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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002845naa a2200445 4500
001oai:DiVA.org:uu-262011
003SwePub
008150907s2015 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2620112 URI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Ahlgrim, C.4 aut
2451 0a Comparison of Molecular Multiplex and Singleplex Analysis of IgE to Grass Pollen Allergens in Untreated German Grass Pollen-Allergic Patients
264 1c 2015
338 a print2 rdacarrier
520 a Background: The ImmunoCAP ISAC 112 platform is the only commercially available molecular allergy IgE multiplex test. Data on the comparison of this rather novel test with the molecular singleplex ImmunoCAP IgE platform are lacking. Objective:To compare the multiplex ISAC 112 platform and the singleplex ImmunoCAP platform in regard to IgE to grass pollen allergens in untreated grass pollen allergic patients in Germany. Methods: Serum samples from 101 adults with grass pollen allergy were analyzed for specific IgE (sIgE) to 8 allergenic molecules from timothy grass pollen and to the 112 allergenic molecules included in the ISAC panel. The results for the multiplex and singleplex tests were subsequently analyzed statistically. Results: Comparison of sIgE to grass pollen allergens detected by ISAC 112 and the singleplex ImmunoCAP assay revealed the following correlation coefficients: 0.88 (rPhl p1), 0.96 (rPhl p2), 0.70 (nPhl p4), 0.94 (rPhl p5b), 0.92 (rPhl p6), 0.85 (rPhl p11), and 0.78 (rPhl p12). Conclusion: Molecular testing with ISAC 112 correlates well with the ImmunoCAP platform for respective molecular timothy grass pollen allergens.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
653 a Molecular allergy
653 a Multiplex
653 a ImmunoCAP
653 a ISAC
653 a Component-resolved diagnosis
700a Gutermuth, J.4 aut
700a Onell, A.4 aut
700a Borres, Magnus P.u Uppsala universitet,Pediatrik4 aut0 (Swepub:uu)magbo385
700a Schaeffner, I4 aut
700a Darsow, U.4 aut
700a Pfab, F.4 aut
700a Brockow, K.4 aut
700a Ring, J.4 aut
700a Behrendt, H.4 aut
700a Jakob, T.4 aut
700a Huss-Marp, J.4 aut
710a Uppsala universitetb Pediatrik4 org
773t Journal of investigational allergology & clinical immunologyg 25:3, s. 190-195q 25:3<190-195x 1018-9068x 1698-0808
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-262011

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