Search: WFRF:(Hamid N.) > (2015-2019) > Identification of r...
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000 | 27798naa a2203061 4500 | |
001 | oai:DiVA.org:uu-387924 | |
003 | SwePub | |
008 | 190627s2019 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3879242 URI |
024 | 7 | a https://doi.org/10.1038/s41591-019-0457-82 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Fresard, Laureu Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA4 aut |
245 | 1 0 | a Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts |
264 | c 2019-06-03 | |
264 | 1 | b NATURE PUBLISHING GROUP,c 2019 |
338 | a print2 rdacarrier | |
500 | a Group Authors: Undiagnosed Dis Network ; Care4Rare Canada Consortium | |
520 | a It is estimated that 350 million individuals worldwide suffer from rare diseases, which are predominantly caused by mutation in a single gene(1). The current molecular diagnostic rate is estimated at 50%, with whole-exome sequencing (WES) among the most successful approaches(2-5). For patients in whom WES is uninformative, RNA sequencing (RNA-seq) has shown diagnostic utility in specific tissues and diseases(6-8). This includes muscle biopsies from patients with undiagnosed rare muscle disorders(6,9), and cultured fibroblasts from patients with mitochondrial disorders(7). However, for many individuals, biopsies are not performed for clinical care, and tissues are difficult to access. We sought to assess the utility of RNA-seq from blood as a diagnostic tool for rare diseases of different pathophysiologies. We generated whole-blood RNA-seq from 94 individuals with undiagnosed rare diseases spanning 16 diverse disease categories. We developed a robust approach to compare data from these individuals with large sets of RNA-seq data for controls (n = 1,594 unrelated controls and n = 49 family members) and demonstrated the impacts of expression, splicing, gene and variant filtering strategies on disease gene identification. Across our cohort, we observed that RNA-seq yields a 7.5% diagnostic rate, and an additional 16.7% with improved candidate gene resolution. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
700 | 1 | a Smail, Craigu Stanford Univ, Biomed Informat Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Ferraro, Nicole M.u Stanford Univ, Biomed Informat Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Teran, Nicole A.u Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA4 aut |
700 | 1 | a Li, Xinu Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA4 aut |
700 | 1 | a Smith, Kevin S.u Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bonner, Devonu Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Kernohan, Kristin D.u Childrens Hosp Eastern Ontario, NSO, Ottawa, ON, Canada4 aut |
700 | 1 | a Marwaha, Shrutiu Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;Stanford Univ, Stanford Cardiovasc Inst, Sch Med, Stanford, CA 94305 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Zappala, Zacharyu Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA4 aut |
700 | 1 | a Balliu, Brunildau Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA4 aut |
700 | 1 | a Davis, Joe R.u Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA4 aut |
700 | 1 | a Liu, Boxiangu Stanford Univ, Sch Humanities & Sci, Dept Biol, Stanford, CA 94305 USA4 aut |
700 | 1 | a Prybol, Cameron J.u Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA4 aut |
700 | 1 | a Kohler, Jennefer N.u Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Zastrow, Diane B.u Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Reuter, Chloe M.u Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Fisk, Dianna G.u Stanford Univ, Sch Med, Stanford Med Clin Genom Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Grove, Megan E.u Stanford Univ, Sch Med, Stanford Med Clin Genom Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Davidson, Jean M.u Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Hartley, Tailau Univ Ottawa, Childrens Hosp Eastern Ontario, Res Inst, Ottawa, ON, Canada4 aut |
700 | 1 | a Joshi, Ruchiu Stanford Univ, Sch Med, Stanford Med Clin Genom Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Strober, Benjamin J.u Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD USA4 aut |
700 | 1 | a Utiramerur, Sowmithriu Stanford Univ, Sch Med, Stanford Med Clin Genom Program, Stanford, CA 94305 USA4 aut |
700 | 1 | a Lind, Larsu Uppsala universitet,Klinisk epidemiologi4 aut0 (Swepub:uu)larslind |
700 | 1 | a Ingelsson, Eriku Stanford Univ, Stanford Cardiovasc Inst, Sch Med, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Div Cardiovasc Med, Dept Med, Stanford, CA 94305 USA4 aut |
700 | 1 | a Battle, Alexisu Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD USA;Johns Hopkins Univ, Dept Comp Sci, Baltimore, MD 21218 USA4 aut |
700 | 1 | a Bejerano, Gillu Stanford Univ, Dept Comp Sci, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Dept Pediat, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Dept Dev Biol, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Dept Biomed Data Sci, Stanford, CA 94305 USA4 aut |
700 | 1 | a Bernstein, Jonathan A.u Stanford Univ, Sch Med, Dept Pediat, Stanford, CA 94305 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Ashley, Euan A.u Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA;Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;Stanford Univ, Sch Med, Div Cardiovasc Med, Dept Med, Stanford, CA 94305 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Boycott, Kym M.u Univ Ottawa, Childrens Hosp Eastern Ontario, Res Inst, Ottawa, ON, Canada4 aut |
700 | 1 | a Merker, Jason D.u Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Stanford Med Clin Genom Program, Stanford, CA 94305 USA;Univ N Carolina, Sch Med, Lineberger Comprehens Canc Ctr, Dept Pathol & Lab Med, Chapel Hill, NC 27515 USA;Univ N Carolina, Sch Med, Lineberger Comprehens Canc Ctr, Dept Genet, Chapel Hill, NC 27515 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Wheeler, Matthew T.u Stanford Univ, Stanford Ctr Undiagnosed Dis, Stanford, CA USA;Stanford Univ, Stanford Cardiovasc Inst, Sch Med, Stanford, CA 94305 USA;NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Montgomery, Stephen B.u Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA;Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA4 aut |
700 | 1 | a Adams, David R.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Aday, Aaronu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Alejandro, Mercedes E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Allard, Patricku NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Azamian, Mahshid S.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bacino, Carlos A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Baker, Evau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Balasubramanyam, Ashoku NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Barseghyan, Hayku NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Batzli, Gabriel F.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Beggs, Alan H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Behnam, Babaku NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bellen, Hugo J.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Berry, Gerard T.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bican, Annau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bick, David P.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Birch, Camille L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Boone, Braden E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Bostwick, Bret L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Briere, Lauren C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Brokamp, Ellyu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Brown, Donna M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Brush, Matthewu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Burke, Elizabeth A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Burrage, Lindsay C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Butte, Manish J.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Chen, Shanu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Clark, Gary D.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Coakley, Terra R.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Cogan, Joy D.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Colley, Heather A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Cooper, Cynthia M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Cope, Heidiu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Craigen, William J.