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Pressure distribution in mammography: compression of breasts with malignant tumor masses

Förnvik, Daniel (författare)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups
Dustler, Magnus (författare)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups
Andersson, Ingvar (författare)
Lund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Radiology Diagnostics, Malmö,Lund University Research Groups
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Brorson, Håkan (författare)
Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
Timberg, Pontus (författare)
Lund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Medicinsk strålningsfysik, Malmö,Radiology Diagnostics, Malmö,Lund University Research Groups,Medical Radiation Physics, Malmö
Zackrisson, Sophia (författare)
Lund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,Radiology Diagnostics, Malmö,Lund University Research Groups
Tingberg, Anders (författare)
Lund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups
visa färre...
 (creator_code:org_t)
SPIE, 2013
2013
Engelska.
Ingår i: Medical Imaging 2013: Physics of Medical Imaging. - : SPIE. - 1996-756X .- 0277-786X. ; 8668, s. 86684-86684
  • Konferensbidrag (refereegranskat)
Abstract Ämnesord
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  • The pressure distribution over a compressed breast is in general heterogeneous. In this study we investigated the pressure distribution over compressed breasts with tumor masses. Twenty-two women either recalled for work-up of findings suspicious for breast cancer in the screening program or with clinically suspected findings were included in the study. Twenty-one lesions turned out to be malignant and one benign. The distribution of compression pressure was measured using thin FSR (Force Sensing Resistor) pressure sensors attached to the compression plate. The pressure over the breast was ascertained by acquiring an x-ray image of the compressed breast with the pressure sensors present. The pressure data and the mammogram were used to create a composite image with pressure data displayed as a color overlay. The malignant tumor area generally matched an elevated pressure area and this pressure was generally higher than the pressure over surrounding parenchyma. In 11 out of 22 (50%) subjects the maximum pressure over the breast was located over the tumor. Only 4 out of 22 (18%) masses had a lower tumor mean pressure compared to the mean pressure over the breast (including one small < 10 mm tumor and one benign structure). The results suggest that tumors are stiffer, thus, absorbing more pressure compared to the surrounding parenchyma and that this property can be quantified. Refined pressure techniques could possibly be used to demonstrate the relative elasticity distribution in breast tissue, which might provide valuable differential diagnostic information.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Nyckelord

breast compression
mammography
pressure distribution
mechanical
imaging
elastic stiffness
stress/strain

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