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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004017naa a2200529 4500
001oai:gup.ub.gu.se/205366
003SwePub
008240528s2014 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/2053662 URI
024a https://doi.org/10.1002/etc.26802 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Brown, Jeffrey Nu Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology4 aut0 (Swepub:gu)xbroje
2451 0a AQUEOUSANDLIPID NUCLEAR MAGNETIC RESONANCE METABOLOMIC PROFILES OF THE EARTHWORM APORRECTODEA CALIGINOSA SHOW POTENTIAL AS AN INDICATOR SPECIES FOR ENVIRONMENTAL METABOLOMICS
264 c 2014-08-22
264 1b Wiley,c 2014
520 a The common pasture earthworm Aporrectodea caliginosa has often been neglected in environmental metabolomics in favor of species easily bred in the laboratory. The present study assigns aqueous metabolites in A. caliginosa using high-resolution 1- and 2-dimensional nuclear magnetic resonance (NMR) spectroscopy. In total, 51 aqueous metabolites were identified, including typical amino acids (alanine, leucine, asparagine, phenylalanine), sugars (maltose, glucose), the dominant earthworm-specific 2-hexyl-5-ethyl-furansulfonate, and several previously unreported metabolites (oxoglutarate, putrescine). Examining the lesser-known earthworm lipid metabolome showed various lipid fatty acyl chains, cholesterol, and phosphatidylcholine. To briefly test if the NMR metabolomic techniques could differentiate A. caliginosa from different sites, earthworms were collected from 2 adjacent farms. Orthogonal partial least squares discriminant analysis detected metabolomic differences, suggesting the worms from the 2 sites differed in their energy metabolism, as indicated by altered levels of alanine, glutamine, glutamate, malate, fumarate, and lipids. Evidence of greater utilization of lipid energy reserves and onset of protein catabolism was also present. While the precise cause of the metabolomic differences could not be determined, the results show the potential of this species for further environmental metabolomic studies. Environ Toxicol Chem 2014;33:2313-2322. (c) 2014 SETAC
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaper0 (SwePub)3012 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicine0 (SwePub)3012 hsv//eng
653 a Nuclear magnetic resonance metabolomics
653 a Earthworm
653 a Lipid
653 a Amino acid
653 a Aporrectodea caliginosa
653 a HIGH-FIELD H-1-NMR
653 a EISENIA-VENETA
653 a LUMBRICUS-TERRESTRIS
653 a NMR
653 a EXPOSURE
653 a SOIL
653 a SPECTROSCOPY
653 a RESPONSES
653 a IDENTIFICATION
653 a PHENANTHRENE
653 a Environmental Sciences
653 a Toxicology
700a Samuelsson, Linda,d 1973u Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology4 aut0 (Swepub:gu)xsamli
700a Bernardi, G.4 aut
700a Gooneratne, R.4 aut
700a Larsson, D. G. Joakim,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xlarjo
710a Göteborgs universitetb Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi4 org
773t Environmental Toxicology and Chemistryd : Wileyg 33:10, s. 2313-2322q 33:10<2313-2322x 0730-7268
8564 8u https://gup.ub.gu.se/publication/205366
8564 8u https://doi.org/10.1002/etc.2680

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