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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06711naa a2201549 4500 | |
| 001 | oai:DiVA.org:uu-151963 | |
| 003 | SwePub | |
| 008 | 110420s2011 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:122295668 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1519632 URI |
| 024 | 7 | a https://doi.org/10.1038/ng.7822 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1222956682 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Peden, John F.4 aut |
| 245 | 1 0 | a A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease |
| 264 | c 2011-03-06 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2011 |
| 338 | a print2 rdacarrier | |
| 520 | a Genome-wide association studies have identified 11 common variants convincingly associated with coronary artery disease (CAD)(1-7), a modest number considering the apparent heritability of CAD(8). All of these variants have been discovered in European populations. We report a meta-analysis of four large genome-wide association studies of CAD, with similar to 575,000 genotyped SNPs in a discovery dataset comprising 15,420 individuals with CAD (cases) (8,424 Europeans and 6,996 South Asians) and 15,062 controls. There was little evidence for ancestry-specific associations, supporting the use of combined analyses. Replication in an independent sample of 21,408 cases and 19,185 controls identified five loci newly associated with CAD (P < 5 x 10(-8) in the combined discovery and replication analysis): LIPA on 10q23, PDGFD on 11q22, ADAMTS7-MORF4L1 on 15q25, a gene rich locus on 7q22 and KIAA1462 on 10p11. The CAD-associated SNP in the PDGFD locus showed tissue-specific cis expression quantitative trait locus effects. These findings implicate new pathways for CAD susceptibility. | |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 700 | 1 | a Hopewell, Jemma C.4 aut |
| 700 | 1 | a Saleheen, Danish4 aut |
| 700 | 1 | a Chambers, John C.4 aut |
| 700 | 1 | a Hager, Jorg4 aut |
| 700 | 1 | a Soranzo, Nicole4 aut |
| 700 | 1 | a Collins, Rory4 aut |
| 700 | 1 | a Danesh, John4 aut |
| 700 | 1 | a Elliott, Paul4 aut |
| 700 | 1 | a Farrall, Martinu Karolinska Institutet4 aut |
| 700 | 1 | a Stirrups, Kathy4 aut |
| 700 | 1 | a Zhang, Weihua4 aut |
| 700 | 1 | a Hamsten, Andersu Karolinska Institutet4 aut |
| 700 | 1 | a Parish, Sarah4 aut |
| 700 | 1 | a Lathrop, Marku Karolinska Institutet4 aut |
| 700 | 1 | a Watkins, Hugh4 aut |
| 700 | 1 | a Clarke, Robert4 aut |
| 700 | 1 | a Deloukas, Panos4 aut |
| 700 | 1 | a Kooner, Jaspal S.4 aut |
| 700 | 1 | a Goel, Anuj4 aut |
| 700 | 1 | a Ongen, Halit4 aut |
| 700 | 1 | a Strawbridge, Rona J.u Karolinska Institutet4 aut |
| 700 | 1 | a Heath, Simon4 aut |
| 700 | 1 | a Mälarstig, Andersu Karolinska Institutet4 aut |
| 700 | 1 | a Helgadottir, Anna4 aut |
| 700 | 1 | a Öhrvik, Johnu Karolinska Institutet4 aut |
| 700 | 1 | a Murtaza, Muhammed4 aut |
| 700 | 1 | a Potter, Simon4 aut |
| 700 | 1 | a Hunt, Sarah E.4 aut |
| 700 | 1 | a Delepine, Marc4 aut |
| 700 | 1 | a Jalilzadeh, Shapour4 aut |
| 700 | 1 | a Axelsson, Tomasu Uppsala universitet,Molekylär medicin4 aut0 (Swepub:uu)toaxe957 |
| 700 | 1 | a Syvänen, Ann-Christineu Uppsala universitet,Molekylär medicin4 aut0 (Swepub:uu)anncsyva |
