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FältnamnIndikatorerMetadata
00010004naa a2200973 4500
001oai:DiVA.org:uu-454577
003SwePub
008211001s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4545772 URI
0247 a https://doi.org/10.1038/s41409-019-0684-02 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Sharrack, Basilu Sheffield Teaching Hosp NHS Fdn Trust, Dept Neurol, Sheffield, S Yorkshire, England.;Univ Sheffield, NIHR Neurosci Biomed Res Ctr, Sheffield, S Yorkshire, England.4 aut
2451 0a Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases :b updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE)
264 c 2019-09-26
264 1b Springer Nature,c 2020
338 a electronic2 rdacarrier
520 a These updated EBMT guidelines review the clinical evidence, registry activity and mechanisms of action of haematopoietic stem cell transplantation (HSCT) in multiple sclerosis (MS) and other immune-mediated neurological diseases and provide recommendations for patient selection, transplant technique, follow-up and future development. The major focus is on autologous HSCT (aHSCT), used in MS for over two decades and currently the fastest growing indication for this treatment in Europe, with increasing evidence to support its use in highly active relapsing remitting MS failing to respond to disease modifying therapies. aHSCT may have a potential role in the treatment of the progressive forms of MS with a significant inflammatory component and other immune-mediated neurological diseases, including chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, myasthenia gravis and stiff person syndrome. Allogeneic HSCT should only be considered where potential risks are justified. Compared with other immunomodulatory treatments, HSCT is associated with greater short-term risks and requires close interspeciality collaboration between transplant physicians and neurologists with a special interest in these neurological conditions before, during and after treatment in accredited HSCT centres. Other experimental cell therapies are developmental for these diseases and patients should only be treated on clinical trials.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
7001 a Saccardi, Riccardou Careggi Univ Hosp, Cell Therapy & Transfus Med Unit, Florence, Italy.;Careggi Univ Hosp, Haematol Dept, Florence, Italy.4 aut
7001 a Alexander, Tobiasu Charite, Klin Rheumatol & Klin Immunol, Berlin, Germany.4 aut
7001 a Badoglio, Manuelau Sorbonne Univ, St Antoine Hosp, Dept Haematol, INSERM UMR 938,EBMT Paris Study Off, Paris, France.4 aut
7001 a Burman, Joachim,d 1974-u Uppsala universitet,Landtblom: Neurovetenskap4 aut0 (Swepub:uu)joabu293
7001 a Farge, Dominiqueu Hop St Louis, AP HP, Unite Med Interne Malad Autoimmunes & Pathol Vasc, Paris, France.;FAI2R, Ctr Reference Malad Autoimmunes Syst Rares Ile de, Filiere, Paris, France.;Univ Paris 07, EA 3518, Paris, France.;McGill Univ, Dept Internal Med, Montreal, PQ, Canada.4 aut
7001 a Greco, Raffaellau Ist Sci San Raffaele, Hematol & Bone Marrow Transplantat Unit, IRCCS, Milan, Italy.4 aut
7001 a Jessop, Helenu Sheffield Teaching Hosp NHS Fdn Trust, Dept Haematol, Sheffield, S Yorkshire, England.4 aut
7001 a Kazmi, Majidu Guys Hosp, Dept Haematol, Kings Hlth Partners, London, England.4 aut
7001 a Kirgizov, Kirillu Inst Pediat Oncol & Hematol, NN Blokhin Natl Med Ctr Oncol, Moscow, Russia.4 aut
7001 a Labopin, Myriamu Sorbonne Univ, St Antoine Hosp, Dept Haematol, INSERM UMR 938,EBMT Paris Study Off, Paris, France.4 aut
7001 a Mancardi, Gianluigiu Univ Genoa, Dept Neurosci, Genoa, Italy.;Clin Sci Inst Maugeri, Genoa, Italy.4 aut
7001 a Martin, Rolandu Univ Hosp, Neurol Clin, Neuroimmunol & MS Res, Zurich, Switzerland.4 aut
7001 a Moore, Johnu St Vincents Hlth Network, Haematol Dept, Darlinghurst, NSW, Australia.4 aut
7001 a Muraro, Paolo A.u Imperial Coll London, Dept Brain Sci, London, England.4 aut
7001 a Rovira, Montserratu Hosp Clin Barcelona, Inst Josep Carreras, Dept Hematol, BMT Unit, Barcelona, Spain.;Hosp Clin Barcelona, Inst Josep Carreras, Dept Hematol, BMT Unit,IDIBAPS, Barcelona, Spain.4 aut
7001 a Sormani, Maria Piau Univ Genoa, Dept Hlth Sci DISSAL, Genoa, Italy.;IRCCS Osped Policlin San Martino, Genoa, Italy.4 aut
7001 a Snowden, John A.u Sheffield Teaching Hosp NHS Fdn Trust, Dept Haematol, Sheffield, S Yorkshire, England.4 aut
7001 a Snowden, Johnu Sheffield Teaching Hosp NHS Fdn Trust, Dept Haematol, Sheffield, S Yorkshire, England.4 aut
