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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005895naa a2200829 4500
001oai:gup.ub.gu.se/312868
003SwePub
008240528s2021 | |||||||||||000 ||eng|
0247 a https://gup.ub.gu.se/publication/3128682 URI
0247 a https://doi.org/10.1136/bmjopen-2021-0576322 DOI
040 a (SwePub)gu
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Reyes, C.4 aut
2451 0a Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study
264 c 2021-12-22
264 1b BMJ,c 2021
520 a Objective To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. Design and setting This is a retrospective cohort study using 15 healthcare databases (primary and secondary electronic healthcare records, insurance and national claims data) from the USA, Europe and South Korea, standardised to the Observational Medical Outcomes Partnership common data model. Data were gathered from 1 March to 31 October 2020. Participants Two non-mutually exclusive cohorts were defined: (1) individuals diagnosed with COVID-19 (diagnosed cohort) and (2) individuals hospitalised with COVID-19 (hospitalised cohort), and stratified by hypertension status. Follow-up was from COVID-19 diagnosis/hospitalisation to death, end of the study period or 30 days. Outcomes Demographics, comorbidities and 30-day outcomes (hospitalisation and death for the 'diagnosed' cohort and adverse events and death for the 'hospitalised' cohort) were reported. Results We identified 2 851 035 diagnosed and 563 708 hospitalised patients with COVID-19. Hypertension was more prevalent in the latter (ranging across databases from 17.4% (95% CI 17.2 to 17.6) to 61.4% (95% CI 61.0 to 61.8) and from 25.6% (95% CI 24.6 to 26.6) to 85.9% (95% CI 85.2 to 86.6)). Patients in both cohorts with hypertension were predominantly >50 years old and female. Patients with hypertension were frequently diagnosed with obesity, heart disease, dyslipidaemia and diabetes. Compared with patients without hypertension, patients with hypertension in the COVID-19 diagnosed cohort had more hospitalisations (ranging from 1.3% (95% CI 0.4 to 2.2) to 41.1% (95% CI 39.5 to 42.7) vs from 1.4% (95% CI 0.9 to 1.9) to 15.9% (95% CI 14.9 to 16.9)) and increased mortality (ranging from 0.3% (95% CI 0.1 to 0.5) to 18.5% (95% CI 15.7 to 21.3) vs from 0.2% (95% CI 0.2 to 0.2) to 11.8% (95% CI 10.8 to 12.8)). Patients in the COVID-19 hospitalised cohort with hypertension were more likely to have acute respiratory distress syndrome (ranging from 0.1% (95% CI 0.0 to 0.2) to 65.6% (95% CI 62.5 to 68.7) vs from 0.1% (95% CI 0.0 to 0.2) to 54.7% (95% CI 50.5 to 58.9)), arrhythmia (ranging from 0.5% (95% CI 0.3 to 0.7) to 45.8% (95% CI 42.6 to 49.0) vs from 0.4% (95% CI 0.3 to 0.5) to 36.8% (95% CI 32.7 to 40.9)) and increased mortality (ranging from 1.8% (95% CI 0.4 to 3.2) to 25.1% (95% CI 23.0 to 27.2) vs from 0.7% (95% CI 0.5 to 0.9) to 10.9% (95% CI 10.4 to 11.4)) than patients without hypertension. Conclusions COVID-19 patients with hypertension were more likely to suffer severe outcomes, hospitalisations and deaths compared with those without hypertension.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicin0 (SwePub)3022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicine0 (SwePub)3022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
653 a COVID-19
653 a epidemiology
653 a hypertension
653 a coronavirus disease 2019
653 a mortality
653 a General & Internal Medicine
7001 a Pistillo, A.4 aut
7001 a Fernandez-Bertolin, S.4 aut
7001 a Recalde, M.4 aut
7001 a Roel, E.4 aut
7001 a Puente, D.4 aut
7001 a Sena, A. G.4 aut
7001 a Blacketer, C.4 aut
7001 a Lai, L. N.4 aut
7001 a Alshammari, T. M.4 aut
7001 a Ahmed, W. U. R.4 aut
7001 a Alser, O.4 aut
7001 a Alghoul, H.4 aut
7001 a Areia, C.4 aut
7001 a Dawoud, D.4 aut
7001 a Prats-Uribe, A.4 aut
7001 a Valveny, N.4 aut
7001 a de Maeztu, G.4 aut
7001 a Redo, L. S.4 aut
7001 a Roldan, J. M.4 aut
7001 a Montesinos, I. L.4 aut
7001 a Schilling, L. M.4 aut
7001 a Golozar, A.4 aut
7001 a Reich, C.4 aut
7001 a Posada, J. D.4 aut
7001 a Shah, N.4 aut
7001 a You, S. C.4 aut
7001 a Lynch, K. E.4 aut
7001 a DuVall, S. L.4 aut
7001 a Matheny, M. E.4 aut
7001 a Nyberg, Fredrik,d 1961u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xnybef
7001 a Ostropolets, A.4 aut
7001 a Hripcsak, G.4 aut
7001 a Rijnbeek, P. R.4 aut
7001 a Suchard, M. A.4 aut
7001 a Ryan, P.4 aut
7001 a Kostka, K.4 aut
7001 a Duarte-Salles, T.4 aut
7102 a Göteborgs universitetb Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa4 org
7730 t Bmj Opend : BMJg 11:12q 11:12x 2044-6055
8564 u https://bmjopen.bmj.com/content/bmjopen/11/12/e057632.full.pdf
8564 8u https://gup.ub.gu.se/publication/312868
8564 8u https://doi.org/10.1136/bmjopen-2021-057632

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