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a D'Souza, Precillau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Davids, Mariskau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dayal, Jyoti G.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dell'Angelica, Esteban C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dhar, Shweta U.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dipple, Katrina M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Donnell-Fink, Laurel A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dorrani, Naghmehu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dorset, Daniel C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Douine, Emilie D.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Draper, David D.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Dries, Annika M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Duncan, Laurau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Eckstein, David J.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Emrick, Lisa T.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Eng, Christine M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Enns, Gregory M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Eskin, Asciau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Esteves, Ceciliau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Estwick, Tyrau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Fernandez, Lilianau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Ferreira, Carlosu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Fieg, Elizabeth L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Fisher, Paul G.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Fogel, Brent L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Friedman, Noah D.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Gahl, William A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Glanton, Emilyu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Godfrey, Rena A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Goldman, Alica M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Goldstein, David B.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Gould, Sarah E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Gourdine, Jean-Philippe F.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Groden, Catherine A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Gropman, Andrea L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Haendel, Melissau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Hamid, Rizwanu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Hanchard, Neil A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a High, Francesu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Holm, Ingrid A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Hom, Jasonu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Howerton, Ellen M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Huang, Yongu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Jamal, Farihau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Jiang, Yong-huiu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Johnston, Jean M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Jones, Angela L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Karaviti, Lefkotheau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Koeller, David M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Kohane, Isaac S.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Krasnewich, Donna M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Korrick, Susanu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Koziura, Maryu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Krier, Joel B.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Kyle, Jennifer E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lalani, Seema R.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lau, C. Christopheru NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lazar, Jozefu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a LeBlanc, Kimberlyu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lee, Brendan H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lee, Haneu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Levy, Shawn E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lewis, Richard A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Lincoln, Sharyn A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Loo, Sandra K.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Loscalzo, Josephu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Maas, Richard L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Macnamara, Ellen F.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a MacRae, Calum A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Maduro, Valerie V.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Majcherska, Marta M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Malicdan, May Christine V.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Mamounas, Laura A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Manolio, Teri A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Markello, Thomas C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Marom, Ronitu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Martin, G. Martinu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Martinez-Agosto, Julian A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a May, Thomasu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a McConkie-Rosell, Allynu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a McCormack, Colleen E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a McCray, Alexa T.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Metz, Thomas O.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Might, Matthewu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Moretti, Paolo M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Morimoto, Marieu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Mulvihill, John J.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Murdock, David R.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Murphy, Jennifer L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Muzny, Donna M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Nehrebecky, Michele E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Nelson, Stan F.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Newberry, J. Scottu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Newman, John H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Nicholas, Sarah K.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Novacic, Donnau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Orange, Jordan S.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Orengo, James P.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Pallais, J. Carlu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Palmer, Christina G. S.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Papp, Jeanette C.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Parker, Neil H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Pena, Loren D. M.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Phillips, John A., IIIu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Posey, Jennifer E.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Postlethwait, John H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Potocki, Lorraineu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Pusey, Barbara N.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Renteria, Geneceeu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Rives, Lynetteu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Robertson, Amy K.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Rodan, Lance H.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Rosenfeld, Jill A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Sampson, Jacinda B.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Samson, Susan L.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Schoch, Kellyu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Scott, Daryl A.u NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Shakachite, Lisau NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
700 | 1 | a Sharma, Prashantu NIH, Undiagnosed Dis Network, Bldg 10, Bethesda, MD 20892 USA4 aut |
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