7001 a McGrath, Eoinu EBMT Execut Off, Barcelona, Spain.4 aut
7001 a Bambi, Francou Azienda Osped Univ Meyer AOU Meyer, Osped Pediat, Florence, Italy.4 aut
7001 a Sanchez-Guijo, Ferminu Hosp Univ Salamanca, IBSAL, Salamanca, Spain.4 aut
7001 a Worel, Ninau Med Univ Vienna, Blood Grp Serol & Transfus Med, Vienna, Austria.4 aut
7001 a Badolglio, Manuelau Sorbonne Univ, St Antoine Hosp, Dept Haematol, INSERM UMR 938,EBMT Paris Study Off, Paris, France.4 aut
7001 a Abinun, Mariou Newcastle Univ, Great North Childrens Hosp, Inst Cellular Med, Newcastle Upon Tyne, Tyne & Wear, England.4 aut
7001 a Arnold, Renateu Charit Univ Med Berlin, Dept Haematol Oncol & Tumor Immunol, Berlin, Germany.4 aut
7001 a Brierley, Charlotteu Oxford Univ Hosp NHS Fdn Trust, Dept Haematol, Oxford, England.4 aut
7001 a Castilla-Llorente, Cristinau Dept Hematol Gustave Roussy, Unit Transplantat Cellules Souches, Villejuif, France.4 aut
7001 a Cooper, Nicholau Imperial Coll Hlth Care NHS Trust, Hammersmith Hosp, Dept Haematol, London, England.4 aut
7001 a Daikeler, Thomasu Univ Basel, Dept Rheumatol, Basel, Switzerland.;Univ Hosp Basel, Dept Rheumatol, Basel, Switzerland.4 aut
7001 a del Papa, Nicolettau Osp G Pini, Dept Rheumatol, Milan, Italy.4 aut
7001 a Finke, Jurgenu Univ Freiburg, Dept Med Hematol & Oncol, Freiburg, Germany.4 aut
7001 a Hägglund, Hansu Uppsala universitet,Hematologi4 aut0 (Swepub:uu)hanha689
7001 a Henes, Joergu Univ Hosp Tuebingen, Ctr Interdisciplinary Clin Immunol Rheumatol & Au, Dept Internal Med Oncol Oncol Haematol Immunol Rh, Tubingen, Germany.4 aut
7001 a Hiepe, Falku Charite, Klin Rheumatol & Klin Immunol, Berlin, Germany.4 aut
7001 a Kiely, Davidu Sheffield Teaching Hosp NHS Fdn Trust, Sheffield Pulm Vasc Dis Unit, Sheffield, S Yorkshire, England.4 aut
7001 a Marjanovic, Zorau St Antoine Hosp, Dept Haematol, Paris, France.4 aut
7001 a Martin, Thierryu Strasbourg Univ Hosp, Natl Referral Ctr Autoimmune Dis, Dept Clin Immunol, Strasbourg, France.4 aut
7001 a Ma, Davidu St Vincents Hlth Network, Haematol Dept, Darlinghurst, NSW, Australia.4 aut
7001 a Miller, Paulu Anthony Nolan Res Inst, London, England.4 aut
7001 a Muraro, Paolou Imperial Coll London, Dept Brain Sci, London, England.4 aut
7001 a Oliveira, Maria-Carolinau Univ Sao Paulo, Ribeirao Preto Med Sch, Div Clin Immunol, Ribeirao Preto, Brazil.4 aut
7001 a Polushin, Alexeyu First State Pavlov Med Univ St Petersburg, Raisa Gorbacheva Mem Res Inst Pediat Oncol Hemato, St Petersburg 197022, Russia.4 aut
7001 a Onida, Francescou Univ Milan, Haematol BMT Ctr, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy.4 aut
7001 a Simoes, Belindau Univ Sao Paulo, Ribeirao Preto Med Sch, Div Hematol, Ribeirao Preto, Brazil.4 aut
7001 a Puyade, Mathieuu CHU Poitiers, Poitiers, France.4 aut
7001 a Resnick, Igoru Univ Hosp St Marina, Varna 9010, Bulgaria.4 aut
7001 a Saif, Muhammadu Manchester Royal Infirm, Dept Clin Haematol, Manchester, Lancs, England.4 aut
7001 a Sakellari, Ioannau George Papanicolaou Gen Hosp, Bone Marrow Transplantat Unit, Thessaloniki, Greece.4 aut
7001 a Snarski, Emilianu Med Univ Warsaw, Dept Hematol Oncol & Internal Med, Warsaw, Poland.4 aut
7001 a Scherer, Hans Ulrichu Leiden Univ, Dept Rheumatol, Med Ctr, Leiden, Netherlands.4 aut
7001 a Sossa, Claudiau Clin FOSCAL, Hematol & Stem Cell Transplantat Unit, Div Hematol & Hematopoiet Stem Cell Transplantat, Bucaramanga, Colombia.4 aut
7001 a de Vries-Bouwstra, Jeskau Leiden Univ, Dept Rheumatol, Med Ctr, Leiden, Netherlands.4 aut
7001 a Wulffraat, Nicou Wilhelmina Childrens Hosp, Div Kinderen Cluster Immunol Reumatol Hematol Inf, Utrecht, Netherlands.4 aut
7001 a Zaccara, Eleanorau Osp G Pini, Dept Rheumatol, Milan, Italy.4 aut
7102 a Sheffield Teaching Hosp NHS Fdn Trust, Dept Neurol, Sheffield, S Yorkshire, England.;Univ Sheffield, NIHR Neurosci Biomed Res Ctr, Sheffield, S Yorkshire, England.b Careggi Univ Hosp, Cell Therapy & Transfus Med Unit, Florence, Italy.;Careggi Univ Hosp, Haematol Dept, Florence, Italy.4 org
7730 t Bone Marrow Transplantationd : Springer Natureg 55:2, s. 283-306q 55:2<283-306x 0268-3369x 1476-5365
8564 u https://doi.org/10.1038/s41409-019-0684-0y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1599539/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://www.nature.com/articles/s41409-019-0684-0.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-454577
8564 8u https://doi.org/10.1038/s41409-019-0684-0

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