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Digital Examination...
Digital Examination of LYmph node CYtopathology Using the Sydney system (DELYCYUS). An international, multi-institutional study
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- Caputo, Alessandro (författare)
- University Hospital of Salerno
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- Fraggetta, Filippo (författare)
- Gravina and Santo Pietro Hospital
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- Cretella, Pasquale (författare)
- University of Naples Federico II
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- Cozzolino, Immacolata (författare)
- University of Campania Luigi Vanvitelli
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- Eccher, Albino (författare)
- University Hospital Verona
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- Girolami, Ilaria (författare)
- Provincial Hospital of Bolzano
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Marletta, Stefano (författare)
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- Troncone, Giancarlo (författare)
- University of Naples Federico II
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- Vigliar, Elena (författare)
- University of Naples Federico II
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- Acanfora, Gennaro (författare)
- University of Naples Federico II
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Zarra, Karen Villar (författare)
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- Torres Rivas, Héctor Enrique (författare)
- Asturias General Hospital
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- Fadda, Guido (författare)
- University of Messina
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- Field, Andrew (författare)
- University of New South Wales
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- Katz, Ruth (författare)
- Sheba Medical Center
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- Vielh, Philippe (författare)
- The American Hospital of Paris
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- Eloy, Catarina (författare)
- University of Porto
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- Rajwanshi, Arvind (författare)
- Ministry of Health and Family Welfare, India
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- Gupta, Nalini (författare)
- Postgraduate Institute of Medical Education and Research
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- Al-Abbadi, Mousa (författare)
- University of Jordan
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- Bustami, Nadwa (författare)
- University of Jordan
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- Arar, Tala (författare)
- University of Jordan
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- Calaminici, Maria (författare)
- Queen Mary University
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Raine, Juliet I. (författare)
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- Barroca, Helena (författare)
- Sao Joao Hospital
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- Canão, Pedro Amoroso (författare)
- Sao Joao Hospital
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- Ehinger, Mats (författare)
- Lund University,Lunds universitet,Patologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pathology, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Rajabian, Nilofar (författare)
- Lund University,Lunds universitet,Patologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Pathology, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Dey, Pranab (författare)
- Postgraduate Institute of Medical Education and Research
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- Medeiros, L. Jeffrey (författare)
- University of Texas
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- El Hussein, Siba (författare)
- University of Rochester Medical Center
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- Lin, Oscar (författare)
- Memorial Sloan-Kettering Cancer Center
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D’Antonio, Antonio (författare)
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- Bode-Lesniewska, Beata (författare)
- Pathologie Institut Enge
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- Rossi, Esther Diana (författare)
- Catholic University of the Sacred Heart, Rome
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- Zeppa, Pio (författare)
- University Hospital of Salerno
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(creator_code:org_t)
- 2023
- 2023
- Engelska.
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Ingår i: Cancer Cytopathology. - 1934-662X. ; 131:11, s. 679-692
- Relaterad länk:
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http://dx.doi.org/10... (free)
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visa fler...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: After a series of standardized reporting systems in cytopathology, the Sydney system was recently introduced to address the need for reproducibility and standardization in lymph node cytopathology. Since then, the risk of malignancy for the categories of the Sydney system has been explored by several studies, but no studies have yet examined the interobserver reproducibility of the Sydney system. Methods: The authors assessed interobserver reproducibility of the Sydney system on 85 lymph node fine-needle aspiration cytology cases reviewed by 15 cytopathologists from 12 institutions in eight different countries, resulting in 1275 diagnoses. In total, 186 slides stained with Diff-Quik, Papanicolaou, and immunocytochemistry were scanned. A subset of the cases included clinical data and results from ultrasound examinations, flow cytometry immunophenotyping, and fluorescence in situ hybridization analysis. The study participants assessed the cases digitally using whole-slide images. Results: Overall, the authors observed an almost perfect agreement of cytopathologists with the ground truth (median weighted Cohen κ = 0.887; interquartile range, κ = 0.210) and moderate overall interobserver concordance (Fleiss κ = 0.476). There was substantial agreement for the inadequate and malignant categories (κ = 0.794 and κ = 0.729, respectively), moderate agreement for the benign category (κ = 0.490), and very slight agreement for the suspicious (κ = 0.104) and atypical (κ = 0.075) categories. Conclusions: The Sydney system for reporting lymph node cytopathology shows adequate interobserver concordance. Digital microscopy is an adequate means to assess lymph node cytopathology specimens.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- digital cytopathology
- lymph node
- reproducibility
- virtual microscopy
- whole-slide imaging
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Caputo, Alessand ...
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Fraggetta, Filip ...
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Cretella, Pasqua ...
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Cozzolino, Immac ...
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Eccher, Albino
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Girolami, Ilaria
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Marletta, Stefan ...
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Troncone, Gianca ...
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Vigliar, Elena
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Acanfora, Gennar ...
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Zarra, Karen Vil ...
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Torres Rivas, Hé ...
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Fadda, Guido
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Field, Andrew
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Katz, Ruth
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Vielh, Philippe
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Eloy, Catarina
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Rajwanshi, Arvin ...
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Gupta, Nalini
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Al-Abbadi, Mousa
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Bustami, Nadwa
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Arar, Tala
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Calaminici, Mari ...
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Raine, Juliet I.
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Barroca, Helena
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Canão, Pedro Amo ...
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Ehinger, Mats
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Rajabian, Nilofa ...
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Dey, Pranab
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Medeiros, L. Jef ...
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El Hussein, Siba
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Lin, Oscar
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D’Antonio, Anton ...
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Bode-Lesniewska, ...
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Rossi, Esther Di ...
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Zeppa, Pio
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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Cancer Cytopatho ...
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Lunds universitet