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Carbamate pesticide...
Carbamate pesticides exposure and delayed physical development at the age of seven : Evidence from the SMBCS study
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- Zhang, Jiming (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Guo, Jianqiu (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Wu, Chunhua (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Qi, Xiaojuan (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology, Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China; Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China
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- Jiang, Shuai (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Lv, Shenliang (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Lu, Dasheng (författare)
- Shanghai Center for Disease Control and Prevention, Shanghai, China
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- Liang, Weijiu (författare)
- Changning Center for Disease Control and Prevention, Shanghai, China
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- Chang, Xiuli (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Zhang, Yubin (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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- Cao, Yang, Associate Professor, 1972- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics
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- Zhou, Zhijun (författare)
- School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China
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(creator_code:org_t)
- Elsevier, 2022
- 2022
- Engelska.
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Ingår i: Environment International. - : Elsevier. - 0160-4120 .- 1873-6750. ; 160
- Relaterad länk:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Carbamate pesticides are widely used in agriculture and cause widespread human exposure. The health effect of carbamates on physical development remains unclear. The current study aimed to explore the carbamate's health effect on physical development.METHODS: Prenatal, 3-year-old, 7-year-old urinary carbofuranphenol concentration was measured by gas chromatography tandem mass spectrometry and adjusted by creatinine. Anthropometric indices were measured by standard method and z-score standardized. Generalized linear models (GLM) were using to assess associations between exposure measurements and anthropometric indices. The generalized estimate equation (GEE) was applied to analyze the association between multiperiod exposure and anthropometric indices, and time-interaction terms were used to exam health effect consistency of exposure in each period. Gender-stratified analysis were conducted according to results of gender-interaction terms to identify gender-specific effects.RESULTS: The gender-interaction term of prenatal exposure with height z-score was significant (β = -0.057; 95% CI: -0.113, -0.001; p = 0.045). The 3-year-old carbofuranphenol level showed negative associations with weight z-score (β = -0.019; 95% CI: -0.038, -0.000; p = 0.040), height z-score (β = -0.015; 95% CI: -0.028, -0.001; p = 0.026), chest circumference (β = -0.086; 95% CI: -0.171, -0.001; p = 0.046), and waist circumference (β = -0.128; 95% CI: -0.230, -0.026; p = 0.014). No statistically significant trend was found for prenatal and 7-year-old carbofuranphenol levels. In GEEs, carbofuranphenol level was negatively associated with weight z-score (β = -0.103; 95% CI: -0.195, -0.011; p = 0.027), height z-score (β = -0.087; 95% CI: -0.152, -0.022; p = 0.008), and chest circumference (β = -0.472; 95% CI: -0.918, -0.026; p = 0.037). Boy's height z-score was inversely associated with carbamate exposure (β = -0.140; 95% CI: -0.227, -0.053; p = 0.001).CONCLUSIONS: Prenatal and postnatal carbamate exposure may affect physical developmental process.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- Birth cohort
- Carbamate pesticides
- Carbofuranphenol
- Physical development
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Zhang, Jiming
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Guo, Jianqiu
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Wu, Chunhua
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Qi, Xiaojuan
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Jiang, Shuai
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Lv, Shenliang
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Lu, Dasheng
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Liang, Weijiu
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Chang, Xiuli
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Zhang, Yubin
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Cao, Yang, Assoc ...
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Zhou, Zhijun
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Arbetsmedicin oc ...
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Environment Inte ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet