WFRF:(Stegmayr B)
Sökning: WFRF:(Stegmayr B) > Sex-specific time t...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04261naa a2200457 4500 | |
| 001 | oai:gup.ub.gu.se/330734 | |
| 003 | SwePub | |
| 008 | 240910s2023 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/3307342 URI |
| 024 | 7 | a https://doi.org/10.1080/0886022x.2023.22700782 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Nasic, Salmiru Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xnasal |
| 245 | 1 0 | a Sex-specific time trends of long-term graft survival after kidney transplantation - a registry-based study |
| 264 | 1 | c 2023 |
| 520 | a Background Sex-specific trends over time with respect to kidney graft survival have scarcely been described in earlier studies. The present study aimed to examine whether kidney graft survival differs between women and men over time.Methods This study was based on prospectively collected data extracted from a quality registry including all kidney transplant patients between January 1965 and September 2017 at the transplantation center of a university hospital in Sweden. The transplantation center serves a population of approximately 3.5 million inhabitants. Only the first graft for each patient was included in the study resulting in 4698 transplantations from unique patients (37% women, 63% men). Patients were followed-up until graft failure, death, or the end of the study. Death-censored graft survival analysis after kidney transplantation (KT) was performed using Kaplan-Meier analysis with log-rank test, and analysis adjusted for confounders was performed using multivariable Cox regression analysis.Results Median age at transplantation was 48 years (quartiles 36-57 years) and was similar for women and men. Graft survival was analyzed separately in four transplantation periods that represented various immunosuppressive regimes (1965-1985, 1986-1995, 1996-2005, and 2006-2017). Sex differences in graft survival varied over time (sex-by-period interaction, p = 0.026). During the three first periods, there were no significant sex differences in graft survival. However, during the last period, women had shorter graft survival (p = 0.022, hazard ratio (HR) 1.71, 95% confidence interval (CI) 1.1-2.7, adjusted for covariates). Biopsy-proven rejections were more common in women.Conclusions In this registry-based study, women had shorter graft survival than men during the last observation period (years 2006-2017). | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
| 653 | a Kidney graft survival | |
| 653 | a kidney transplants | |
| 653 | a sex-specific trends | |
| 653 | a disease | |
| 653 | a gender | |
| 653 | a impact | |
| 653 | a noncompliance | |
| 653 | a medication | |
| 653 | a patient | |
| 653 | a risk | |
| 653 | a Urology & Nephrology | |
| 700 | 1 | a Peters, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xpebjo |
| 700 | 1 | a Stegmayr, B.4 aut |
| 700 | 1 | a Kenne Sarenmalm, Elisabeth,d 1956u Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences4 aut0 (Swepub:gu)xkenel |
| 700 | 1 | a Afghahi, Henri,d 1966u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine4 aut0 (Swepub:gu)xafghe |
| 700 | 1 | a Eriksson, M.4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för medicin, avdelningen för molekylär och klinisk medicin4 org |
| 773 | 0 | t Renal Failureg 45:2q 45:2x 0886-022X |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/330734 |
| 856 | 4 8 | u https://doi.org/10.1080/0886022x.2023.2270078 |
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