Sökning: WFRF:(Ponten M) > The human secretome
Fältnamn | Indikatorer | Metadata |
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000 | 14562naa a2201249 4500 | |
001 | oai:gup.ub.gu.se/287931 | |
003 | SwePub | |
008 | 240528s2019 | |||||||||||000 ||eng| | |
009 | oai:research.chalmers.se:e67967c4-f946-4c7a-b135-72a8c66387bb | |
009 | oai:DiVA.org:kth-265462 | |
009 | oai:DiVA.org:uu-400051 | |
009 | oai:prod.swepub.kib.ki.se:142395621 | |
024 | 7 | a https://gup.ub.gu.se/publication/2879312 URI |
024 | 7 | a https://doi.org/10.1126/scisignal.aaz02742 DOI |
024 | 7 | a https://research.chalmers.se/publication/5144482 URI |
024 | 7 | a https://research.chalmers.se/publication/5142532 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2654622 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4000512 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1423956212 URI |
040 | a (SwePub)gud (SwePub)cthd (SwePub)kthd (SwePub)uud (SwePub)ki | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Uhlén, Mathiasu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden;Tech Univ Denmark, Ctr Biosustainabil, Lyngby, Denmark;Karolinska Inst, Dept Neurosci, Stockholm, Sweden4 aut0 (Swepub:kth)u1dulvmw |
245 | 1 0 | a The human secretome |
264 | 1 | b American Association for the Advancement of Science (AAAS),c 2019 |
500 | a QC 20191218 | |
520 | a The proteins secreted by human cells (collectively referred to as the secretome) are important not only for the basic understanding of human biology but also for the identification of potential targets for future diagnostics and therapies. Here, we present a comprehensive analysis of proteins predicted to be secreted in human cells, which provides information about their final localization in the human body, including the proteins actively secreted to peripheral blood. The analysis suggests that a large number of the proteins of the secretome are not secreted out of the cell, but instead are retained intracellularly, whereas another large group of proteins were identified that are predicted to be retained locally at the tissue of expression and not secreted into the blood. Proteins detected in the human blood by mass spectrometry-based proteomics and antibody-based immuno-assays are also presented with estimates of their concentrations in the blood. The results are presented in an updated version 19 of the Human Protein Atlas in which each gene encoding a secretome protein is annotated to provide an open-access knowledge resource of the human secretome, including body-wide expression data, spatial localization data down to the single-cell and subcellular levels, and data about the presence of proteins that are detectable in the blood. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Cell- och molekylärbiologi0 (SwePub)301082 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Cell and Molecular Biology0 (SwePub)301082 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Medicinsk bioteknologi0 (SwePub)304012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Medical Biotechnology0 (SwePub)304012 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Biokemi och molekylärbiologi0 (SwePub)106022 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Biochemistry and Molecular Biology0 (SwePub)106022 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Cellbiologi0 (SwePub)106042 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Cell Biology0 (SwePub)106042 hsv//eng |
653 | a protein import | |
653 | a Biochemistry & Molecular Biology | |
653 | a Cell Biology | |
700 | 1 | a Karlsson, Max J.u KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1hm1ssx |
700 | 1 | a Hober, Andreasu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u15bkxsl |
700 | 1 | a Svensson, Anne-Sophieu KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1t0mckt |
700 | 1 | a Scheffel, Juliau KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1y97f4h |
700 | 1 | a Kotol, Davidu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1yd1hdh |
700 | 1 | a Zhong, Wenu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1xwoji3 |
700 | 1 | a Tebani, Abdellahu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u17jnmwg |
700 | 1 | a Strandberg, Linneau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1jy95lk |
700 | 1 | a Edfors, Fredriku KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden;Stanford Univ, Dept Genet, Sch Med, Stanford, CA 94305 USA4 aut0 (Swepub:kth)u149ml0e |
700 | 1 | a Sjostedt, E.u Karolinska Institutet,Karolinska Inst, Dept Neurosci, Stockholm, Sweden.4 aut |
700 | 1 | a Schwenk, Jochen M.u Karolinska Institutet,KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1h7wtme |
700 | 1 | a Mardinoglu, Adilu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1t8kmr6 |
700 | 1 | a Berling, Annau KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u18q4b67 |
700 | 1 | a Ekblad, Siriu KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u13gulih |
700 | 1 | a Dannemeyer, Melanieu KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1u0d39z |
700 | 1 | a Kanje, Sara,d 1986-u KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1t204cn |
