Adherence to treatment in allergic rhinitis using mobile technology: The MASK Study

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MARC

Menditto, EnricaCIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; University of Naples Federico II, Naples, Italy (author)

Adherence to treatment in allergic rhinitis using mobile technology : The MASK Study

Article/chapterEnglish2019

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2019-03-12
WILEY,2019
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LIBRIS-ID:oai:DiVA.org:umu-162486
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-162486URI
https://doi.org/10.1111/cea.13333DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-373947URI
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158062URI
http://kipublications.ki.se/Default.aspx?queryparsed=id:140678208URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

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Background: Mobile technology may help to better understand the adherence to treatment. MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centred ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. Objectives: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. Methods: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from 1 January 2016 to 1 August 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. Results: A total of 12143 users were registered. A total of 6949 users reported at least one VAS data recording. Among them, 1887 users reported >= 7 VAS data. About 1195 subjects were included in the analysis of adherence. One hundred and thirty-six (11.28%) users were adherent (MPR >= 70% and PDC <= 1.25), 51 (4.23%) were partly adherent (MPR >= 70% and PDC = 1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR <70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. Conclusion and clinical relevance: Adherence to treatment is low. The relative efficacy of continuous vs on-demand treatment for allergic rhinitis symptoms is still a matter of debate. This study shows an approach for measuring retrospective adherence based on a mobile app. This also represents a novel approach for analysing medication-taking behaviour in a real-world setting.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Samhällsfarmaci och klinisk farmaci hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Social and Clinical Pharmacy hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Lungmedicin och allergi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Respiratory Medicine and Allergy hsv//eng
adherence
mHealth
mobile technology
observational study
rhinitis
treatment

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Bosnic-Anticevich, SinthiaWoolcock Institute of Medical Research, University of Sydney Woolcock Emphysema Centre and Sydney Local Health District, Glebe, NSW, Australia (author)
Novellino, EttoreUniversity of Naples Federico II, Naples, Italy (author)
Bialek, SlawomirDepartment of Biochemistry and Clinical Chemistry, Faculty of Pharmacy with the Division of Laboratory Medicine, Warsaw Medical University, Warsaw, Poland (author)
Briedis, VitalisLithuanian University of Health Sciences, Kaunas, Lithuania (author)
Mair, AlpanaDG for Health and Social Care, Scottish Government, Edinburgh, United Kingdom,Allergy Unit, CUF-Porto Hospital and Institute, Porto, Portugal; Center for Research in Health Technologies and Information Systems CINTESIS, Universidade do Porto, Porto, Portugal,Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal (author)
Rajabian-Soderlund, RojinDepartment of Nephrology and Endocrinology, Karolinska University Hospital, Stockholm, Sweden (author)
