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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004432naa a2200481 4500
001oai:lup.lub.lu.se:6ba43cef-325c-4e2c-b5ce-e2bc0e17d521
003SwePub
008160401s2011 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/23768582 URI
0247 a https://doi.org/10.1186/1749-8090-6-1632 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Offstad, Jon4 aut
2451 0a The Scandinavian multicenter hemodynamic evaluation of the SJM Regent aortic valve
264 c 2011-12-19
264 1b Springer Science and Business Media LLC,c 2011
338 a electronic2 rdacarrier
520 a Background: 112 patients who received small and medium sized St.Jude Regent heart valves (19-25 mm) at 7 Scandinavian centers were studied between January 2003 and February 2005 to obtain non-invasive data regarding the hemodynamic performance at rest and during Dobutamine stress echocardiography (DSE) testing one year after surgery. Material and methods: 46 woman and 66 men, aged 61.8 +/- 9.7 (18-75) years, were operated on for aortic regurgitation (17), stenosis (65), or mixed dysfunction (30). Valve sizes were 19 mm (6), 21 mm (33), 23 mm (41), 25 mm (30). Two patients receiving size 27 valves were excluded from the hemodynamic evaluation. Pledgets were used in 100 patients, everted mattress in 66 and simple interrupted sutures in 21. Valve orientation varied and was dependent on the surgeons' choice. 34 patients (30.4%) underwent concomitant coronary artery surgery. Results: There were two early deaths (1.8%) and three late deaths, one because of pancreatic cancer. Late events during follow-up were: non structural dysfunction (1), bleeding (2), thromboembolism (2). At one year follow up 93% of the patients were in NYHA classes 1-2 versus 47.8% preoperatively. Dobutamine stress echocardiography (DSE) was performed in a total of 66 and maximal peak stress was reached in 61 patients. During DSE testing, the following statistically significant changes took place: Heart rate increased by 73.0%, cardiac output by 85.5%, left ventriclular ejection fraction by 19.6%, and maximal mean prosthetic transvalvular gradient by 133.8%, whereas the effective orifice area index did not change. Left ventricular mass fell during one year from 215 +/- 63 to 197 +/- 62 g (p < 0.05). Conclusion: The Dobutamine test induces a substantial stress, well suitable for echocardiographic assessment of prosthesis valve function and can be performed in the majority of the patients. The changes in pressure gradients add to the hemodynamic characteristics of the various valve sizes. In our patients the St. Jude Regent valve performed satisfactory at rest and under pharmacological stress situation.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a Aortic valve replacement
653 a Mechanical heart valve
653 a Cardiac function
7001 a Andersen, Kai4 aut
7001 a Paulsson, Peru Lund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)thor-ppa
7001 a Andreasson, Jesper4 aut
7001 a Kjellman, Ulf4 aut
7001 a Lundblad, Oluf4 aut
7001 a Engstrom, Karl Gunnar4 aut
7001 a Haaverstad, Rune4 aut
7001 a Svennevig, Jan L.4 aut
7102 a Thoraxkirurgib Sektion II4 org
7730 t Journal of Cardiothoracic Surgeryd : Springer Science and Business Media LLCg 6:163q 6:163x 1749-8090
8564 u https://portal.research.lu.se/files/4032446/2861080.pdfx primaryx freey FULLTEXT
8564 u http://dx.doi.org/10.1186/1749-8090-6-163x freey FULLTEXT
8564 u https://cardiothoracicsurgery.biomedcentral.com/track/pdf/10.1186/1749-8090-6-163
8564 8u https://lup.lub.lu.se/record/2376858
8564 8u https://doi.org/10.1186/1749-8090-6-163

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