WFRF:(Tretli S)
Sökning: WFRF:(Tretli S) > Metabolic syndrome ...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04402naa a2200649 4500 | |
| 001 | oai:DiVA.org:umu-42228 | |
| 003 | SwePub | |
| 008 | 110406s2011 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:0fc2029c-851c-4a3a-90fb-7f3e852ed4b0 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-422282 URI |
| 024 | 7 | a https://doi.org/10.1093/annonc/mdq5972 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/19856412 URI |
| 040 | a (SwePub)umud (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Nagel, G4 aut |
| 245 | 1 0 | a Metabolic syndrome and rare gynecological cancers in the Metabolic syndrome and Cancer project (Me-Can) |
| 264 | 1 | b Oxford Journals,c 2011 |
| 338 | a print2 rdacarrier | |
| 520 | a BACKGROUND: Risk factors for rare gynecological cancers are largely unknown. Initial research has indicated that the metabolic syndrome (MetS) or individual components could play a role. Materials and methods: The Metabolic syndrome and Cancer project cohort includes 288 834 women. During an average follow-up of 11 years, 82 vulvar, 26 vaginal and 43 other rare gynecological cancers were identified. Hazard ratios (HRs) were estimated fitting Cox proportional hazards regression models for tertiles and standardized z-scores [with a mean of 0 and a standard deviation (SD) of 1] of body mass index (BMI), blood pressure, glucose, cholesterol, triglycerides and MetS. Risk estimates were corrected for random error in the measurement of metabolic factors. RESULTS: The MetS was associated with increased risk of vulvar [HR 1.78, 95% confidence interval (CI) 1.30-2.41) and vaginal cancer (HR 1.87, 95% CI 1.07-3.25). Among separate MetS components, 1 SD increase in BMI was associated with overall risk (HR 1.43, 95% CI 1.23-1.66), vulvar (HR 1.36, 95% CI 1.11-1.69) and vaginal cancer (HR 1.79, 95% CI 1.30-2.46). Blood glucose and triglyceride concentrations were associated with increased risk of vulvar cancer (HR 1.98, 95% CI 1.10-3.58 and HR 2.09, 95% CI 1.39-3.15, respectively). CONCLUSION: The results from this first prospective study on rare gynecological cancers suggest that the MetS and its individual components may play a role in the development of these tumors. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 653 | a epidemiology | |
| 653 | a MetS | |
| 653 | a rare gynecological cancers | |
| 653 | a Oncology | |
| 653 | a Onkologi | |
| 653 | a onkologi | |
| 653 | a Oncology | |
| 653 | a epidemiology | |
| 653 | a MetS | |
| 653 | a rare gynecological cancers | |
| 700 | 1 | a Concin, H4 aut |
| 700 | 1 | a Bjørge, T4 aut |
| 700 | 1 | a Rapp, K4 aut |
| 700 | 1 | a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma |
| 700 | 1 | a Hallmans, Göranu Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001 |
| 700 | 1 | a Diem, G4 aut |
| 700 | 1 | a Häggström, Christelu Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)chlham02 |
| 700 | 1 | a Engeland, A4 aut |
| 700 | 1 | a Almquist, Martinu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-mal |
| 700 | 1 | a Jonsson, Håkanu Umeå universitet,Onkologi4 aut0 (Swepub:umu)hojo0001 |
| 700 | 1 | a Selmer, R4 aut |
| 700 | 1 | a Stocks, Tanjau Umeå University,Umeå universitet,Urologi och andrologi4 aut0 (Swepub:lu)med-tss |
| 700 | 1 | a Tretli, S4 aut |
| 700 | 1 | a Ulmer, H4 aut |
| 700 | 1 | a Stattin, Päru Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)past0003 |
| 700 | 1 | a Lukanova, A4 aut |
| 710 | 2 | a Kirurgib Forskargrupper vid Lunds universitet4 org |
| 773 | 0 | t Annals of Oncologyd : Oxford Journalsg 22:6, s. 1339-1345q 22:6<1339-1345x 0923-7534x 1569-8041 |
| 856 | 4 | u https://doi.org/10.1093/annonc/mdq597 |
| 856 | 4 | u http://dx.doi.org/10.1093/annonc/mdq597y FULLTEXT |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-42228 |
| 856 | 4 8 | u https://doi.org/10.1093/annonc/mdq597 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/1985641 |
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