L773:0036 5548
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A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant
- Antonen, Jaakko (author)
- Leppanen, Ilona (author)
-
- Tenhunen, Jyrki (author)
- Uppsala universitet,Anestesiologi och intensivvård
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- Arvola, Pertti (author)
- Makela, Satu (author)
- Vaheri, Antti (author)
- Mustonen, Jukka (author)
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- (creator_code:org_t)
- 2013-01-07
- 2013
- English.
- In: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 45:6, s. 494-496
- Journal article (peer-reviewed)
Abstract
Subject headings
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- A patient with severe capillary leakage syndrome caused by a Puumala hantavirus infection was treated with a single dose of icatibant, a bradykinin receptor antagonist, with a dramatic positive response. We suggest that this drug should be tested in a larger number of patients with severe hantavirus infection.
Keyword
- Hantavirus
- bradykinin
- icatibant
- capillary leakage
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- ref (subject category)
- art (subject category)
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- Antonen, Jaakko
- Leppanen, Ilona
- Tenhunen, Jyrki
- Arvola, Pertti
- Makela, Satu
- Vaheri, Antti
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- Mustonen, Jukka
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