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Anto, Josep M.ISGlobAL, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; IMIM (Hospital del Mar Research Institute), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain,Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal; Ageing@Coimbra EIP-AHA Reference Site, Coimbra, Portugal,Rhinology Unit and Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain; Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain (author)
Devillier, PhilippeLaboratoire de Pharmacologie Respiratoire UPRES EA220, Hôpital Foch, Suresnes, France; Université Versailles Saint-Quentin, Université Paris Saclay, Paris Saclay, France (author)
De Vries, GovertPeercode BV, Geldermalsen, Netherlands (author)
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Sheikh, AzizThe Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, United Kingdom (author)
Orlando, ValentinaCIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; University of Naples Federico II, Naples, Italy (author)
Larenas-Linnemann, DesireeCenter of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico (author)
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De Feo, GiuliaDepartment of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy (author)
Illario, M.Division for Health Innovation, Campania Region and Federico II University Hospital Naples (RandD and DISMET), Naples, Italy (author)
Stellato, CristianaDepartment of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy (author)
Fonseca, JoaoCINTESIS, Center for Research in Health Technologies and Information Systems, Faculdade de Medicina da Universidade do Porto, Porto, Portugal; MEDIDA, Lda, Porto, Portugal,Allergist, Reims, France (author)
Malva, Joao (author)
Morais-Almeida, MarioAllergy Center, CUF Descobertas Hospital, Lisbon, Portugal (author)
Pereira, Ana Maria (author)
Todo-Bom, Ana Maria (author)
Kvedariene, VioletaFaculty of Medicine, Vilnius University, Vilnius, Lithuania (author)
Valiulis, ArunasDepartment of Public Health, Clinic of Childrens Diseases, and Institute of Health Sciences, Vilnius University Institute of Clinical Medicine, Vilnius, Lithuania; European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium (author)
Bergmann, Karl ChristianCharité – Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany (author)
Klimek, LudgerEuforea, Brussels, Belgium (author)
Moesges, RalphMedical Faculty, Institute of Medical Statistics, and Computational Biology, University of Cologne, Cologne, Germany; CRI-Clinical Research International-Ltd, Hamburg, Germany (author)
Pfaar, OliverDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Phillipps-Universität Marburg, Germany (author)
Zuberbier, TorstenCharité – Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany (author)
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Papadopoulos, Nikos G.Division of Infection, Immunityand Respiratory Medicine, Royal Manchester Childrens Hospital, University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Pediatric Clinic, Athens General Childrens Hospital “PandA Kyriakou”, University of Athens, Athens, Greece (author)
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Verissimo, M. T. (author)
Viart, F. (author)
Viegi, G. (author)
Vicheva, D. (author)
Vontetsianos, T. (author)
Wagenmann, M. (author)
Walker, S. (author)
Wallace, D. (author)
Wang, D. Y. (author)
Waserman, S. (author)
Werfel, T. (author)
Westman, M. (author)
Wickman, M. (author)
Williams, D. M. (author)
Williams, S. (author)
Wilson, N. (author)
Wright, J. (author)
Wroczynski, P. (author)
Yakovliev, P. (author)
Yawn, B. P. (author)
Yiallouros, P. K. (author)
Yorgancioglu, A. (author)
Yusuf, O. M. (author)
Zar, H. J. (author)
Zhang, L. (author)
Zhong, N. (author)
Zernotti, M. E. (author)
Zhanat, I. (author)
Zidarn, M. (author)
Zuberbier, T. (author)
Zubrinich, C. (author)
Zurkuhlen, A. (author)
CIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; University of Naples Federico II, Naples, ItalyUCIBIO, REQUIMTE, Faculty of Pharmacy, and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing), University of Porto, Porto, Portugal (creator_code:org_t)

