Can probiotics modulate human disease by impacting intestinal barrier function?

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Fältnamn	Indikatorer	Metadata
000		04288naa a2200469 4500
001		oai:DiVA.org:oru-55041
003		SwePub
008		170310s2017 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-550412 URI
024	7	a https://doi.org/10.1017/S00071145160040372 DOI
040		a (SwePub)oru
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a for2 swepub-publicationtype
100	1	a Bron, Peter A.u NIZO Food Research, Ede, The Netherlands; BE-Basic Foundation, The Netherlands, Delft, The Netherlands4 aut
245	1 0	a Can probiotics modulate human disease by impacting intestinal barrier function?
264	1	a Cambridge, United Kingdom :b Cambridge University Press,c 2017
338		a print2 rdacarrier
500		a Funding Agencies:ILSI Europe Probiotic Task ForceFNRSFrench Cancer Research Association (ARC)Fonds de la Recherche Scientifique - FNRS WELBIO-CR-2012S-02RFunds InBev-Baillet LatourERC Starting GrantEuropean Research Council, Starting grant 336452-ENIGMO
520		a Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is balanced to maximise absorptive capacity, while maintaining efficient defensive reactions against chemical and microbial challenges. Evidence is mounting that disruption of epithelial barrier integrity is one of the major aetiological factors associated with several gastrointestinal diseases, including infection by pathogens, obesity and diabetes, necrotising enterocolitis, irritable bowel syndrome and inflammatory bowel disease. The notion that specific probiotic bacterial strains can affect barrier integrity fuelled research in which in vitro cell lines, animal models and clinical trials are used to assess whether probiotics can revert the diseased state back to homeostasis and health. This review catalogues and categorises the lines of evidence available in literature for the role of probiotics in epithelial integrity and, consequently, their beneficial effect for the reduction of gastrointestinal disease symptoms.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653		a Probiotics
653		a Gut microbiota
653		a Gut barrier
653		a Immunity
653		a Gastrointestinal disorders
700	1	a Kleerebezem, Michielu Host Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands4 aut
700	1	a Brummer, Robert-Jan,d 1957-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län4 aut0 (Swepub:oru)rnbr
700	1	a Cani, Patrice D.u Metabolism and Nutrition Research Group, WELBIO – Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium4 aut
700	1	a Mercenier, Annicku Nutrition and Health Research, Nestlé Research Center, Lausanne, Switzerland4 aut
700	1	a MacDonald, Thomas T.u Barts and The London school of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London, UK4 aut
700	1	a Garcia-Ródenas, Clara Lu Nutrition and Health Research, Nestlé Research Center, Lausanne, Switzerland4 aut
700	1	a Wells, Jerry M.u Host Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands4 aut
710	2	a NIZO Food Research, Ede, The Netherlands; BE-Basic Foundation, The Netherlands, Delft, The Netherlandsb Host Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands4 org
773	0	t British Journal of Nutritiond Cambridge, United Kingdom : Cambridge University Pressg 117:1, s. 93-107q 117:1<93-107x 0007-1145x 1475-2662
856	4	u https://doi.org/10.1017/S0007114516004037y Fulltext
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-55041
856	4 8	u https://doi.org/10.1017/S0007114516004037

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Av författaren/redakt...: Bron, Peter A.; Kleerebezem, Mic ...; Brummer, Robert- ...; Cani, Patrice D.; Mercenier, Annic ...; MacDonald, Thoma ...; visa fler...; Garcia-Ródenas, ...; Wells, Jerry M.; visa färre...

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