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Sökning: WFRF:(Saenger A. K.) > (2020-2023) > Antibody-mediated i...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005685naa a2200697 4500
001oai:gup.ub.gu.se/327276
003SwePub
008240528s2023 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-512523
024a https://gup.ub.gu.se/publication/3272762 URI
024a https://doi.org/10.1515/cclm-2023-00282 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5125232 URI
040 a (SwePub)gud (SwePub)uu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Hammarsten, Olau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin,Institute of Biomedicine,Univ Gothenburg, Dept Clin Chem & Transfus Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xhamol
2451 0a Antibody-mediated interferences affecting cardiac troponin assays: recommendations from the IFCC Committee on Clinical Applications of Cardiac Biomarkers
264 c 2023-03-24
264 1b Walter de Gruyter GmbH,c 2023
520 a The International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) provides educational documents to facilitate the interpretation and use of cardiac biomarkers in clinical laboratories and practice. Our aim is to improve the understanding of certain key analytical and clinical aspects of cardiac biomarkers and how these may interplay. Measurements of cardiac troponin (cTn) have a prominent place in the clinical work-up of patients with suspected acute coronary syndrome. It is therefore important that clinical laboratories know how to recognize and assess analytical issues. Two emerging analytical issues resulting in falsely high cTn concentrations, often several fold higher than the upper reference limit (URL), are antibody-mediated assay interference due to long-lived cTn-antibody complexes, called macrotroponin, and crosslinking antibodies that are frequently referred to as heterophilic antibodies. We provide an overview of antibody-mediated cTn assay interference and provide recommendations on how to confirm the interference and interpret the results.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng
653 a assay interference
653 a cardiac troponin
653 a heterophile antibodies
653 a immune
653 a complexes
653 a macrotroponin
653 a myocardial infarction
653 a macrotroponin
653 a admissions
653 a clearance
653 a serum
653 a Medical Laboratory Technology
653 a assay interference
700a Warner, J. V.u Univ Queensland, Fac Med, St Lucia, Australia.4 aut
700a Lam, L.u Auckland City Hosp, Chem Pathol, LabPlus, Auckland, New Zealand.;Middlemore Hosp Labs, Biochem, Auckland, New Zealand.,Univ Edinburgh, Univ Ctr Cardiovasc Sci, Usher Inst, BHF, Edinburgh, Scotland.4 aut
700a Kavsak, P.u McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada.4 aut
700a Lindahl, Bertil,d 1957-u Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)belin227
700a Aakre, K. M.u Haukeland Hosp, Dept Med Biochem & Pharmacol, Dept Heart Dis, Oslo, Norway.;Univ Bergen, Dept Clin Sci, Bergen, Norway.4 aut
700a Collinson, P.u St Georges Univ Hosp NHS Fdn Trust, Dept Clin Blood Sci & Cardiol, London, England.;St Georges Univ London, London, England.4 aut
700a Jaffe, A. S.u Mayo Clin, Dept Lab Med & Pathol & Cardiol, Rochester, MN USA.4 aut
700a Saenger, A. K.u Hennepin Healthcare, Dept Lab Med & Pathol, HCMC, Rochester, MN USA.;Univ Minnesota, Dept Lab Med & Pathol, Rochester, MN USA.4 aut
700a Body, R.u Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Emergency Dept, Manchester, England.;Univ Manchester, Div Cardiovasc Sci, Manchester, England.;Manchester Metropolitan Univ, Healthcare Sci Dept, Manchester, England.4 aut
700a Mills, N. L.4 aut
700a Omland, T.u Akershus Univ Hosp, Dept Cardiol, Akershus, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.4 aut
700a Ordonez-Llanos, J.u Hosp Santa Creu & Sant Pau, Serv Bioquim Clin, Madrid, Spain.;Fdn Biochem & Mol Pathol, Madrid, Spain.4 aut
700a Apple, F. S.u Hennepin Healthcare, Dept Lab Med & Pathol, HCMC, Rochester, MN USA.;Univ Minnesota, Dept Lab Med & Pathol, Rochester, MN USA.4 aut
710a Göteborgs universitetb Institutionen för biomedicin4 org
773t CLINICAL CHEMISTRY AND LABORATORY MEDICINEd : Walter de Gruyter GmbHg 61:8q 61:8x 1434-6621x 1437-4331
856u https://doi.org/10.1515/cclm-2023-0028y Fulltext
856u https://uu.diva-portal.org/smash/get/diva2:1800827/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://gup.ub.gu.se/publication/327276
8564 8u https://doi.org/10.1515/cclm-2023-0028
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-512523

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