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Life's Essential 8 is inversely associated with high-sensitivity C-reactive protein

Hebib, Lana (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
Herraiz-Adillo, Angel (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
Higueras-Fresnillo, Sara (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.;Univ Autonoma Madrid, Dept Phys Educ Sport & Human Motr, Madrid, Spain.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Department Physical Education, Sport and Human Motricity, Universidad Autónoma de Madrid, Madrid, Spain
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Berglind, Daniel (författare)
Karolinska Inst, Dept Global Publ Hlth, Stockholm, Sweden.;Ctr Epidemiol & Community Med, Stockholm, Region Stockhol, Sweden.,Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Centre for Epidemiology and Community Medicine, Region Stockholm, Stockholm, Sweden
Daka, Bledar (författare)
Univ Gothenburg, Inst Med, Sahlgrenska Acad, Sch Publ Hlth & Community Med, Gothenburg, Sweden.,School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Wennberg, Patrik, 1972- (författare)
Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
Hagström, Emil (författare)
Uppsala universitet,Kardiologi,Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
Lenander, Cecilia (författare)
Lund Univ, Ctr Primary Hlth Care Res, Dept Clin Sci Malmö, Lund, Sweden.,Department of Clinical Sciences in Malmö, Centre for Primary Health Care Research, Lund University, Lund, Sweden
Ahlqvist, Viktor H. (författare)
Aarhus Univ, Dept Biomed, Aarhus, Denmark.;Karolinska Inst, Inst Environm Med, Stockholm, Sweden.,Department of Biomedicine, Aarhus University, Aarhus, Denmark; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Ostgren, Carl Johan (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.;Linköping Univ, Ctr Med Image Sci & Visualizat CMIV, Linköping, Sweden.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Centre for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden
Radholm, Karin (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.;Univ New South Wales, George Inst Global Hlth, Sydney, Australia.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; The George Institute for Global Health, University of New South Wales, Sydney, Australia
Henriksson, Pontus (författare)
Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden.,Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden
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Linköping Univ, Dept Hlth Med & Caring Sci, Linköping, Sweden Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden (creator_code:org_t)
Springer Nature, 2024
2024
Engelska.
Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 14:1
Relaterad länk:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://umu.diva-por... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
https://urn.kb.se/re...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Life's Essential 8 (LE8) is a score that includes modifiable risk factors for cardiovascular disease. Four health behaviors (diet, physical activity, nicotine exposure and sleep health) and four health factors (non-HDL cholesterol, blood glucose, blood pressure and body mass index) are included. These modifiable risk factors promote inflammation, and inflammation is one of the biological mechanisms of cardiovascular disease development. Thus, we examined the relationship between cardiovascular health measured by LE8 and low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) in the cross-sectional population-based Swedish CArdioPulmonary bioImage Study (SCAPIS). The study consisted of 28,010 participants between 50 and 64 years (51.5% women, mean age 57.5 years). All individual LE8 components were assigned a score between 0 (unhealthy) and 100 (healthy) points, and a global score was calculated. The association between LE8 scores and high-risk hs-CRP (defined as > 3.0 mg/L) was analyzed using adjusted logistic regression with spline analyses. There was a strong, dose response and inverse association between LE8 scores and levels of hs-CRP. Thus, those with a low LE8 score (= 50.0 points) had 5.8 higher (95% confidence interval [CI] 5.2-6.4) odds ratio (OR) of having high hs-CRP as compared to those with a high LE8 score (= 80.0 points). In conclusion, our findings show strong inverse associations between LE8 scores and levels of hs-CRP.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Allmänmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- General Practice (hsv//eng)

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