Sökning: WFRF:(Rydberg Lennart 1944) > Characterisation of...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04857naa a2200625 4500 | |
001 | oai:gup.ub.gu.se/111146 | |
003 | SwePub | |
008 | 240528s1992 | |||||||||||000 ||eng| | |
024 | 7 | a https://gup.ub.gu.se/publication/1111462 URI |
040 | a (SwePub)gu | |
041 | a eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Rydberg, Lennart,d 1944u Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine4 aut0 (Swepub:gu)xrydle |
245 | 1 0 | a Characterisation of the anti-A antibody response following an ABO incompatible (A2 to O) kidney transplantation. |
264 | 1 | c 1992 |
520 | a Anti-A,B antibodies produced in a blood group OLe(a-b-) recipient receiving a kidney graft from a blood group A2Le(a-b+) donor have been analysed for their ability to bind to different glycosphingolipid antigens. Solid-phase RIA using pure glycosphingolipid antigens and a chromatogram binding assay using total nonacid glycosphingolipid fractions from erythrocytes of different human blood group phenotypes together with pure glycolipid antigens were used as assay systems. Serum antibodies were shown to bind equally well to A (types 1, 2, 3 and 4) and B (types 1 and 2) antigenic structures but no binding to H antigens (types 1, 2 and 4) was detected. After adsorption of serum antibodies on A1 Le(a-b+) erythrocytes there was a residual anti-A antibody activity which could not be adsorbed by synthetic A-trisaccharides coupled to crystalline silica (Synsorb-A). These residual antibodies, which are not present in a pretransplant serum sample, had a specificity for the A antigen with type 1 core saccharide chain and the binding epitope obviously included both the N-acetylgalactosamine and the N-acetylglucosamine. The fucose residue was apparently not obligate for binding. The conformation of the sugar units involved in the binding epitope was determined. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Annan klinisk medicin0 (SwePub)302992 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Other Clinical Medicine0 (SwePub)302992 hsv//eng |
653 | a ABO Blood-Group System | |
653 | a Adult | |
653 | a Antibody Formation | |
653 | a Antibody Specificity | |
653 | a Blood Group Incompatibility | |
653 | a immunology | |
653 | a Carbohydrate Sequence | |
653 | a Epitopes | |
653 | a chemistry | |
653 | a Humans | |
653 | a Immunoglobulin A | |
653 | a analysis | |
653 | a Immunoglobulin G | |
653 | a analysis | |
653 | a Immunoglobulin M | |
653 | a analysis | |
653 | a Kidney Transplantation | |
653 | a immunology | |
653 | a Male | |
653 | a Models | |
653 | a Molecular | |
653 | a Molecular Conformation | |
653 | a Molecular Sequence Data | |
653 | a Radioimmunoassay | |
653 | a Time Factors | |
700 | 1 | a Breimer, Michael,d 1951u Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för kirurgi,Institute of Surgical Sciences, Department of Surgery4 aut0 (Swepub:gu)xbremi |
700 | 1 | a Holgersson, Janu Gothenburg University,Göteborgs universitet,Institutionen för medicinsk och fysiologisk kemi,Institute of Medical Biochemistry4 aut0 (Swepub:gu)xholgj |
700 | 1 | a Karlsson, Karl-Anders,d 1935u Gothenburg University,Göteborgs universitet,Institutionen för medicinsk och fysiologisk kemi,Institute of Medical Biochemistry4 aut0 (Swepub:gu)xkarlk |
700 | 1 | a Nyholm, Per-Georg,d 1958u Gothenburg University,Göteborgs universitet,Institutionen för medicinsk och fysiologisk kemi,Institute of Medical Biochemistry4 aut0 (Swepub:gu)xnyhpe |
700 | 1 | a Pascher, Iu Gothenburg University,Göteborgs universitet,Institutionen för medicinsk och fysiologisk kemi,Institute of Medical Biochemistry4 aut |
700 | 1 | a Svensson, Lola,d 1948u Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine4 aut0 (Swepub:gu)xsvelo |
700 | 1 | a Samuelsson, Bo,d 1942u Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin,Institute of Laboratory Medicine, Dept of Clinical Chemistry/Transfusion Medicine4 aut0 (Swepub:gu)xsamub |
710 | 2 | a Göteborgs universitetb Institutionen för laboratoriemedicin, Avdelningen för klinisk kemi/transfusionsmedicin4 org |
773 | 0 | t Molecular immunologyg 29:4, s. 547-60q 29:4<547-60x 0161-5890 |
856 | 4 8 | u https://gup.ub.gu.se/publication/111146 |
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