WFRF:(Blessborn Daniel)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02931naa a2200361 4500 | |
| 001 | oai:dalea.du.se:1619 | |
| 003 | SwePub | |
| 008 | 051221s2006 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-108744 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:du-16192 URI |
| 024 | 7 | a https://doi.org/10.1016/j.jpba.2005.10.0182 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1087442 URI |
| 040 | a (SwePub)dud (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Blessborn, Danielu Högskolan Dalarna,Kemiteknik,Dalarna University College, S-781 88 Borlänge, Sweden4 aut0 (Swepub:du)dbl |
| 245 | 1 0 | a A new approach to evaluate stability of amodiaquine and its metabolite in blood and plasma |
| 264 | 1 | b Elsevier BV,c 2006 |
| 338 | a print2 rdacarrier | |
| 520 | a A stability study for amodiaquine (AQ) and desethylamodiaquine (AQm) in whole blood and plasma is reported. AQ, AQm and chloroquine (CQ) were simultaneously analysed and the ratios AQ/CQ and AQm/CQ were used to ensure correct interpretation of the stability results. CQ was stable in whole blood and plasma at all tested temperatures enabling it to be a stability marker in stability studies. Simultaneous analysis of compounds, of which at least one is already known to be stable, permits a within sample ratio to be used as a stability indicator, The new approach significantly reduced bias when compared to the traditional approach. AQ and AQm were stable in plasma at -86 degrees C and -20 degrees C for 35 days, at 4 degrees C for 14 days and at 22 degrees C for 1 day. AQ and AQm were stable in blood at -86 degrees C and 4 degrees C for 35 days, at -20 degrees C and 22 degrees C for 7 days and at 37 degrees C for 1 day. | |
| 650 | 7 | a NATURVETENSKAPx Kemi0 (SwePub)1042 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciences0 (SwePub)1042 hsv//eng |
| 653 | a antimalarial; amoditiquine; chloroquine; desethylamodiaquine; liquid chromatography; solid-phase extraction; stability | |
| 700 | 1 | a Neamin, G.u Dalarna University College, S-781 88 Borlänge, Sweden4 aut |
| 700 | 1 | a Bergqvist, Yngveu Högskolan Dalarna,Kemiteknik,Dalarna University College, S-781 88 Borlänge, Sweden4 aut0 (Swepub:du)ybq |
| 700 | 1 | a Lindegårdh, N.u Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand. Nuffield Department of Clinical Medicine, Centre for Tropical Medicine, University of Oxford, Oxford, UK4 aut |
| 710 | 2 | a Högskolan Dalarnab Kemiteknik4 org |
| 773 | 0 | t Journal of Pharmaceutical and Biomedical Analysisd : Elsevier BVg 41:1, s. 207-212q 41:1<207-212x 0731-7085x 1873-264X |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:du-1619 |
| 856 | 4 8 | u https://doi.org/10.1016/j.jpba.2005.10.018 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108744 |
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