Interactions of Perfluorohexyloctane With Polyethylene and Polypropylene Pharmaceutical Packaging Materials.

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Kocherbitov Vitaly) > Interactions of Per...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		03855naa a2200457 4500
001		oai:DiVA.org:mau-17145
003		SwePub
008		200430s2020 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-171452 URI
024	7	a https://doi.org/10.1016/j.xphs.2020.03.0262 DOI
040		a (SwePub)mau
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Falk, Yana Znamenskayau Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:mau)HSYAZN
245	1 0	a Interactions of Perfluorohexyloctane With Polyethylene and Polypropylene Pharmaceutical Packaging Materials.
264	1	b Elsevier,c 2020
338		a electronic2 rdacarrier
520		a Semifluorinated alkanes (SFAs) are aprotic solvents, which may be used as drug solvents for topical ocular applications, for instance, in dry eye syndrome. Their physical properties suggest that they might be prone to interaction with plastic materials, such as, polyethylene (PE) and polypropylene (PP), which are commonly used as packaging materials for pharmaceutical products. In this study, we investigate interactions of PE and PP with a liquid SFA perfluorohexyloctane (PFHO) using differential scanning calorimetry (DSC), thermogravimetric analysis (TGA) and cross-polarized light microscopy. Binary phase diagrams of PFHO-PE and PFHO-PP systems demonstrating interactions of PFHO with the polymeric materials were constructed based on DSC data. According to this data, PFHO tends to lower the melting temperatures of PE and PP. The equilibrium values of solubilities of the polymers in PFHO and PFHO in the polymers were obtained by extrapolation of melting enthalpy data. Absorption of PFHO by PE and PP materials at ambient conditions after four weeks of equilibration was also studied by TGA. From the presented results, it may be concluded that thorough studies of interactions of PE or PP with SFAs are required when these materials are used as packaging components in SFA-based formulations.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Farmaceutiska vetenskaper0 (SwePub)301012 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Pharmaceutical Sciences0 (SwePub)301012 hsv//eng
653		a Extractables
653		a Leachables
653		a Phase diagram
653		a Polyethylene
653		a Polypropylene
653		a Semifluorinated alkanes
653		a Thermal analysis
700	1	a Runnsjö, Annau Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut
700	1	a Pettigrew, Anthonyu Anthony Pettigrew Associates Ltd, Liverpool, UK4 aut
700	1	a Scherer, Dieteru ApisPharma AG, CH-4242 Laufen, Switzerland4 aut
700	1	a Engblom, Johanu Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:mau)HSJOEN
700	1	a Kocherbitov, Vitalyu Malmö universitet,Institutionen för biomedicinsk vetenskap (BMV),Biofilms Research Center for Biointerfaces4 aut0 (Swepub:mau)HSVIKO
710	2	a Malmö universitetb Institutionen för biomedicinsk vetenskap (BMV)4 org
773	0	t Journal of Pharmaceutical Sciencesd : Elsevierg 109:7, s. 2180-2188q 109:7<2180-2188x 0022-3549x 1520-6017
856	4	u https://doi.org/10.1016/j.xphs.2020.03.026y Fulltext
856	4	u https://mau.diva-portal.org/smash/get/diva2:1427681/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4	u http://jpharmsci.org/article/S0022354920301854/pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-17145
856	4 8	u https://doi.org/10.1016/j.xphs.2020.03.026

Hitta via bibliotek

Journal of Pharmaceutical Sciences (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Falk, Yana Zname ...; Runnsjö, Anna; Pettigrew, Antho ...; Scherer, Dieter; Engblom, Johan; Kocherbitov, Vit ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinska och f ...; och Farmaceutiska ve ...

Artiklar i publikationen: Journal of Pharm ...

Av lärosätet: Malmö universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se