Effect of Excess Body Weight on the Genetic Susceptibility to Cancer

• Excess body weight and genetics play important roles in cancer susceptibility. Although several studies have reported on obesity and genetic variants as separate risk factors for cancer, very few studies have investigated the interaction between excess body weight and genetic variants in cancer susceptibility. In this review, we focus on the interplay between these 2 risk factors, which are a major determinant of the individual risk of cancer onset.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

obesity

genetic susceptibility

insulin resistance

cancer

IRS1

OBESE INDIVIDUALS

LIVER-DISEASE

MASS INDEX

US ADULTS

RISK

POLYMORPHISM

VARIANT

METAANALYSIS

CARCINOMA

IRS1

Gastroenterology & Hepatology

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)