Sökning: WFRF:(Ramesh B) > (2015-2019) > The Mycobacterium p...
Fältnamn | Indikatorer | Metadata |
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000 | 03603naa a2200433 4500 | |
001 | oai:DiVA.org:uu-298249 | |
003 | SwePub | |
008 | 160701s2016 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2982492 URI |
024 | 7 | a https://doi.org/10.1093/gbe/evw0492 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Das, Sarbashisu Uppsala universitet,Kemisk biologi4 aut0 (Swepub:uu)sarda235 |
245 | 1 0 | a The Mycobacterium phlei Genome :b Expectations and Surprises |
264 | c 2016-03-03 | |
264 | 1 | b Oxford University Press (OUP),c 2016 |
338 | a electronic2 rdacarrier | |
520 | a Mycobacterium phlei, a nontuberculosis mycobacterial species, was first described in 1898-1899. We present the complete genome sequence for the IV, phlei CCUG21000(T) type strain and the draft genomes for four additional strains. The genome size for all five is 5.3 Mb with 69.4% Guanine-Cytosine content. This is approximate to 0.35 Mbp smaller than the previously reported M. phlei RIVM draft genome. The size difference is attributed partly to large bacteriophage sequence fragments in the M. phlei RIVM genome. Comparative analysis revealed the following: 1) A CRISPR system similar to Type 1E (cas3) in M. phiei RIVM; 2) genes involved in polyamine metabolism and transport (potAD, potT) that are absent in other mycobacteria, and 3) strain specific variations in the number of sigma-factor genes. Moreover, M. phlei has as many as 82 mce (mammalian cell entry) homologs and many of the horizontally acquired genes in M. phlei are present in other environmental bacteria including mycobacteria that share similar habitat. Phylogenetic analysis based on 693 Mycobacterium core genes present in all complete mycobacterial genomes suggested that its closest neighbor is Mycobacterium smegmatis JS623 and Mycobacterium rhodesiae NBB3, while it is more distant to M. smegmatis mc2 155. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
653 | a Mycobacterium phlei genome sequence | |
653 | a mycobacterial growth | |
653 | a comparative genome analysis | |
653 | a mycobacterial phylogeny | |
700 | 1 | a Pettersson, B. M. Fredriku Uppsala universitet,Kemisk biologi4 aut0 (Swepub:uu)frpet227 |
700 | 1 | a Behra, Phani Rama Krishnau Uppsala universitet,Kemisk biologi4 aut0 (Swepub:uu)behph854 |
700 | 1 | a Ramesh, Malavikau Uppsala universitet,Kemisk biologi4 aut0 (Swepub:uu)malra274 |
700 | 1 | a Dasgupta, Santanuu Uppsala universitet,Mikrobiologi4 aut0 (Swepub:uu)sda03860 |
700 | 1 | a Bhattacharya, Aloku Jawaharlal Nehru Univ, Sch Computat & Integrat Sci, New Delhi 110067, India.;Jawaharlal Nehru Univ, Sch Life Sci, New Delhi 110067, India.4 aut |
700 | 1 | a Kirsebom, Leif A.u Uppsala universitet,Kemisk biologi4 aut0 (Swepub:uu)leifkirs |
710 | 2 | a Uppsala universitetb Kemisk biologi4 org |
773 | 0 | t Genome Biology and Evolutiond : Oxford University Press (OUP)g 8:4, s. 975-985q 8:4<975-985x 1759-6653 |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:945450/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://academic.oup.com/gbe/article-pdf/8/4/975/17476303/evw049.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-298249 |
856 | 4 8 | u https://doi.org/10.1093/gbe/evw049 |
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