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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003655naa a2200385 4500
001oai:lup.lub.lu.se:7287814e-434d-4886-9ddd-b3d3ef4294c7
003SwePub
008160401s2015 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/52649792 URI
0247 a https://doi.org/10.1016/j.pscychresns.2015.02.0012 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Power, Brian D4 aut
2451 0a Validation of a protocol for manual segmentation of the thalamus on magnetic resonance imaging scans.
264 1b Elsevier BV,c 2015
520 a We present a validated protocol for manual segmentation of the thalamus on T1-weighted magnetic resonance imaging (MRI) scans using brain image analysis software. The MRI scans of five normal control subjects were randomly selected from a larger cohort recruited from Lund University Hospital and Landskrona Hospital, Sweden. MRIs were performed using a 3.0T Philips MR scanner, with an eight-channel head coil, and high resolution images were acquired using a T1-weighted turbo field echo (T1 TFE) pulse sequence, with resulting voxel size 1×1×1mm(3). Manual segmentation of the left and right thalami and volume measurement was performed on 28-30 contiguous coronal slices, using ANALYZE 11.0 software. Reliability of image analysis was performed by measuring intra-class correlations between initial segmentation and random repeated segmentation of the left and right thalami (in total 10 thalami for segmentation); inter-rater reliability was measured using volumes obtained by two other experienced tracers. Intra-class correlations for two independent raters were 0.95 and 0.98; inter-class correlations between the expert rater and two independent raters were 0.92 and 0.98. We anticipate that mapping thalamic morphology in various neuropsychiatric disorders may yield clinically useful disease-specific biomarkers.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
7001 a Wilkes, Fiona A4 aut
7001 a Hunter-Dickson, Mitchell4 aut
7001 a van Westen, Danielleu Lund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neuroradiologi,Forskargrupper vid Lunds universitet,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Neuroradiology,Lund University Research Groups4 aut0 (Swepub:lu)ront-dva
7001 a Santillo, Alexanderu Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups4 aut0 (Swepub:lu)med-ast
7001 a Walterfang, Mark4 aut
7001 a Nilsson, Christeru Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups4 aut0 (Swepub:lu)neur-cni
7001 a Velakoulis, Dennis4 aut
7001 a Looi, Jeffrey C L4 aut
7102 a Diagnostisk radiologi, Lundb Sektion V4 org
7730 t Psychiatry Researchd : Elsevier BVg 232:1, s. 98-105q 232:1<98-105x 1872-7123x 0925-4927
8564 u http://www.ncbi.nlm.nih.gov/pubmed/25752844?dopt=Abstracty FULLTEXT
8564 u http://dx.doi.org/10.1016/j.pscychresns.2015.02.001y FULLTEXT
8564 8u https://lup.lub.lu.se/record/5264979
8564 8u https://doi.org/10.1016/j.pscychresns.2015.02.001

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