Osteoradionecrosis, an increasing indication for microvascular head and neck reconstruction

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Fältnamn	Indikatorer	Metadata
000		03163naa a2200421 4500
001		oai:DiVA.org:su-179693
003		SwePub
008		200305s2020 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:prod.swepub.kib.ki.se:142854237
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1796932 URI
024	7	a https://doi.org/10.1016/j.ijom.2019.06.0092 DOI
024	7	a http://kipublications.ki.se/Default.aspx?queryparsed=id:1428542372 URI
040		a (SwePub)sud (SwePub)ki
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Danielsson, D.u Karolinska Institutet4 aut
245	1 0	a Osteoradionecrosis, an increasing indication for microvascular head and neck reconstruction
264	1	b Elsevier BV,c 2020
338		a print2 rdacarrier
520		a Better cancer treatment has led to a steadily growing population of cancer survivors suffering from late adverse effects after cancer treatment. The aim of this study was to investigate whether there has been an increase in free flap reconstruction due to osteoradionecrosis (ORN). A retrospective review was conducted to identify all consecutive head and neck free flap reconstructions performed over an 18-year period (1995-2012) at Karolinska University Hospital. A total of 235 free flaps were identified. Cases were divided into two groups: head and neck cancer reconstructions and ORN reconstructions. A comparison between the two groups showed longer survival (P < 0.001) and higher rates of late complications (P < 0.001) among ORN cases. ORN as an indication for reconstruction increased over time, from 7.0% of the total number of free flaps performed in 1995-2000, to 15.2% during the period 2001-2006, and to 27.3% in 2007-2012 (P < 0.001). This, in accordance with the results of other studies, highlights the importance of the appropriate allocation of resources within the healthcare system to treat this patient group within the steadily increasing population of cancer survivors.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653		a ORN
653		a osteoradionecrosis
653		a free flap
653		a head and neck
653		a microvascular reconstruction
700	1	a Gahm, C.4 aut
700	1	a Haghdoost, Siamaku Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut,University of Caen Normandy, France4 aut0 (Swepub:su)shagh
700	1	a Munck-Wikland, E.u Karolinska Institutet4 aut
700	1	a Halle, M.u Karolinska Institutet4 aut
710	2	a Karolinska Institutetb Institutionen för molekylär biovetenskap, Wenner-Grens institut4 org
773	0	t International Journal of Oral and Maxillofacial Surgeryd : Elsevier BVg 49:1, s. 1-6q 49:1<1-6x 0901-5027x 1399-0020
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-179693
856	4 8	u https://doi.org/10.1016/j.ijom.2019.06.009
856	4 8	u http://kipublications.ki.se/Default.aspx?queryparsed=id:142854237

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International Journal of Oral and Maxillofacial Surgery (Sök värdpublikationen i LIBRIS)

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Av författaren/redakt...: Danielsson, D.; Gahm, C.; Haghdoost, Siama ...; Munck-Wikland, E ...; Halle, M.

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kirurgi

Artiklar i publikationen: International Jo ...

Av lärosätet: Stockholms universitet; Karolinska Institutet

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