WFRF:(Shiga Taro)
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- Imamura, TeruhikoUniversity of Tokyo, Japan (author)
Bosentan improved persistent pulmonary hypertension in a case after implantation of a left ventricular assist device
- Article/chapterEnglish2013
Publisher, publication year, extent ...
- 2012-09-27
- Springer,2013
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:liu-111187
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-111187URI
- https://doi.org/10.1007/s10047-012-0662-4DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- No medical treatment has been established to ameliorate pulmonary hypertension (PH) due to left heart disease. Heart transplantation (HTx) is thus far the definitive therapy for stage D heart failure, but concomitant PH is one of the major risk factors for death after HTx. Recently, implantation of a left ventricular assist device (LVAD) has been reported to improve PH and has become a major bridge tool for HTx. We experienced a rare case with persistent PH even after the implantation of a continuous-flow LVAD. The administration of an endothelin receptor antagonist, bosentan, significantly decreased pulmonary vascular resistance. Combination therapy with LVAD implantation and anti-PH medication may be useful for patients with stage D heart failure complicated with severe PH.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences hsv//eng
- Out of proportion; Postcapillary; Endothelin receptor antagonist
Added entries (persons, corporate bodies, meetings, titles ...)
- Kinugawa, KoichiroUniversity of Tokyo, Japan (author)
- Hatano, MasaruUniversity of Tokyo, Japan (author)
- Kato, NaokoUniversity of Tokyo, Japan(Swepub:liu)naope77 (author)
- Minatsuki, ShunUniversity of Tokyo, Japan (author)
- Muraoka, HironoriUniversity of Tokyo, Japan (author)
- Inaba, ToshiroUniversity of Tokyo, Japan (author)
- Maki, HisatakaUniversity of Tokyo, Japan (author)
- Shiga, TaroUniversity of Tokyo, Japan (author)
- Yao, AtsushiUniversity of Tokyo, Japan (author)
- Kyo, ShuneiUniversity of Tokyo, Japan (author)
- Ono, MinoruUniversity of Tokyo, Japan (author)
- Nagai, RyozoJichi Medical University, Japan (author)
- University of Tokyo, JapanJichi Medical University, Japan (creator_code:org_t)
Related titles
- In:Journal of Artificial Organs: Springer16:1, s. 101-1041434-72291619-0904
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- Linköping University
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