L773:1355 6177 OR L773:1469 7661
Sökning: L773:1355 6177 OR L773:1469 7661 > Preclinical Cogniti...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03490naa a2200421 4500 | |
| 001 | oai:DiVA.org:su-74155 | |
| 003 | SwePub | |
| 008 | 120301s2012 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:124167893 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-741552 URI |
| 024 | 7 | a https://doi.org/10.1017/S13556177110017182 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1241678932 URI |
| 040 | a (SwePub)sud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Laukka, Erika J.u Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 aut |
| 245 | 1 0 | a Preclinical Cognitive Trajectories Differ for Alzheimer's Disease and Vascular Dementia |
| 264 | 1 | c 2012 |
| 338 | a print2 rdacarrier | |
| 500 | a 4 | |
| 520 | a We investigated differences between Alzheimer's disease (AD) and vascular dementia (VaD) from the appearance of the first cognitive symptoms, focusing on both time of onset and rate of accelerated decline for different cognitive functions before dementia diagnosis. Data from a longitudinal population-based study were used, including 914 participants (mean age = 82.0 years, SD = 5.0) tested with a cognitive battery (word recall and recognition, Block Design, category fluency, clock reading) on up to four occasions spanning 10 years. We fit a series of linear mixed effects models with a change point to the cognitive data, contrasting each dementia group to a control group. Significant age-related decline was observed for all five cognitive tasks. Relative to time of diagnosis, the preclinical AD persons deviated from the normal aging curve earlier (up to 9 years) compared to the preclinical VaD persons (up to 6 years). However, once the preclinical VaD persons started to decline, they deteriorated at a faster rate than the preclinical AD persons. The results have important implications for identifying the two dementia disorders at an early stage and for selecting cognitive tasks to evaluate treatment effects for persons at risk of developing AD and VaD. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
| 653 | a Neuropsychology | |
| 653 | a Memory | |
| 653 | a Cognitive decline | |
| 653 | a Change point | |
| 653 | a Longitudinal studies | |
| 700 | 1 | a MacDonald, Stuart W.S.u Univ Victoria, Dept Psychol, Victoria, BC, Canada4 aut |
| 700 | 1 | a Fratiglioni, Laurau Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 aut |
| 700 | 1 | a Bäckman, Larsu Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 aut |
| 710 | 2 | a Stockholms universitetb Centrum för forskning om äldre och åldrande (ARC), (tills m KI)4 org |
| 773 | 0 | t Journal of the International Neuropsychological Societyg 18:2, s. 1-9q 18:2<1-9x 1355-6177x 1469-7661 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-74155 |
| 856 | 4 8 | u https://doi.org/10.1017/S1355617711001718 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:124167893 |
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