A conversational robotic lab assistant for automated microfluidic 3d microtissue production

QC 20210330
The future of life science is linked to automation and microfluidics. Here we present a robotic lab assistant, a general automation platform for droplet microfluidics including a conversational mobile interface. We demonstrate the automated production of human cancer microtissues in droplets at a throughput of 85000 spheroids per microfluidic circuit per hour. The capability of automated spheroid generation is directly applicable to precision medicine and drug screening. Multiple cell lines were successfully tested, including cancer cell lines, co-cultures, and primary cells. The 3D-microtissues/spheroids were automatically assembled-incubated-retrieved with high viability for further drug screening analysis - the platform interfaces with standard labware.

MEDICIN OCH HÄLSOVETENSKAP Medicinsk bioteknologi hsv//swe
MEDICAL AND HEALTH SCIENCES Medical Biotechnology hsv//eng
TEKNIK OCH TEKNOLOGIER Industriell bioteknik Läkemedelsbioteknik hsv//swe
ENGINEERING AND TECHNOLOGY Industrial Biotechnology Pharmaceutical Biotechnology hsv//eng
NATURVETENSKAP Biologi Biokemi och molekylärbiologi hsv//swe
NATURAL SCIENCES Biological Sciences Biochemistry and Molecular Biology hsv//eng
3D-microtissues
Automation of droplet microfluidics
Drug screening
Robotic lab assistant
Cell culture
Diagnosis
Diseases
Drops
Robotics
Throughput
Automated productions
Cancer cell lines
Droplet microfluidics
Microfluidic circuit
Mobile interface
Multiple cells
Platform interface
Microfluidics

Ingår i:23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019: Chemical and Biological Microsystems Society, s. 888-889

Av författaren/redakt...: Langer, Krzyszto ...; Jernström, Sandr ...; Mikkonen, Piia; Östling, Päiivi; Seashore-Ludlow, ...; Jönsson, Håkan, ...

Om ämnet

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Industriell biot ...; och Läkemedelsbiotek ...

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