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In:Clinical and Experimental Allergy: WILEY49:4, s. 442-4600954-78941365-2222

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By the author/editor: Menditto, Enrica; Costa, Elisio; Midao, Luis; Bosnic-Anticevic ...; Novellino, Ettor ...; Bialek, Slawomir; show more...; Briedis, Vitalis; Mair, Alpana; Rajabian-Soderlu ...; Arnavielhe, Sylv ...; Bedbrook, Anna; Czarlewski, Wien ...; Annesi-Maesano, ...; Anto, Josep M.; Devillier, Phili ...; De Vries, Govert; Keil, Thomas; Sheikh, Aziz; Orlando, Valenti ...; Larenas-Linneman ...; Cecchi, Lorenzo; De Feo, Giulia; Illario, M.; Stellato, Cristi ...; Fonseca, Joao; Malva, Joao; Morais-Almeida, ...; Pereira, Ana Mar ...; Todo-Bom, Ana Ma ...; Kvedariene, Viol ...; Valiulis, Arunas; Bergmann, Karl C ...; Klimek, Ludger; Moesges, Ralph; Pfaar, Oliver; Zuberbier, Torst ...; Cardona, Vicky; Mullol, Joaquim; Papadopoulos, Ni ...; Prokopakis, Emma ...; Bewick, Mike; Ryan, Dermot; Roller-Wirnsberg ...; Tomazic, Peter V ...; Cruz, Alvaro A.; Kuna, Piotr; Samolinski, Bole ...; Fokkens, Wytske ...; Reitsma, Sietze; Bosse, Isabelle; Fontaine, Jean-F ...; Laune, Daniel; Haahtela, Tari; Toppila-Salmi, S ...; Bachert, Claus; Hellings, Peter ...; Melen, Erik; Wickman, Magnus; Bindslev-Jensen, ...; Eller, Esben; O'Hehir, Robyn E ...; Cingi, Cemal; Gemicioglu, Bilu ...; Kalayci, Omer; Ivancevich, Juan ...; Bousquet, Jean; Bousquet, J.; Hellings, P. 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L.; Kuitunen, M.; Kull, I.; Kuna, P.; Kupczyk, M.; Kvedariene, V.; Krzych-Falta, E.; Lacwik, P.; Larenas-Linneman ...; Laune, D.; Lauri, D.; Lavrut, J.; Le, L. T. T.; Lessa, M.; Levato, G.; Li, J.; Lieberman, P.; Liplec, A.; Lipworth, B.; Carlsen, K. C. L ...; Louis, R.; Lourenco, O.; Luna-Pech, J. A.; Magnan, A.; Mahboub, B.; Maier, D.; Mair, A.; Majer, I.; Malva, J.; Mandajieva, E.; Manning, P.; Keenoy, E. De Ma ...; Marshall, G. D.; Masjedi, M. R.; Maspero, J. F.; Mathieu-Dupas, E ...; Campos, J. J. Ma ...; Matos, Al; Maurer, M.; Mavale-Manuel, S ...; Mayora, O.; Medina-Avalos, M ...; Melen, E.; Melo-Gomes, E.; Meltzer, Eo; Menditto, E.; Mercier, J.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Moda, G.; Mogica-Martinez, ...; Mohammad, Y.; Momas, I.; Monte-Fort, S.; Monti, R.; Bogado, D. Mora; Morais-Almeida, ...; Mosges, R.; Mota-Pinto, A.; Santo, P. 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Rod ...; Rodriguez-Manas, ...; Rolland, C.; Valle, S. Rodrig ...; Rodriguez, M. Ro ...; Romano, A.; Rodriguez-Zagal, ...; Rolla, G.; Roller-Wirnsberg ...; Romano, M.; Rosado-Pinto, J.; Rosario, N.; Rottem, M.; Ryan, D.; Sagara, H.; Salimaki, J.; Samolinski, B.; Sanchez-Borges, ...; Sastre-Dominguez ...; Scadding, G. K.; Schunemann, H. J ...; Scichilone, N.; Schmid-Grendelme ...; Serpa, F. S.; Shamai, S.; Sheikh, A.; Sierra, M.; Simons, F. E. R.; Sir-Oux, V.; Sisul, J. C.; Skrindo, I.; Sole, D.; Somekh, D.; Sonder-Mann, M.; Sooronbaev, T.; Sova, M.; Sorensen, M.; Sorlini, M.; Spranger, O.; Stellato, C.; Stelmach, R.; Stukas, R.; Sunyer, J.; Strozek, J.; Szylling, A.; Tebyrica, Jn; Thibaudon, M.; To, T.; Todo-Bom, A.; Tomazic, P. V.; Toppila-Salmi, S ...; Trama, U.; Triggiani, M.; Ulrik, C. Suppli; Urrutia-Pereira, ...; Valenta, R.; Valero, A.; Valiulis, A.; Valovirta, E.; Van Eerd, M.; Van Ganse, E.; Van Hague, M.; Vandenplas, O.; Ventura, M. T.; Vezzani, G.; Vasankari, T.; Vatrella, A.; Verissimo, M. T.; Viart, F.; Viegi, G.; Vicheva, D.; Vontetsianos, T.; Wagenmann, M.; Walker, S.; Wallace, D.; Wang, D. Y.; Waserman, S.; Werfel, T.; Westman, M.; Wickman, M.; Williams, D. M.; Williams, S.; Wilson, N.; Wright, J.; Wroczynski, P.; Yakovliev, P.; Yawn, B. P.; Yiallouros, P. K ...; Yorgancioglu, A.; Yusuf, O. M.; Zar, H. J.; Zhang, L.; Zhong, N.; Zernotti, M. E.; Zhanat, I.; Zidarn, M.; Zuberbier, T.; Zubrinich, C.; Zurkuhlen, A.; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Social and Clini ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Respiratory Medi ...

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