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The impact of regul...
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Kochovska, SlavicaUniversity of Wollongong
(författare)
The impact of regular, low-dose, sustained-release morphine for chronic breathlessness on caregiver burden : An exploratory analysis of the BEAMS trial
- Artikel/kapitelEngelska2024
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LIBRIS-ID:oai:lup.lub.lu.se:c0e751b3-a740-407d-8f03-49928fa9d5a5
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https://lup.lub.lu.se/record/c0e751b3-a740-407d-8f03-49928fa9d5a5URI
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https://doi.org/10.1177/02692163231211227DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
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Background: Chronic breathlessness adversely impacts people with chronic obstructive pulmonary disease and their caregivers (family and friends), who may, in turn, experience significant burden due to their caregiving role. Sustained-release morphine may reduce chronic breathlessness in some patients, which may have an impact on caregivers’ perceived burden. Aim: To explore the impact on caregiver burden of active treatment of people with chronic breathlessness (modified Medical Research Council (mMRC) ⩾ 3) and chronic obstructive pulmonary disease (COPD) with regular, low-dose, sustained-release morphine within a multi-site, double-blind, randomised, placebo-controlled trial. Design: Exploratory analysis of self-reported caregiver burden at baseline and end of week 3 in a randomised, double-blind, placebo-controlled study. Caregiver measures included: demographics and perceived burden (Zarit Burden Interview 12-item short-form questionnaire). Patient measures included: worst breathlessness and FitBitR-measures. Setting/participants: All consenting caregivers of trial patient participants in a multi-site study recruiting from palliative care and respiratory services. Results: Caregivers (n = 49; 59% women; median age 68 years [IQR 50–75]) reported median baseline caregiver burden 12 [IQR 5–17], with 53% reporting high burden (⩾13). Eighty-four percent of caregivers reported no change in burden. In people whose worst breathlessness improved, caregiver burden moved in the same direction, though the correlation was not significant (rs = 0.25, p = 0.17). Conversely, caregiver burden worsened as patients’ minutes lightly active increased, with the correlation being significant (rs = 0.56, p = 0.04). Conclusions: Caregivers reported high levels of caregiver burden, but patients’ response to treatment in terms of their symptom and function may influence change in caregiver burden over a three-week period.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Ferreira, DianaUniversity of Wollongong
(författare)
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Chang, SungwonUniversity of Technology Sydney
(författare)
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Luckett, TimUniversity of Technology Sydney
(författare)
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Roydhouse, JessicaMenzies Institute for Medical Research
(författare)
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Ekström, MagnusLund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Palliativt Utvecklingscentrum,Forskargrupper vid Lunds universitet,Andfåddhet och kronisk andningssvikt,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,The Institute for Palliative Care,Lund University Research Groups,Breathlessness and chronic respiratory failure(Swepub:lu)med-mue
(författare)
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Currow, David C.University of Wollongong
(författare)
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University of WollongongUniversity of Technology Sydney
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Palliative Medicine38:1, s. 156-1620269-2163
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