| 700 | 1 | a Gwilliam, Rhian4 aut |
| 700 | 1 | a Bumpstead, Suzannah4 aut |
| 700 | 1 | a Gray, Emma4 aut |
| 700 | 1 | a Edkins, Sarah4 aut |
| 700 | 1 | a Folkersen, Lasseu Karolinska Institutet4 aut |
| 700 | 1 | a Kyriakou, Theodosios4 aut |
| 700 | 1 | a Franco-Cereceda, Andersu Karolinska Institutet4 aut |
| 700 | 1 | a Gabrielsen, Andersu Karolinska Institutet4 aut |
| 700 | 1 | a Seedorf, Udo4 aut |
| 700 | 1 | a Eriksson, Peru Karolinska Institutet4 aut |
| 700 | 1 | a Offer, Alison4 aut |
| 700 | 1 | a Bowman, Louise4 aut |
| 700 | 1 | a Sleight, Peter4 aut |
| 700 | 1 | a Armitage, Jane4 aut |
| 700 | 1 | a Peto, Richard4 aut |
| 700 | 1 | a Abecasis, Goncalo4 aut |
| 700 | 1 | a Ahmed, Nabeel4 aut |
| 700 | 1 | a Caulfield, Mark4 aut |
| 700 | 1 | a Donnelly, Peter4 aut |
| 700 | 1 | a Froguel, Philippe4 aut |
| 700 | 1 | a Kooner, Angad S.u Karolinska Institutet4 aut |
| 700 | 1 | a McCarthy, Mark I.4 aut |
| 700 | 1 | a Samani, Nilesh J.4 aut |
| 700 | 1 | a Scott, James4 aut |
| 700 | 1 | a Sehmi, Joban4 aut |
| 700 | 1 | a Silveira, Angela4 aut |
| 700 | 1 | a Hellenius, Mai-Lis4 aut |
| 700 | 1 | a van't Hooft, Ferdinand M.4 aut |
| 700 | 1 | a Olsson, Gunnar4 aut |
| 700 | 1 | a Rust, Stephan4 aut |
| 700 | 1 | a Assmann, Gerd4 aut |
| 700 | 1 | a Barlera, Simona4 aut |
| 700 | 1 | a Tognoni, Gianni4 aut |
| 700 | 1 | a Franzosi, Maria Grazia4 aut |
| 700 | 1 | a Linksted, Pamela4 aut |
| 700 | 1 | a Green, Fiona R.4 aut |
| 700 | 1 | a Rasheed, Asif4 aut |
| 700 | 1 | a Zaidi, Moazzam4 aut |
| 700 | 1 | a Shah, Nabi4 aut |
| 700 | 1 | a Samuel, Maria4 aut |
| 700 | 1 | a Mallick, Nadeem H.4 aut |
| 700 | 1 | a Azhar, Muhammad4 aut |
| 700 | 1 | a Zaman, Khan S.4 aut |
| 700 | 1 | a Samad, Abdus4 aut |
| 700 | 1 | a Ishaq, Mohammad4 aut |
| 700 | 1 | a Gardezi, Ali R.4 aut |
| 700 | 1 | a Memon, Fazal-ur-Rehman4 aut |
| 700 | 1 | a Frossard, Philippe M.4 aut |
| 700 | 1 | a Spector, Tim4 aut |
| 700 | 1 | a Peltonen, Leena4 aut |
| 700 | 1 | a Nieminen, Markku S.4 aut |
| 700 | 1 | a Sinisalo, Juha4 aut |
| 700 | 1 | a Salomaa, Veikko4 aut |
| 700 | 1 | a Ripatti, Samuli4 aut |
| 700 | 1 | a Bennett, Derrick4 aut |
| 700 | 1 | a Leander, Karinu Karolinska Institutet4 aut |
| 700 | 1 | a Gigante, Brunau Karolinska Institutet4 aut |
| 700 | 1 | a de Faire, Ulfu Karolinska Institutet4 aut |
| 700 | 1 | a Pietri, Silvia4 aut |
| 700 | 1 | a Gori, Francesca4 aut |
| 700 | 1 | a Marchioli, Roberto4 aut |
| 700 | 1 | a Sivapalaratnam, Suthesh4 aut |
| 700 | 1 | a Kastelein, John J. P.4 aut |
| 700 | 1 | a Trip, Mieke D.4 aut |
| 700 | 1 | a Theodoraki, Eirini V.4 aut |
| 700 | 1 | a Dedoussis, George V.4 aut |
| 700 | 1 | a Engert, Jamie C.4 aut |
| 700 | 1 | a Yusuf, Salim4 aut |
| 700 | 1 | a Anand, Sonia S.4 aut |
| 710 | 2 | a Karolinska Institutetb Molekylär medicin4 org |
| 773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 43:4, s. 339-344q 43:4<339-344x 1061-4036x 1546-1718 |
| 856 | 4 | u https://www.openaccessrepository.it/record/22004/files/fulltext.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-151963 |
| 856 | 4 8 | u https://doi.org/10.1038/ng.782 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:122295668 |
Hitta mer i SwePub
- Av författaren/redakt...
