Sibling Alcohol Use Disorder Is Associated With Increased Risk for Suicide Attempt

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Fältnamn	Indikatorer	Metadata
000		03771naa a2200445 4500
001		oai:lup.lub.lu.se:31d05ac0-bf2e-4381-a745-2bcf0fdc2c83
003		SwePub
008		220308s2022 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://lup.lub.lu.se/record/31d05ac0-bf2e-4381-a745-2bcf0fdc2c832 URI
024	7	a https://doi.org/10.1177/216770262110250412 DOI
040		a (SwePub)lu
041		a engb eng
042		9 SwePub
072	7	a art2 swepub-publicationtype
072	7	a ref2 swepub-contenttype
100	1	a Stephenson, Mallory E.u Virginia Commonwealth University4 aut
245	1 0	a Sibling Alcohol Use Disorder Is Associated With Increased Risk for Suicide Attempt
264		c 2021-06-23
264	1	b SAGE Publications,c 2022
520		a The association between having a sibling diagnosed with alcohol use disorder (AUD) and risk for suicide attempt may be attributable to shared genetic liability between AUD and suicidal behavior, effects of environmental exposure to a sibling’s AUD, or both. To distinguish between these alternatives, we conducted a series of Cox regression models using data derived from Swedish population-based registers with national coverage. Among full sibling pairs (656,807 males and 607,096 females), we found that, even after we accounted for the proband’s AUD status, the proband’s risk for suicide attempt was significantly elevated when the proband’s sibling was affected by AUD. Furthermore, the proband’s risk for suicide attempt was consistently higher when the sibling’s AUD registration had occurred more recently. Our findings provide evidence for exposure to sibling AUD as an environmental risk factor for suicide attempt and suggest that clinical outreach may be warranted following a sibling’s diagnosis with AUD.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Beroendelära0 (SwePub)303092 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Substance Abuse0 (SwePub)303092 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653		a alcohol use disorder
653		a environmental risk factor
653		a sibling
653		a suicidal behavior
653		a suicide attempt
700	1	a Larsson Lönn, Sarau Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)mats-sla
700	1	a Salvatore, Jessica E.u Virginia Commonwealth University4 aut
700	1	a Sundquist, Janu Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-jsu
700	1	a Kendler, Kenneth S.u Virginia Commonwealth University4 aut0 (Swepub:lu)med-kek
700	1	a Sundquist, Kristinau Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-ksq
700	1	a Edwards, Alexis C.u Virginia Commonwealth University4 aut0 (Swepub:lu)al7546ed
710	2	a Virginia Commonwealth Universityb Allmänmedicin och klinisk epidemiologi4 org
773	0	t Clinical Psychological Scienced : SAGE Publicationsg 10:2, s. 374-382q 10:2<374-382x 2167-7026x 2167-7034
856	4	u http://dx.doi.org/10.1177/21677026211025041y FULLTEXT
856	4 8	u https://lup.lub.lu.se/record/31d05ac0-bf2e-4381-a745-2bcf0fdc2c83
856	4 8	u https://doi.org/10.1177/21677026211025041

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Av författaren/redakt...: Stephenson, Mall ...; Larsson Lönn, Sa ...; Salvatore, Jessi ...; Sundquist, Jan; Kendler, Kenneth ...; Sundquist, Krist ...; visa fler...; Edwards, Alexis ...; visa färre...

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