WFRF:(Davi N.)
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Immunoglobulin sequence analysis and prognostication in CLL : guidelines from the ERIC review board for reliable interpretation of problematic cases
- Langerak, A. W. (author)
- Davi, F. (author)
- Ghia, P. (author)
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- Hadzidimitriou, A. (author)
- Potter, K. N. (author)
- Stamatopoulos, K. (author)
- Belessi, C. (author)
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- (creator_code:org_t)
- 2011-04-01
- 2011
- English.
- In: Leukemia. - : Springer Science and Business Media LLC. - 0887-6924 .- 1476-5551. ; 25:6, s. 979-984
- Journal article (peer-reviewed)
Abstract
Subject headings
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- prognostication in chronic lymphocytic leukemia (CLL) and the definition of standardized procedures has allowed reliable and reproducible results. Occasionally, a straightforward interpretation of the sequences is not possible because of the so-called 'problematic sequences' that do not fit the 'classic' interpretation and pose scientific questions at the cross-road between hematology and immunology. Thanks to a dedicated effort within the European Research Initiative on CLL (ERIC), we have now the possibility to present such cases, offer a scientific explanation and propose recommendations in terms of prognostication.
Keyword
- CLL
- immunoglobulin
- prognosis
- IGHV
- somatic mutation analysis
- MEDICINE
- MEDICIN
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- ref (subject category)
- art (subject category)
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- Langerak, A. W.
- Davi, F.
- Ghia, P.
- Hadzidimitriou, ...
- Murray, Fiona
- Potter, K. N.
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- Rosenquist, Rich ...
- Stamatopoulos, K ...
- Belessi, C.
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- Articles in the publication
- Leukemia
- By the university
- Uppsala University
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