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Sökning: WFRF:(Bartoletti A) > Recurrence, progres...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006049naa a2200685 4500
001oai:DiVA.org:uu-366942
003SwePub
008181128s2018 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3669422 URI
024a https://doi.org/10.1007/s00345-018-2299-22 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Palou, J.u Univ Barcelona, Dept Urol, Fundacio Puigvert, Barcelona, Spain4 aut
2451 0a Recurrence, progression and cancer-specific mortality according to stage at re-TUR in T1G3 bladder cancer patients treated with BCG :b not as bad as previously thought
264 c 2018-05-02
264 1b SPRINGER,c 2018
338 a print2 rdacarrier
520 a Purpose: The goals of transurethral resection of a bladder tumor (TUR) are to completely resect the lesions and to make a correct diagnosis to adequately stage and treat the patient. Persistent disease after TUR is not uncommon and is why re-TUR is recommended in T1G3 patients. When there is T1 tumor in the re-TUR specimen, very high risks of progression (82%) have been reported. We analyze the risks of recurrence, progression to muscle-invasive disease and cancer-specific mortality (CSM) according to tumor stage at re-TUR in T1G3 patients treated with BCG.Methods: In our retrospective cohort of 2451 T1G3 patients, 934 patients (38.1%) underwent re-TUR. 667 patients had residual disease (71.4%): Ta in 378 (40.5%), T1 in 289 (30.9%) patients. Times to recurrence, progression and CSM in the three groups were estimated using cumulative incidence functions and compared using the Cox regression model.Results:During a median follow-up of 5.2years, 512 patients recurred. The recurrence rate was significantly higher in patients with a T1 at re-TUR (P<0.001). Progression rates differed according to the pathology at re-TUR, 25.3% in T1, 14.6% in Ta and 14.2% in case of no residual tumor (P<0.001). Similar trends were seen in both patients with and without muscle in the original TUR specimen.Conclusions: Patients with T1G3 tumors and no residual disease or Ta at re-TUR have better recurrence, progression and CSM rates than previously reported, with a CSM rate of 13.1 and a 25.3% progression rate in re-TUR T1 disease.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng
653 a Non-muscle invasive bladder cancer
653 a Re-transurethral resection of the bladder
653 a Recurrence
653 a Progression
700a Pisano, F.u Univ Barcelona, Dept Urol, Fundacio Puigvert, Barcelona, Spain;Osped Citta Salute & Sci Molinette, Dept Urol, Corso Bramante 88, I-10126 Turin, Italy4 aut
700a Sylvester, R.u EORTC Headquarters, Dept Biostat, Brussels, Belgium4 aut
700a Joniau, S.u Univ Hosp Leuven, Oncol & Reconstruct Urol, Dept Urol, Louvain, Belgium4 aut
700a Serretta, V.u Univ Palermo, Dept Surg Oncol & Stomatol Sci, Palermo, Italy4 aut
700a Larre, S.u Univ Oxford, John Radcliffe Hosp, Dept Surg Sci, Oxford, England4 aut
700a Di Stasi, S.u Policlin Tor Vergata Univ Rome, Rome, Italy4 aut
700a van Rhijn, B.u Antoni van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Urol, Amsterdam, Netherlands4 aut
700a Witjes, A. J.u Radboud Univ Nijmegen, Med Ctr, Dept Urol, Nijmegen, Netherlands4 aut
700a Grotenhuis, A.u Radboud Univ Nijmegen, Med Ctr, Dept Urol, Nijmegen, Netherlands4 aut
700a Colombo, R.u Univ Vita Salute, Osped S Raffaele, Dipartimento Urol, Milan, Italy4 aut
700a Briganti, A.u Univ Vita Salute, Osped S Raffaele, Dipartimento Urol, Milan, Italy4 aut
700a Babjuk, M.u Univ Praha, Motol Hosp, Dept Urol, Prague, Czech Republic4 aut
700a Soukup, V.u Univ Praha, Motol Hosp, Dept Urol, Prague, Czech Republic4 aut
700a Malmström, Per-Unou Uppsala universitet,Urologkirurgi4 aut0 (Swepub:uu)perunoms
700a Irani, J.u Univ Poitiers, Dept Urol, Ctr Hosp Univ Mil, Poitiers, France4 aut
700a Malats, N.u Spanish Natl Canc Res Ctr CNIO, Genet & Mol Epidemiol Grp, Madrid, Spain4 aut
700a Baniel, J.u Rabin Med Ctr, Dept Urol, Tel Aviv, Israel4 aut
700a Mano, R.u Rabin Med Ctr, Dept Urol, Tel Aviv, Israel4 aut
700a Cai, T.u Santa Chiara Hosp, Dept Urol, Trento, Italy4 aut
700a Cha, E. K.u Cornell Univ, Weill Med Coll, Dept Urol, New York, NY 10021 USA4 aut
700a Ardelt, P.u Chirurg Univ Klin, Facharzt Urol, Urol Abt, Freiburg, Germany4 aut
700a Varkarakis, J.u Univ Athens, Sismanoglio Hosp, Dept Urol, Athens, Greece4 aut
700a Bartoletti, R.u Univ Florence, Dept Expt & Clin Med, Florence, Italy4 aut
700a Dalbagni, G.u Mem Sloan Kettering Canc Ctr, Dept Urol, 1275 York Ave, New York, NY 10021 USA4 aut
700a Shariat, S. F.u Med Univ Vienna, Vienna, Austria4 aut
700a Xylinas, E.u Cochin Hosp, Dept Urol, Paris, France4 aut
700a Karnes, R. J.u Mayo Clin, Dept Urol, Rochester, MN USA4 aut
700a Gontero, P.u Osped Citta Salute & Sci Molinette, Dept Urol, Corso Bramante 88, I-10126 Turin, Italy4 aut
710a Univ Barcelona, Dept Urol, Fundacio Puigvert, Barcelona, Spainb Univ Barcelona, Dept Urol, Fundacio Puigvert, Barcelona, Spain;Osped Citta Salute & Sci Molinette, Dept Urol, Corso Bramante 88, I-10126 Turin, Italy4 org
773t World journal of urologyd : SPRINGERg 36:10, s. 1621-1627q 36:10<1621-1627x 0724-4983x 1433-8726
856u https://art.torvergata.it/bitstream/2108/213079/1/World%20Journal%20of%20Urology%202018_36_1621_1627.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-366942
8564 8u https://doi.org/10.1007/s00345-018-2299-2

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