WFRF:(Al Khalili Faris)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04082naa a2200481 4500 | |
| 001 | oai:DiVA.org:liu-141557 | |
| 003 | SwePub | |
| 008 | 170929s2017 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:136823921 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1415572 URI |
| 024 | 7 | a https://doi.org/10.1093/europace/eux0022 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1368239212 URI |
| 040 | a (SwePub)liud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Aronsson, Mattias,d 1989-u Linköpings universitet,Avdelningen för hälso- och sjukvårdsanalys,Medicinska fakulteten4 aut0 (Swepub:liu)matar90 |
| 245 | 1 0 | a Designing an optimal screening program for unknown atrial fibrillation :b a cost-effectiveness analysis. |
| 264 | c 2017-03-01 | |
| 264 | 1 | a Oxford :b Oxford University Press,c 2017 |
| 338 | a print2 rdacarrier | |
| 500 | a Funding agencies: Dental and Pharmaceutical Benefits Agency | |
| 520 | a Aims: The primary objective of this study was to use computer simulations to suggest an optimal age for initiation of screening for unknown atrial fibrillation and to evaluate if repeated screening will add value.Methods and results: In the absence of relevant clinical studies, this analysis was based on a simulation model. More than two billion different designs of screening programs for unknown atrial fibrillation were simulated and analysed. Data from the published scientific literature and registries were used to construct the model and estimate lifelong effects and costs. Costs and effects generated by 2 147 483 648 different screening designs were calculated and compared. Program designs that implied worse clinical outcome and were less cost-effective compared to other programs were excluded from the analysis. Seven program designs were identified, and considered to be cost effective depending on what the health-care decision makers are ready to pay for gaining a quality-adjusted life-year (QALY). Screening at the age of 75 implied the lowest cost per gained QALY (€4 800/QALY).Conclusion: In conclusion, examining the results of more than two billion simulated screening program designs for unknown atrial fibrillation, seven designs were deemed cost-effective depending on how much we are prepared to pay for gaining QALYs. Our results showed that repeated screening for atrial fibrillation implied additional health benefits to a reasonable cost compared to one-off screening. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi0 (SwePub)303012 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Health Care Service and Management, Health Policy and Services and Health Economy0 (SwePub)303012 hsv//eng |
| 653 | a Atrial fibrillation | |
| 653 | a Cost-utility analysis | |
| 653 | a Optimization analysis | |
| 653 | a Screening | |
| 700 | 1 | a Svennberg, Emmau Karolinska Institutet4 aut |
| 700 | 1 | a Rosenqvist, Mårtenu Karolinska Institutet4 aut |
| 700 | 1 | a Engdahl, Johanu Karolinska Institutet4 aut |
| 700 | 1 | a Al-Khalili, Farisu Karolinska Institutet4 aut |
| 700 | 1 | a Friberg, Leifu Karolinska Institutet4 aut |
| 700 | 1 | a Frykman, Vivekau Karolinska Institutet4 aut |
| 700 | 1 | a Levin, Lars-Åke,d 1960-u Linköpings universitet,Avdelningen för hälso- och sjukvårdsanalys,Medicinska fakulteten4 aut0 (Swepub:liu)larle77 |
| 710 | 2 | a Linköpings universitetb Avdelningen för hälso- och sjukvårdsanalys4 org |
| 773 | 0 | t Europaced Oxford : Oxford University Pressg 19:10, s. 1650-1656q 19:10<1650-1656x 1099-5129x 1532-2092 |
| 856 | 4 | u https://academic.oup.com/europace/article-pdf/19/10/1650/20917301/eux002.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-141557 |
| 856 | 4 8 | u https://doi.org/10.1093/europace/eux002 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:136823921 |
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