WFRF:(Johansson Anna L.V.)
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Mortality in women with pregnancy-associated malignant melanoma
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- Johansson, Anna L. V. (författare)
- Karolinska Institutet
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- Andersson, Therese M-L. (författare)
- Karolinska Institutet
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- Plym, Anna (författare)
- Karolinska Institutet
- visa fler...
- Moller, Henrik (författare)
- Lambe, Mats (författare)
- visa färre...
- (creator_code:org_t)
- Elsevier BV, 2014
- 2014
- Engelska.
- Ingår i: The Journal of American Academy of Dermatology. - : Elsevier BV. - 0190-9622 .- 1097-6787. ; 71:6, s. 1093-1101
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
Stäng
- Background: Malignant melanoma (MM) is one of the most common malignancies in young women. It remains debated whether a MM diagnosed during pregnancy or lactation has a worse prognosis. Objective: We sought to examine mortality in women with pregnancy-associated MM (PAMM) (diagnosed during pregnancy and up to 2-years postpartum). Methods: This was a population-based cohort study based on information retrieved from the Swedish Cancer and Multi-Generation Registers. Hazard ratios with 95% confidence intervals adjusted for age, period, education, parity, and tumor location were estimated. Results: In total, 6857 women and girls aged 15 to 44 years with a diagnosis of cutaneous MM between 1963 and 2009 were identified. Of these, 1019 cases were classified as PAMM. The cause-specific mortality did not differ between PAMM and MM not diagnosed near childbirth (adjusted hazard ratio 1.09, 95% confidence interval 0.83-1.42). Limitations: Information on stage at diagnosis was available only for a subset of patients Conclusion: Overall, the cause-specific mortality in women and girls with PAMM did not differ from that in women and girls with non-PAMM. The current findings do not provide evidence of an adverse prognostic influence of pregnancy or a recent birth.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- malignant melanoma
- mortality
- pregnancy
- stage
- survival
- Sweden
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Plym, Anna
- Ullenhag, Gustav ...
- Moller, Henrik
- Lambe, Mats
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