Spontaneous spinal cord infarctions: a systematic review and pooled analysis protocol

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El-Hajj, Victor GabrielKarolinska Univ Hosp, Dept Neurosurg, Stockholm, Sweden.;Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden. (författare)

Spontaneous spinal cord infarctions : a systematic review and pooled analysis protocol

Artikel/kapitelEngelska2023

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BMJ Publishing Group Ltd,2023
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LIBRIS-ID:oai:DiVA.org:uu-508974
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-508974URI
https://doi.org/10.1136/bmjopen-2022-071044DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:153323590URI

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Språk:engelska
Sammanfattning på:engelska

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IntroductionSpinal cord infarction (SCInf) is a rare ischaemic event that manifests with acute neurological deficits. It is typically classified as either spontaneous, defined as SCInf without any inciting event, or periprocedural, which typically occur in conjunction with vascular surgery with aortic manipulations. While periprocedural SCInf has recently been the subject of intensified research, especially focusing on the primary prevention of this complication, spontaneous SCInf remains less studied. Methods and analysisElectronic databases, including PubMed, Web of Science and Embase, will be searched using the keywords "spinal cord", "infarction", "ischemia" and "spontaneous". The search will be set to provide only English studies published from database inception. Editorials, letters and reviews will also be excluded. Reference lists of relevant records will also be searched. Identified studies will be screened for inclusion, by one reviewer in the first step and then three in the next step to decrease the risk of bias. The synthesis will address several topics of interest including epidemiology, presentation, diagnostics, treatment strategies, outcomes and predictors. The review aims to gather the body of evidence to summarise the current knowledge on SCInf. This will lead to a better understanding of the condition, its risk factors, diagnosis and management. Moreover, the review will also provide an understanding of the prognosis of patients with SCInf with respect to neurological function, quality of life and mortality. Finally, this overview of the literature will allow the identification of knowledge gaps to help guide future research efforts. Ethics and disseminationEthics approval was not required for our review as it is based on existing publications. The final manuscript will be submitted to a peer-reviewed journal.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
Stroke
Stroke medicine
Neurology

Biuppslag (personer, institutioner, konferenser, titlar ...)

Stenimahitis, VasiliosKarolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Neurol, Stockholm, Sweden. (författare)
Gharios, MariaKarolinska Inst, Dept Clin Neurosci, Stockholm, Sweden. (författare)
Mahdi, Omar AliKarolinska Inst, Dept Clin Neurosci, Stockholm, Sweden. (författare)
Elmi-Terander, AdrianKarolinska Institutet,Uppsala universitet,Institutionen för kirurgiska vetenskaper,Löwenströmska Hosp, Stockholm Spine Ctr, Upplands Väsby, Sweden.(Swepub:uu)adrel668 (författare)
Edström, ErikKarolinska Institutet (författare)
Karolinska Univ Hosp, Dept Neurosurg, Stockholm, Sweden.;Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Neurol, Stockholm, Sweden. (creator_code:org_t)

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Ingår i:BMJ Open: BMJ Publishing Group Ltd13:62044-6055

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Av författaren/redakt...: El-Hajj, Victor ...; Stenimahitis, Va ...; Gharios, Maria; Mahdi, Omar Ali; Elmi-Terander, A ...; Edström, Erik

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Neurologi

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

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Av lärosätet: Uppsala universitet; Karolinska Institutet

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