Sökning: WFRF:(Lundin Stefan 1953) >
Validation and clin...
Validation and clinical feasibility of nitrogen washin/washout functional residual capacity measurements in children.
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- Olegård, Cecilia, 1967 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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- Söndergaard, Sören, 1951 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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- Pålsson, Jan, 1955 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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- Lundin, Stefan, 1953 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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- Stenqvist, Ola, 1944 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för anestesiologi och intensivvård,Institute of Clinical Sciences, Department of Anesthesiology and Intensive care
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(creator_code:org_t)
- Wiley, 2010
- 2010
- Engelska.
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Ingår i: Acta anaesthesiologica Scandinavica. - : Wiley. - 1399-6576 .- 0001-5172. ; 54:3, s. 370-6
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The functional residual capacity (FRC) is an important parameter in pediatric respiratory monitoring but it is difficult to assess in the clinical setting. We have introduced a modified N(2) washout method utilizing a change of F(I)O(2) of 0.1 for FRC measurement in adult respiratory monitoring. This study validated the algorithm in a pediatric lung model and investigated the stability and feasibility in a pediatric peri-operative and intensive care setting. METHODS: The lung model was ventilated in combinations of ventilatory modes, CO(2) production, model FRC and respiratory rates. Sixteen children from 10 days to 5 years were studied peri-operatively with controlled ventilation using a Mapleson D system and in the intensive care unit using a Servo-i ventilator in a supported spontaneous mode. FRC was measured during stable metabolic, respiratory and circulatory periods at positive end expiratory pressure of 3-4 and 7-8 cmH(2)O. RESULTS: In the model and in the clinical setting, we found an excellent agreement between washout and washin measurements of FRC as well as acceptable coefficients of repeatability. CONCLUSION: FRC was satisfactorily measured by a modified N(2) algorithm and may be included as a monitoring variable in pediatric respiratory care. Pediatric FRC monitoring demands strictly stable conditions as measurements are performed close to the limits of the monitor's specifications.
Nyckelord
- Algorithms
- Anesthesia
- General
- Blood Gas Analysis
- Carbon Dioxide
- blood
- Child
- Feasibility Studies
- Female
- Functional Residual Capacity
- physiology
- Humans
- Intensive Care
- Male
- Models
- Anatomic
- Nitrogen
- analysis
- metabolism
- Positive-Pressure Respiration
- Reproducibility of Results
- Respiration
- Artificial
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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