- Peden, John F.
- Hopewell, Jemma ...
- Saleheen, Danish
- Chambers, John C ...
- Hager, Jorg
- Soranzo, Nicole
- visa fler...
- Collins, Rory
- Danesh, John
- Elliott, Paul
- Farrall, Martin
- Stirrups, Kathy
- Zhang, Weihua
- Hamsten, Anders
- Parish, Sarah
- Lathrop, Mark
- Watkins, Hugh
- Clarke, Robert
- Deloukas, Panos
- Kooner, Jaspal S ...
- Goel, Anuj
- Ongen, Halit
- Strawbridge, Ron ...
- Heath, Simon
- Mälarstig, Ander ...
- Helgadottir, Ann ...
- Öhrvik, John
- Murtaza, Muhamme ...
- Potter, Simon
- Hunt, Sarah E.
- Delepine, Marc
- Jalilzadeh, Shap ...
- Axelsson, Tomas
- Syvänen, Ann-Chr ...
- Gwilliam, Rhian
- Bumpstead, Suzan ...
- Gray, Emma
- Edkins, Sarah
- Folkersen, Lasse
- Kyriakou, Theodo ...
- Franco-Cereceda, ...
- Gabrielsen, Ande ...
- Seedorf, Udo
- Eriksson, Per
- Offer, Alison
- Bowman, Louise
- Sleight, Peter
- Armitage, Jane
- Peto, Richard
- Abecasis, Goncal ...
- Ahmed, Nabeel
- Caulfield, Mark
- Donnelly, Peter
- Froguel, Philipp ...
- Kooner, Angad S.
- McCarthy, Mark I ...
- Samani, Nilesh J ...
- Scott, James
- Sehmi, Joban
- Silveira, Angela
- Hellenius, Mai-L ...
- van't Hooft, Fer ...
- Olsson, Gunnar
- Rust, Stephan
- Assmann, Gerd
- Barlera, Simona
- Tognoni, Gianni
- Franzosi, Maria ...
- Linksted, Pamela
- Green, Fiona R.
- Rasheed, Asif
- Zaidi, Moazzam
- Shah, Nabi
- Samuel, Maria
- Mallick, Nadeem ...
- Azhar, Muhammad
- Zaman, Khan S.
- Samad, Abdus
- Ishaq, Mohammad
- Gardezi, Ali R.
- Memon, Fazal-ur- ...
- Frossard, Philip ...
- Spector, Tim
- Peltonen, Leena
- Nieminen, Markku ...
- Sinisalo, Juha
- Salomaa, Veikko
- Ripatti, Samuli
- Bennett, Derrick
- Leander, Karin
- Gigante, Bruna
- de Faire, Ulf
- Pietri, Silvia
- Gori, Francesca
- Marchioli, Rober ...
- Sivapalaratnam, ...
- Kastelein, John ...
- Trip, Mieke D.
- Theodoraki, Eiri ...
- Dedoussis, Georg ...
- Engert, Jamie C.
- Yusuf, Salim
- Anand, Sonia S.
- visa färre...
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- Uppsala universitet
- Karolinska Institutet
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