Sökning: WFRF:(Laura C) > (1998-1999) > Nerve growth factor...
Fältnamn | Indikatorer | Metadata |
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000 | 03905naa a2200481 4500 | |
001 | oai:DiVA.org:liu-168014 | |
003 | SwePub | |
008 | 200811s1998 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:1937761 | |
009 | oai:DiVA.org:uu-56668 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1680142 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19377612 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-566682 URI |
040 | a (SwePub)liud (SwePub)kid (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Frisen, Ju Karolinska Institutet4 aut |
245 | 1 0 | a Nerve growth factor induces process formation in meningeal cells :b Implications for scar formation in the injured CNS |
264 | 1 | a Karolinska Inst, Dept Neurosci, S-17177 Stockholm, Sweden. Karolinska Inst, Dept Cell & Mol Biol, Med Nobel Inst, S-17177 Stockholm, Sweden. Biomed Ctr, Dept Dev Neurosci, S-75123 Uppsala, Sweden. McGill Univ, Montreal Neurol Inst, Brain Tumor Res Ctr, Montreal, PQ H3A 2B4, Canada.b SOC NEUROSCIENCE,c 1998 |
338 | a print2 rdacarrier | |
520 | a Nerve growth factor (NGF) induces the differentiation and supports the survival of subpopulations of neurons in the PNS and CNS. Here we report that meningeal cells in the pia mater express immunoreactivity and mRNA for both known NGF receptors, the low-affinity receptor p75 and the tyrosine kinase receptor trkA. NGF induces rapid tyrosine phosphorylation of trkA in meningeal cells in vitro. NGF does not stimulate proliferation of primary meningeal cells but induces process outgrowth. p75- and trkA-immunoreactive meningeal cells with long processes, resembling NGF-treated cells in vitro, are abundant in the scar tissue that forms at spinal cord lesions in rat and cat. These data suggest that NGF, which is expressed at increased levels in the brain and spinal cord after lesions, may be involved in scar formation in the injured CNS. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
653 | a NGF | |
653 | a trkA | |
653 | a p75 | |
653 | a injury | |
653 | a regeneration | |
653 | a meningeal cells | |
700 | 1 | a Risling, Mu Karolinska Institutet4 aut |
700 | 1 | a Korhonen, Laurau Uppsala universitet,Institutionen för neurovetenskap4 aut0 (Swepub:liu)lauko83 |
700 | 1 | a Zirrgiebel, U4 aut |
700 | 1 | a Johansson, C Bu Karolinska Institutet4 aut |
700 | 1 | a Cullheim, Su Karolinska Institutet4 aut |
700 | 1 | a Lindholm, Du Uppsala universitet,Institutionen för neurovetenskap4 aut |
710 | 2 | a Karolinska Institutetb Institutionen för neurovetenskap4 org |
773 | 0 | t Journal of Neuroscienced Karolinska Inst, Dept Neurosci, S-17177 Stockholm, Sweden. Karolinska Inst, Dept Cell & Mol Biol, Med Nobel Inst, S-17177 Stockholm, Sweden. Biomed Ctr, Dept Dev Neurosci, S-75123 Uppsala, Sweden. McGill Univ, Montreal Neurol Inst, Brain Tumor Res Ctr, Montreal, PQ H3A 2B4, Canada. : SOC NEUROSCIENCEg 18, s. 5714-q 18:15<5714-5722x 0270-6474x 1529-2401 |
773 | 0 | t J.Neurosci.d Karolinska Inst, Dept Neurosci, S-17177 Stockholm, Sweden. Karolinska Inst, Dept Cell & Mol Biol, Med Nobel Inst, S-17177 Stockholm, Sweden. Biomed Ctr, Dept Dev Neurosci, S-75123 Uppsala, Sweden. McGill Univ, Montreal Neurol Inst, Brain Tumor Res Ctr, Montreal, PQ H3A 2B4, Canada. : SOC NEUROSCIENCEg 18, s. 5714-q 18<5714- |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-168014 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1937761 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-56668 |
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