Sökning: WFRF:(Badiu I.) > ESE audit on manage...
Fältnamn | Indikatorer | Metadata |
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000 | 05283naa a2200901 4500 | |
001 | oai:gup.ub.gu.se/299505 | |
003 | SwePub | |
008 | 240528s2021 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:145755281 | |
024 | 7 | a https://gup.ub.gu.se/publication/2995052 URI |
024 | 7 | a https://doi.org/10.1530/EJE-20-11802 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1457552812 URI |
040 | a (SwePub)gud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Martel-Duguech, Luciana Maria4 aut |
245 | 1 0 | a ESE audit on management of Adult Growth Hormone Deficiency in clinical practice. |
264 | 1 | c 2021 |
520 | a Guidelines recommend adults with pituitary disease in whom GH therapy is contemplated, to be tested for GH deficiency (AGHD); however, clinical practice is not uniform.1) To record current practice of AGHD management throughout Europe and benchmark it against guidelines; 2) To evaluate educational status of healthcare professionals about AGHD.On-line survey in endocrine centres throughout Europe.Endocrinologists voluntarily completed an electronic questionnaire regarding AGHD patients diagnosed or treated in 2017-2018.Twenty-eight centres from 17 European countries participated, including 2139 AGHD patients, 28% of childhood-onset GHD. Aetiology was most frequently non-functioning pituitary adenoma (26%), craniopharyngioma (13%) and genetic/congenital mid-line malformations (13%). Diagnosis of GHD was confirmed by a stimulation test in 52% (GHRH+arginine, 45%; insulin-tolerance, 42%, glucagon, 6%; GHRH alone and clonidine tests, 7%); in the remaining, ≥3 pituitary deficiencies and low serum IGF-I were diagnostic. Initial GH dose was lower in older patients, but only women <26 years were prescribed a higher dose than men; dose titration was based on normal serum IGF-I, tolerance and side-effects. In one country, AGHD treatment was not approved. Full public reimbursement was not available in four countries and only in childhood-onset GHD in another. AGHD awareness was low among non-endocrine professionals and healthcare administrators. Postgraduate AGHD curriculum training deserves being improved.Despite guideline recommendations, GH replacement in AGHD is still not available or reimbursed in all European countries. Knowledge among professionals and health administrators needs improvement to optimize care of adults with GHD. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
700 | 1 | a Jorgensen, Jens Otto L4 aut |
700 | 1 | a Korbonits, Marta4 aut |
700 | 1 | a Johannsson, Gudmundur,d 1960u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xjgudn |
700 | 1 | a Webb, Susan M4 aut |
700 | 1 | a Amadidou, Fotini4 aut |
700 | 1 | a Mintziori, G4 aut |
700 | 1 | a Arosio, Maura4 aut |
700 | 1 | a Giavoli, Claudia4 aut |
700 | 1 | a Badiu, Corin4 aut |
700 | 1 | a Boschetti, Mara4 aut |
700 | 1 | a Ferone, Diego4 aut |
700 | 1 | a Ricci Bitti, Silvia4 aut |
700 | 1 | a Brue, Thierry4 aut |
700 | 1 | a Albarel, F4 aut |
700 | 1 | a Cannavò, Salvatore4 aut |
700 | 1 | a Cotta, Oana Ruxandra4 aut |
700 | 1 | a Carvalho, Davide4 aut |
700 | 1 | a Salazar, Daniela4 aut |
700 | 1 | a Christ, Emanuel4 aut |
700 | 1 | a Debono, Miguel4 aut |
700 | 1 | a Dusek, Tina4 aut |
700 | 1 | a Garcia-Centeno, Rogelio4 aut |
700 | 1 | a Ghigo, Ezio4 aut |
700 | 1 | a Gasco, Valentina4 aut |
700 | 1 | a Góth, Miklós I4 aut |
700 | 1 | a Oláh, Dóra4 aut |
700 | 1 | a Kovacs, Laszlo4 aut |
700 | 1 | a Höybye, Charlotte4 aut |
700 | 1 | a Kocjan, Tomaz4 aut |
700 | 1 | a Mlekuš Kozamernik, Katarina4 aut |
700 | 1 | a Kužma, Martin4 aut |
700 | 1 | a Payer, Juraj4 aut |
700 | 1 | a Medic-Stojanoska, Milica4 aut |
700 | 1 | a Novak, Anela4 aut |
700 | 1 | a Miličević, Tanja4 aut |
700 | 1 | a Pekic, Sandra4 aut |
700 | 1 | a Miljic, Dragana4 aut |
700 | 1 | a Perez Luis, Jesus4 aut |
700 | 1 | a Pico, Antonio M4 aut |
700 | 1 | a Preda, Veronica4 aut |
700 | 1 | a Raverot, Gerald4 aut |
700 | 1 | a Borson-Chazot, Francoise4 aut |
700 | 1 | a Rochira, Vincenzo4 aut |
700 | 1 | a Monzani, María Laura4 aut |
700 | 1 | a Sandahl, Kristian4 aut |
700 | 1 | a Tsagarakis, Stylianos4 aut |
700 | 1 | a Mitravela, Vana4 aut |
700 | 1 | a Zacharieva, Sabina4 aut |
700 | 1 | a Zilaitiene, Birute4 aut |
700 | 1 | a Verkauskiene, Rasa4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition4 org |
773 | 0 | t European journal of endocrinologyg 184:2, s. 323-334q 184:2<323-334x 1479-683X |
856 | 4 8 | u https://gup.ub.gu.se/publication/299505 |
856 | 4 8 | u https://doi.org/10.1530/EJE-20-1180 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145755281 |
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