Lack of Prognostic Value of Type D Personality for Mortality in a Large Sample of Heart Failure Patients

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Lack of Prognostic Value of Type D Personality for Mortality in a Large Sample of Heart Failure Patients

Coyne, James C (författare): University of Groningen

Jaarsma, Tiny (författare): Linköpings universitet,Hälsa, Aktivitet, Vård (HAV),Hälsouniversitetet

Luttik, Marie-Louise (författare): University of Groningen

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van Sonderen, Eric (författare): University of Groningen

van Veldhuisen, Dirk J (författare): University of Groningen

Sanderman, Robbert (författare): University of Groningen

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Lippincott, Williams and Wilkins, 2011
2011
Engelska.
Ingår i: Psychosomatic Medicine. - : Lippincott, Williams and Wilkins. - 0033-3174 .- 1534-7796. ; 73:7, s. 557-562

Relaterad länk:: https://liu.diva-por... (primary) (Raw object); visa fler...; https://urn.kb.se/re...; https://doi.org/10.1...; visa färre...

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Background: Type D personality has been proposed as a prognostic indicator for mortality in cardiovascular disease. Most research examining this construct originates from one research group, and it is critical that the predictive value of Type D personality for adverse outcomes is independently cross-validated. This study examined its prognostic value in heart failure, relative to B-type natriuretic peptide (BNP) and depressive symptoms. Methods: We studied 706 patients with complete BNP, depressive symptom, and Type D personality and mortality data from 958 patients with heart failure enrolled after hospitalization for a multisite study of a disease management program. Multivariable models were adjusted for BNP and depression. Results: At 18 months, there were 192 deaths (27.2%). No evidence was found for a prognostic value of Type D personality in the unadjusted model (hazard ratio [HR] = 0.893, 95% confidence interval [CI] = 0.582-1.370). In contrast, BNP was significantly predictive of mortality (HR = 1.588, 95% CI = 1.391-1.812), whereas depression was not (HR = 1.011, 95% CI = 0.998-1.024). Type D was also not predictive in covariate-adjusted models (HR = 0.779, 95% CI = 0.489-1.242). Similar results were obtained when analyzing Type D as the interaction between continuous z scores of its two components, negative affectivity and social inhibition (p = .144). Conclusions: In the largest study to date, Type D does not predict mortality. Future research should construe Type D as the interaction of continuous negative affectivity and social inhibition z scores, rather than as a typology, and consider analyses replacing negative affectivity with depression.

Nyckelord

Type D personality
heart failure
survival
B-type natriuretic peptide
depression
MEDICINE
MEDICIN

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Av författaren/redakt...: Coyne, James C; Jaarsma, Tiny; Luttik, Marie-Lo ...; van Sonderen, Er ...; van Veldhuisen, ...; Sanderman, Robbe ...

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Av lärosätet: Linköpings universitet

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