700 | 1 | a Rockberg, Johanu KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u130jo0a |
700 | 1 | a Lundqvist, Magnusu KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1hfekeg |
700 | 1 | a Malm, Magdalenau KTH,Proteinvetenskap4 aut0 (Swepub:kth)u1cmkpee |
700 | 1 | a Volk, Anna-Luisau KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1j049o2 |
700 | 1 | a Nilsson, Peteru KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1ws88sk |
700 | 1 | a Månberg, Anna,d 1985-u KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1g5roxd |
700 | 1 | a Dodig-Crnkovic, Teau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1wrth1x |
700 | 1 | a Pin, E.u KTH,Sci Life Lab, Dept Prot Sci, Stockholm, Sweden.,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut |
700 | 1 | a Zwahlen, M.u KTH,Sci Life Lab, Dept Prot Sci, Stockholm, Sweden.,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut |
700 | 1 | a Oksvold, P.u KTH,Sci Life Lab, Dept Prot Sci, Stockholm, Sweden.,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut |
700 | 1 | a von Feilitzen, Kalleu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1dbmi38 |
700 | 1 | a Häussler, Ragna S.u KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1izv3pd |
700 | 1 | a Hong, Mun-Gwanu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u19gmsru |
700 | 1 | a Lindskog, Ceciliau Uppsala universitet,Klinisk och experimentell patologi4 aut0 (Swepub:uu)cecli129 |
700 | 1 | a Pontén, Fredriku Uppsala universitet,Klinisk och experimentell patologi4 aut0 (Swepub:uu)fredpont |
700 | 1 | a Katona, Borbalau Uppsala universitet,Institutionen för immunologi, genetik och patologi4 aut0 (Swepub:uu)borka244 |
700 | 1 | a Vuu, Jimmyu Uppsala universitet,Klinisk och experimentell patologi4 aut0 (Swepub:uu)jimvu995 |
700 | 1 | a Lindström, Emilu Uppsala universitet,Institutionen för immunologi, genetik och patologi4 aut0 (Swepub:uu)emili335 |
700 | 1 | a Nielsen, Jens B,d 1962u Chalmers tekniska högskola,Chalmers University of Technology,Chalmers Univ Technol, Dept Chem & Biol Engn, Gothenburg, Sweden.4 aut0 (Swepub:cth)nielsenj |
700 | 1 | a Robinson, Jonathan,d 1986u Chalmers tekniska högskola,Chalmers University of Technology,Chalmers Univ Technol, Dept Chem & Biol Engn, Gothenburg, Sweden.4 aut0 (Swepub:cth)jonrob |
700 | 1 | a Ayoglu, Burcuu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1kfjubd |
700 | 1 | a Mahdessian, Dianau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1gwp2ka |
700 | 1 | a Sullivan, Devinu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u17a9k6f |
700 | 1 | a Thul, Peteru KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1j34ncc |
700 | 1 | a Danielsson, Fridau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1cx4q8o |
700 | 1 | a Stadler, Charlotteu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1r100ik |
700 | 1 | a Lundberg, Emmau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u12bylj1 |
700 | 1 | a Bergström, Göran,d 1964u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,University of Gothenburg,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Mol & Clin Med, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Clin Physiol, Gothenburg, Region Vastra G, Sweden.4 aut0 (Swepub:gu)xbgort |
700 | 1 | a Gummesson, Anders,d 1973u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,University of Gothenburg,Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Mol & Clin Med, Gothenburg, Sweden.4 aut0 (Swepub:gu)xguman |
700 | 1 | a Voldborg, B. G.u Danmarks Tekniske Universitet,Technical University of Denmark,Tech Univ Denmark, Ctr Biosustainabil, Lyngby, Denmark.4 aut |
700 | 1 | a Tegel, Hannau KTH,Proteinvetenskap,Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden.,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1nou8yx |
700 | 1 | a Hober, Sophiau KTH,Proteinvetenskap,KTH Royal Inst Technol, Albanova Univ Ctr, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u11qqzc1 |
700 | 1 | a Forsström, Björnu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u11i5nju |
700 | 1 | a Schwenk, J. M.u Karolinska Inst, Dept Neurosci, Stockholm, Sweden4 aut |
700 | 1 | a Fagerberg, Linnu KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u1dglfid |
700 | 1 | a Sivertsson, Åsau KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Dept Prot Sci, Stockholm, Sweden4 aut0 (Swepub:kth)u195d5b0 |
710 | 2 | a KTHb Proteinvetenskap4 org |
773 | 0 | t Science Signalingd : American Association for the Advancement of Science (AAAS)g 12:609q 12:609x 1945-0877x 1937-9145 |
856 | 4 | u https://research.chalmers.se/publication/514448/file/514448_Fulltext.pdf |
856 | 4 | u https://research.chalmers.se/publication/514448/file/514448_Fulltext.pdfx primaryx freey FULLTEXT |
856 | 4 8 | u https://gup.ub.gu.se/publication/287931 |
856 | 4 8 | u https://doi.org/10.1126/scisignal.aaz0274 |
856 | 4 8 | u https://research.chalmers.se/publication/514448 |
856 | 4 8 | u https://research.chalmers.se/publication/514253 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-265462 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-400051 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:142395621 |
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