sci, Dublin, Ireland.;Blekinge Inst Technol, Karlskrona, Sweden.,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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- Svenson, Björn, 1941- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Oral Radiology, Postgraduate Dental Education Center, Örebro, Sweden,Postgraduate Dental Education Center Örebro, SWE,Postgrad Dent Educ Ctr, Dept Oral Radiol, Orebro, Sweden.;Univ Orebro, Sch Hlth & Med Sci, Fac Med & Hlth, Orebro, Sweden.,Örebro University
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- Johansson, Ingegerd (författare)
- Umeå universitet,Institutionen för odontologi,Umeå University
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- Lundberg, Pernilla (författare)
- Umeå universitet,Institutionen för odontologi,Umeå University
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(creator_code:org_t)
- 2016-07-15
- 2016
- Engelska.
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Ingår i: Journal of Clinical Periodontology. - Hoboken, USA : Wiley-Blackwell Publishing Inc.. - 0303-6979 .- 1600-051X. ; 43:10, s. 863-873
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objective: This randomized clinical trial aimed at comparing radiological, clinical and microbial effects of surgical treatment of peri-implantitis alone or in combination with enamel matrix derivative (EMD).Methods: Twenty-six subjects were treated with open flap debridement and decontamination of the implant surfaces with gauze and saline preceding adjunctive EMD or no EMD. Bone level (BL) change was primary outcome and secondary outcomes were changes in pocket depth (PD), plaque, pus, bleeding and the microbiota of the peri-implant biofilm analyzed by the Human Oral Microbe Identification Microarray over a time period of 12 months.Results: In multivariate modelling, increased marginal BL at implant site was significantly associated with EMD, the number of osseous walls in the peri-implant bone defect and a Gram+/aerobic microbial flora, whereas reduced BL was associated with a Gram-/anaerobic microbial flora and presence of bleeding and pus, with a cross-validated predictive capacity (Q(2) ) of 36.4%. Similar, but statistically non-significant, trends were seen for BL, PD, plaque, pus and bleeding in univariate analysis.Conclusion: Adjunctive EMD to surgical treatment of peri-implantitis was associated with prevalence of Gram+/aerobic bacteria during the follow-up period and increased marginal BL 12 months after treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- Bone level
- EMD treatment
- microbiota
- peri-implantitis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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