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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005174naa a2200493 4500
001oai:DiVA.org:umu-36107
003SwePub
008100917s2010 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:2bb760be-abab-447c-8dd0-efcf43909a5a
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-361072 URI
0247 a https://doi.org/10.1158/1055-9965.EPI-10-02302 DOI
0247 a https://lup.lub.lu.se/record/16580322 URI
040 a (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Bjørge, Toneu Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway,Norwegian Institute of Public Health, Oslo/Bergen, Norway4 aut
2451 0a Metabolic syndrome and breast cancer in the me-can (metabolic syndrome and cancer) project.
264 1c 2010
338 a print2 rdacarrier
520 a BACKGROUND: Few studies have assessed the metabolic syndrome (MetS) as an entity in relation to breast cancer risk, and results have been inconsistent. We aimed to examine the association between MetS factors (individually and combined) and risk of breast cancer incidence and mortality. METHODS: Two hundred ninety thousand women from Austria, Norway, and Sweden were enrolled during 1974-2005, with measurements of height, weight, blood pressure, and levels of glucose, cholesterol, and triglycerides. Relative risks (RR) of breast cancer were estimated using Cox proportional hazards regression for each MetS factor in quintiles and for standardized levels (z-scores) and for a composite z-score for the MetS. RESULTS: There were 4,862 incident cases of breast cancer and 633 deaths from breast cancer identified. In women below age 50, there was a decreased risk of incident cancer for the MetS (per 1-unit increment of z-score; RR, 0.83; 95% confidence interval, 0.76-0.90) as well as for the individual factors (except for glucose). The lowest risks were seen among the heaviest women. In women above age 60, there was an increased risk of breast cancer mortality for the MetS (RR, 1.23; 95% confidence interval, 1.04-1.45) and for blood pressure and glucose. The strongest association with mortality was seen for increased glucose concentrations. CONCLUSIONS: The MetS was associated with a decreased risk of incident breast cancer in women below age 50 with high body mass index, and with an increased risk of breast cancer mortality in women above 60. IMPACT: Lifestyle interventions as recommended for cardiovascular disease prevention may be of value to prevent breast cancer mortality in postmenopausal women.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
7001 a Lukanova, Annekatrinu Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany4 aut
7001 a Jonsson, Håkanu Umeå universitet,Onkologi4 aut0 (Swepub:umu)hojo0001
7001 a Tretli, Steinaru Cancer Registry of Norway, Institute of Populationbased Cancer Research, Montebello, Oslo, Norway4 aut
7001 a Ulmer, Hannou Department of Medical Statistics, Informatics and Health Economics, Innsbruck Medical University, Innsbruck, Austria4 aut
7001 a Manjer, Jonasu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)smi-jma
7001 a Stocks, Tanjau Umeå University,Umeå universitet,Urologi och andrologi4 aut0 (Swepub:lu)med-tss
7001 a Selmer, Randiu Norwegian Institute of Public Health, Oslo/Bergen, Norway4 aut
7001 a Nagel, Gabrieleu Institute of Empidemiology, Ulm Univesity, Ulm, Germany4 aut
7001 a Almquist, Martinu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kir-mal
7001 a Concin, Hansu Agency for Preventive and Social Medicine, Bregenz, Austria4 aut
7001 a Hallmans, Göran,d 1947-u Umeå universitet,Näringsforskning4 aut0 (Swepub:umu)goha0001
7001 a Häggström, Christelu Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)chlham02
7001 a Stattin, Päru Umeå universitet,Urologi och andrologi4 aut0 (Swepub:umu)past0003
7001 a Engeland, Andersu Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway,Norwegian Institute of Public Health, Oslo/Bergen, Norway4 aut
7102 a Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norwayb Norwegian Institute of Public Health, Oslo/Bergen, Norway4 org
7730 t Cancer Epidemiology, Biomarkers and Preventiong 19:7, s. 1737-1745q 19:7<1737-1745x 1055-9965x 1538-7755
8564 u http://dx.doi.org/10.1158/1055-9965.EPI-10-0230y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36107
8564 8u https://doi.org/10.1158/1055-9965.EPI-10-0230
8564 8u https://lup.lub.lu.se/record/1658032

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