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Sökning: L773:1745 6673 > (2020-2022) > The value of fracti...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004624naa a2200613 4500
001oai:gup.ub.gu.se/317657
003SwePub
008240910s2022 | |||||||||||000 ||eng|
024a https://gup.ub.gu.se/publication/3176572 URI
024a https://doi.org/10.1186/s12995-022-00355-12 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Otelea, M. R.4 aut
2451 0a The value of fractional exhaled nitric oxide in occupational diseases - a systematic review
264 c 2022-07-25
264 1b Springer Science and Business Media LLC,c 2022
520 a Fractional exhaled nitric oxide (FeNO) is a non-invasive biomarker of respiratory tract inflammation, originally designated to identify eosinophilic airway inflammation and to predict steroid response. The main field of application of this biomarker is asthma, but FeNO has also been used for other allergic and non-allergic pulmonary disorders such as chronic obstructive pulmonary disease, hypersensitivity pneumonitis and interstitial lung disease. A substantial part of respiratory diseases are related to work, and FeNO, a safe and easy measure to conduct, is a potential valid examination in an occupational setting. This systematic review assesses the value of measuring FeNO related to three types of airborne exposures: allergens, irritants, and respiratory particles inhaled during occupational activities. The review covers results from longitudinal and observational clinical studies, and highlights the added value of this biomarker in monitoring effects of exposure and in the diagnostic criteria of occupational diseases. This review also covers the possible significance of FeNO as an indicator of the efficacy of interventions to prevent work-related respiratory diseases. Initially, 246 articles were identified in PUBMED and SCOPUS. Duplicates and articles which covered results from the general population, symptoms (not disease) related to work, non-occupational diseases, and case reports were excluded. Finally, 39 articles contributed to this review, which led to the following conclusions: a) For occupational asthma there is no consensus on the significant value of FeNO for diagnosis, or on the magnitude of change needed after specific inhalation test or occupational exposure at the workplace. There is some consensus for the optimal time to measure FeNO after exposure, mainly after 24 h, and FeNO proved to be more sensitive than spirometry in measuring the result of an intervention. b) For other occupational obstructive respiratory diseases, current data suggests performing the measurement after the work shift. c) For interstitial lung disease, the evaluation of the alveolar component of NO is probably the most suitable.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Arbetsmedicin och miljömedicin0 (SwePub)303032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Occupational Health and Environmental Health0 (SwePub)303032 hsv//eng
653 a Fractional exhaled nitric oxide (FeNO)
653 a Occupational asthma
653 a Occupational bronchitis
653 a Occupational interstitial lung disease
653 a Occupational hypersensitivity pneumonitis
653 a lung-function
653 a educational intervention
653 a asthma
653 a feno
653 a exposure
653 a diagnosis
653 a health
653 a breath
653 a inflammation
653 a challenge
653 a Public
653 a Environmental & Occupational Health
700a Fell, A. K. M.4 aut
700a Handra, C. M.4 aut
700a Holm, Mathias,d 1969u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xhomat
700a Filon, F. L.4 aut
700a Mijakovski, D.4 aut
700a Minov, J.4 aut
700a Mutu, A.4 aut
700a Stephanou, E.4 aut
700a Stokholm, Z. A.4 aut
700a Stoleski, S.4 aut
700a Schlunssen, V.4 aut
710a Göteborgs universitetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org
773t Journal of Occupational Medicine and Toxicologyd : Springer Science and Business Media LLCg 17:1q 17:1x 1745-6673
8564 8u https://gup.ub.gu.se/publication/317657
8564 8u https://doi.org/10.1186/s12995-022-00355-1

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