Sökning: WFRF:(Saenger A. K.) > (2020-2023) > Antibody-mediated i...
Fältnamn | Indikatorer | Metadata |
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000 | 05685naa a2200697 4500 | |
001 | oai:gup.ub.gu.se/327276 | |
003 | SwePub | |
008 | 240528s2023 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-512523 | |
024 | 7 | a https://gup.ub.gu.se/publication/3272762 URI |
024 | 7 | a https://doi.org/10.1515/cclm-2023-00282 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5125232 URI |
040 | a (SwePub)gud (SwePub)uu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Hammarsten, Olau Gothenburg University,Göteborgs universitet,Institutionen för biomedicin,Institute of Biomedicine,Univ Gothenburg, Dept Clin Chem & Transfus Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xhamol |
245 | 1 0 | a Antibody-mediated interferences affecting cardiac troponin assays: recommendations from the IFCC Committee on Clinical Applications of Cardiac Biomarkers |
264 | c 2023-03-24 | |
264 | 1 | b Walter de Gruyter GmbH,c 2023 |
520 | a The International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) provides educational documents to facilitate the interpretation and use of cardiac biomarkers in clinical laboratories and practice. Our aim is to improve the understanding of certain key analytical and clinical aspects of cardiac biomarkers and how these may interplay. Measurements of cardiac troponin (cTn) have a prominent place in the clinical work-up of patients with suspected acute coronary syndrome. It is therefore important that clinical laboratories know how to recognize and assess analytical issues. Two emerging analytical issues resulting in falsely high cTn concentrations, often several fold higher than the upper reference limit (URL), are antibody-mediated assay interference due to long-lived cTn-antibody complexes, called macrotroponin, and crosslinking antibodies that are frequently referred to as heterophilic antibodies. We provide an overview of antibody-mediated cTn assay interference and provide recommendations on how to confirm the interference and interpret the results. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Biomedicinsk laboratorievetenskap/teknologi0 (SwePub)304022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Biomedical Laboratory Science/Technology0 (SwePub)304022 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Klinisk laboratoriemedicin0 (SwePub)302232 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Clinical Laboratory Medicine0 (SwePub)302232 hsv//eng |
653 | a assay interference | |
653 | a cardiac troponin | |
653 | a heterophile antibodies | |
653 | a immune | |
653 | a complexes | |
653 | a macrotroponin | |
653 | a myocardial infarction | |
653 | a macrotroponin | |
653 | a admissions | |
653 | a clearance | |
653 | a serum | |
653 | a Medical Laboratory Technology | |
653 | a assay interference | |
700 | 1 | a Warner, J. V.u Univ Queensland, Fac Med, St Lucia, Australia.4 aut |
700 | 1 | a Lam, L.u Auckland City Hosp, Chem Pathol, LabPlus, Auckland, New Zealand.;Middlemore Hosp Labs, Biochem, Auckland, New Zealand.,Univ Edinburgh, Univ Ctr Cardiovasc Sci, Usher Inst, BHF, Edinburgh, Scotland.4 aut |
700 | 1 | a Kavsak, P.u McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada.4 aut |
700 | 1 | a Lindahl, Bertil,d 1957-u Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)belin227 |
700 | 1 | a Aakre, K. M.u Haukeland Hosp, Dept Med Biochem & Pharmacol, Dept Heart Dis, Oslo, Norway.;Univ Bergen, Dept Clin Sci, Bergen, Norway.4 aut |
700 | 1 | a Collinson, P.u St Georges Univ Hosp NHS Fdn Trust, Dept Clin Blood Sci & Cardiol, London, England.;St Georges Univ London, London, England.4 aut |
700 | 1 | a Jaffe, A. S.u Mayo Clin, Dept Lab Med & Pathol & Cardiol, Rochester, MN USA.4 aut |
700 | 1 | a Saenger, A. K.u Hennepin Healthcare, Dept Lab Med & Pathol, HCMC, Rochester, MN USA.;Univ Minnesota, Dept Lab Med & Pathol, Rochester, MN USA.4 aut |
700 | 1 | a Body, R.u Manchester Univ NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Emergency Dept, Manchester, England.;Univ Manchester, Div Cardiovasc Sci, Manchester, England.;Manchester Metropolitan Univ, Healthcare Sci Dept, Manchester, England.4 aut |
700 | 1 | a Mills, N. L.4 aut |
700 | 1 | a Omland, T.u Akershus Univ Hosp, Dept Cardiol, Akershus, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.4 aut |
700 | 1 | a Ordonez-Llanos, J.u Hosp Santa Creu & Sant Pau, Serv Bioquim Clin, Madrid, Spain.;Fdn Biochem & Mol Pathol, Madrid, Spain.4 aut |
700 | 1 | a Apple, F. S.u Hennepin Healthcare, Dept Lab Med & Pathol, HCMC, Rochester, MN USA.;Univ Minnesota, Dept Lab Med & Pathol, Rochester, MN USA.4 aut |
710 | 2 | a Göteborgs universitetb Institutionen för biomedicin4 org |
773 | 0 | t CLINICAL CHEMISTRY AND LABORATORY MEDICINEd : Walter de Gruyter GmbHg 61:8q 61:8x 1434-6621x 1437-4331 |
856 | 4 | u https://doi.org/10.1515/cclm-2023-0028y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1800827/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 8 | u https://gup.ub.gu.se/publication/327276 |
856 | 4 8 | u https://doi.org/10.1515/cclm-2023-0028 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-512523 |
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