SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Buchbinder D)
 

Sökning: WFRF:(Buchbinder D) > Characteristics of ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005926naa a2201021 4500
001oai:DiVA.org:uu-374020
003SwePub
008190117s2019 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:140223142
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3740202 URI
024a https://doi.org/10.1016/j.bbmt.2018.09.0312 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1402231422 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Norkin, Maxim4 aut
2451 0a Characteristics of Late Fatal Infections after Allogeneic Hematopoietic Cell Transplantation
264 1b Elsevier BV,c 2019
338 a print2 rdacarrier
520 a We analyzed late fatal infections (LFIs) in allogeneic stem cell transplantation (HCT) recipients reported to the Center for International Blood and Marrow Transplant Research. We analyzed the incidence, infection types, and risk factors contributing to LFI in 10,336 adult and 5088 pediatric subjects surviving for ≥2 years after first HCT without relapse. Among 2245 adult and 377 pediatric patients who died, infections were a primary or contributory cause of death in 687 (31%) and 110 (29%), respectively. At 12 years post-HCT, the cumulative incidence of LFIs was 6.4% (95% confidence interval [CI], 5.8% to 7.0%) in adults, compared with 1.8% (95% CI, 1.4% to 2.3%) in pediatric subjects; P < .001). In adults, the 2 most significant risks for developing LFI were increasing age (20 to 39, 40 to 54, and ≥55 years versus 18 to 19 years) with hazard ratios (HRs) of 3.12 (95% CI, 1.33 to 7.32), 3.86 (95% CI, 1.66 to 8.95), and 5.49 (95% CI, 2.32 to 12.99) and a history of chronic graft-versus-host disease GVHD (cGVHD) with ongoing immunosuppression at 2 years post-HCT compared with no history of GVHD with (HR, 3.87; 95% CI, 2.59 to 5.78). In pediatric subjects, the 3 most significant risks for developing LFI were a history of cGVHD with ongoing immunosuppression (HR, 9.49; 95% CI, 4.39 to 20.51) or without ongoing immunosuppression (HR, 2.7; 95% CI, 1.05 to 7.43) at 2 years post-HCT compared with no history of GVHD, diagnosis of inherited abnormalities of erythrocyte function compared with diagnosis of acute myelogenous leukemia (HR, 2.30; 95% CI, 1.19 to 4.42), and age >10 years (HR, 1.92; 95% CI, 1.15 to 3.2). This study emphasizes the importance of continued vigilance for late infections after HCT and institution of support strategies aimed at decreasing the risk of cGVHD.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653 a Adults
653 a Hematopoietic cell transplantation
653 a Infection
653 a Late fatal infection
653 a Pediatrics
700a Shaw, Bronwen E4 aut
700a Brazauskas, Ruta4 aut
700a Tecca, Heather R4 aut
700a Leather, Helen L4 aut
700a Gea-Banacloche, Juan4 aut
700a T Kamble, Rammurti4 aut
700a DeFilipp, Zachariah4 aut
700a Jacobsohn, David A4 aut
700a Ringden, Olleu Karolinska Institutet4 aut
700a Inamoto, Yoshihiro4 aut
700a A Kasow, Kimberly4 aut
700a Buchbinder, David4 aut
700a Shaw, Peter4 aut
700a Hematti, Peiman4 aut
700a Schears, Raquel4 aut
700a Badawy, Sherif M4 aut
700a Lazarus, Hillard M4 aut
700a Bhatt, Neel4 aut
700a Horn, Biljana4 aut
700a Chhabra, Saurabh4 aut
700a M Page, Kristin4 aut
700a Hamilton, Betty4 aut
700a Hildebrandt, Gerhard C4 aut
700a Yared, Jean A4 aut
700a Agrawal, Vaibhav4 aut
700a M Beitinjaneh, Amer4 aut
700a Majhail, Navneet4 aut
700a Kindwall-Keller, Tamila4 aut
700a Olsson, Richard F.u Karolinska Institutet,Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Division of Therapeutic Immunology, Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden4 aut0 (Swepub:uu)riols677
700a Schoemans, Helene4 aut
700a Gale, Robert Peter4 aut
700a Ganguly, Siddhartha4 aut
700a A Ahmed, Ibrahim4 aut
700a Schouten, Harry C4 aut
700a L Liesveld, Jane4 aut
700a Khera, Nandita4 aut
700a Steinberg, Amir4 aut
700a Shah, Ami J4 aut
700a Solh, Melhem4 aut
700a Marks, David I4 aut
700a Rybka, Witold4 aut
700a Aljurf, Mahmoud4 aut
700a Dietz, Andrew C4 aut
700a Gergis, Usama4 aut
700a George, Biju4 aut
700a Seo, Sachiko4 aut
700a Flowers, Mary E D4 aut
700a Battiwalla, Minoo4 aut
700a Savani, Bipin N4 aut
700a Riches, Marcie L4 aut
700a Wingard, John R4 aut
710a Karolinska Institutetb Centrum för klinisk forskning i Sörmland (CKFD)4 org
773t Biology of blood and marrow transplantationd : Elsevier BVg 25:2, s. 362-368q 25:2<362-368x 1083-8791x 1523-6536
856u http://www.bbmt.org/article/S1083879118305986/pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-374020
8564 8u https://doi.org/10.1016/j.bbmt.2018.09.031
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:140223142

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy