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Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs

Bell, Jane C. (författare)
Children's Hospital At Westmead,University of Sydney
Baynam, Gareth (författare)
University of Western Australia, Perth,Government of Western Australia
Bergman, Jorieke E.H. (författare)
University Medical Center Groningen,University of Groningen
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Bermejo-Sánchez, Eva (författare)
Carlos III Health Institute
Botto, Lorenzo D. (författare)
University of Utah
Canfield, Mark A. (författare)
Texas Department of State Health Services
Dastgiri, Saeed (författare)
Tabriz University of Medical Sciences
Gatt, Miriam (författare)
Directorate for Health Information and Research
Groisman, Boris (författare)
National Center of Medical Genetics (CENAGEM)
Hurtado-Villa, Paula (författare)
Pontificia Universidad Javeriana, Cali
Kallen, Karin (författare)
Lund University,Lunds universitet,Miljöepidemiologi,Forskargrupper vid Lunds universitet,Environmental Epidemiology,Lund University Research Groups
Khoshnood, Babak (författare)
Centre of Epidemiology And Biostatistics Sorbonne Paris Cité Center (CRESS)
Konrad, Victoria (författare)
Centers For Disease Control And Prevention
Landau, Danielle (författare)
Soroka Medical Center
Lopez-Camelo, Jorge S. (författare)
Centro De Educacion Medica e Investigaciones Clinicas Norberto Quirno Escuela de Medicina (ECLAMC)
Martinez, Laura (författare)
Universidad Autonoma de Nuevo Leon
Morgan, Margery (författare)
Singleton Hospital
Mutchinick, Osvaldo M. (författare)
Instituto Nacional de Ciencias Médicas y Nutrición
Nance, Amy E. (författare)
Utah Department of Health
Nembhard, Wendy (författare)
University of Arkansas for Medical Sciences
Pierini, Anna (författare)
Gabriele Monasterio Foundation,CNR Institute of Clinical Physiology (IFC-CNR)
Rissmann, Anke (författare)
University Hospital Magdeburg
Shan, Xiaoyi (författare)
Arkansas Children's Hospital
Sipek, Antonin (författare)
Thomayer Hospital
Szabova, Elena (författare)
Slovak Medical University
Tagliabue, Giovanna (författare)
Istituto Nazionale dei Tumori
Yevtushok, Lyubov S. (författare)
Rivne Regional Medical Diagnostic Center,Omni-Net for Children International Charitable Fund Rivne
Zarante, Ignacio (författare)
Pontificia Universidad Javeriana
Nassar, Natasha (författare)
University of Sydney
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 (creator_code:org_t)
2021-03-18
2021
Engelska.
Ingår i: Birth Defects Research. - : Wiley. - 2472-1727. ; 113:12, s. 945-957
Relaterad länk:
http://dx.doi.org/10...
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https://pure.rug.nl/...
https://lup.lub.lu.s...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Background: Esophageal atresia (EA) affects around 2.3–2.6 per 10,000 births world-wide. Infants born with this condition require surgical correction soon after birth. Most survival studies of infants with EA are locally or regionally based. We aimed to describe survival across multiple world regions. Methods: We included infants diagnosed with EA between 1980 and 2015 from 24 birth defects surveillance programs that are members of the International Clearinghouse for Birth Defects Surveillance and Research. We calculated survival as the proportion of liveborn infants alive at 1 month, 1- and 5-years, among all infants with EA, those with isolated EA, those with EA and additional anomalies or EA and a chromosomal anomaly or genetic syndrome. We also investigated trends in survival over the decades, 1980s–2010s. Results: We included 6,466 liveborn infants with EA. Survival was 89.4% (95% CI 88.1–90.5) at 1-month, 84.5% (95% CI 83.0–85.9) at 1-year and 82.7% (95% CI 81.2–84.2) at 5-years. One-month survival for infants with isolated EA (97.1%) was higher than for infants with additional anomalies (89.7%) or infants with chromosomal or genetic syndrome diagnoses (57.3%) with little change at 1- and 5-years. Survival at 1 month improved from the 1980s to the 2010s, by 6.5% for infants with isolated EA and by 21.5% for infants with EA and additional anomalies. Conclusions: Almost all infants with isolated EA survived to 5 years. Mortality was higher for infants with EA and an additional anomaly, including chromosomal or genetic syndromes. Survival improved from the 1980s, particularly for those with additional anomalies.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Nyckelord

congenital anomalies
esophageal atresia
infant
mortality
survival

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