Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Vodička Pavel) > Genome-wide associa...

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		06835naa a2201681 4500
001		oai:DiVA.org:umu-94549
003		SwePub
008		141013s2014 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-945492 URI
024	7	a https://doi.org/10.1038/ng.30522 DOI
040		a (SwePub)umu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Wolpin, Brian M.4 aut
245	1 0	a Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
264		c 2014-09-01
264	1	b Springer Science and Business Media LLC,c 2014
338		a print2 rdacarrier
520		a We performed a multistage genome-wide association study including 7,683 individuals with pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome-wide significance: rs6971499 at 7q32.3 (LINC-PINT, per-allele odds ratio (OR) = 0.79, 95% confidence interval (CI) 0.74-0.84, P = 3.0 x 10(-12)), rs7190458 at 16q23.1 (BCAR1/CTRB1/CTRB2, OR = 1.46, 95% CI 1.30-1.65, P = 1.1 x 10(-10)), rs9581943 at 13q12.2 (PDX1, OR = 1.15, 95% CI 1.10-1.20, P = 2.4 x 10(-9)) and rs16986825 at 22q12.1 (ZNRF3, OR = 1.18, 95% CI 1.12-1.25, P = 1.2 x 10(-8)). We identified an independent signal in exon 2 of TERT at the established region 5p15.33 (rs2736098, OR = 0.80, 95% CI 0.76-0.85, P = 9.8 x 10(-14)). We also identified a locus at 8q24.21 (rs1561927, P = 1.3 x 10(-7)) that approached genome-wide significance located 455 kb telomeric of PVT1. Our study identified multiple new susceptibility alleles for pancreatic cancer that are worthy of follow-up studies.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng
700	1	a Rizzato, Cosmeri4 aut
700	1	a Kraft, Peter4 aut
700	1	a Kooperberg, Charles4 aut
700	1	a Petersen, Gloria M.4 aut
700	1	a Wang, Zhaoming4 aut
700	1	a Arslan, Alan A.4 aut
700	1	a Beane-Freeman, Laura4 aut
700	1	a Bracci, Paige M.4 aut
700	1	a Buring, Julie4 aut
700	1	a Canzian, Federico4 aut
700	1	a Duell, Eric J.4 aut
700	1	a Gallinger, Steven4 aut
700	1	a Giles, Graham G.4 aut
700	1	a Goodman, Gary E.4 aut
700	1	a Goodman, Phyllis J.4 aut
700	1	a Jacobs, Eric J.4 aut
700	1	a Kamineni, Aruna4 aut
700	1	a Klein, Alison P.4 aut
700	1	a Kolonel, Laurence N.4 aut
700	1	a Kulke, Matthew H.4 aut
700	1	a Li, Donghui4 aut
700	1	a Malats, Nuria4 aut
700	1	a Olson, Sara H.4 aut
700	1	a Risch, Harvey A.4 aut
700	1	a Sesso, Howard D.4 aut
700	1	a Visvanathan, Kala4 aut
700	1	a White, Emily4 aut
700	1	a Zheng, Wei4 aut
700	1	a Abnet, Christian C.4 aut
700	1	a Albanes, Demetrius4 aut
700	1	a Andreotti, Gabriella4 aut
700	1	a Austin, Melissa A.4 aut
700	1	a Barfield, Richard4 aut
700	1	a Basso, Daniela4 aut
700	1	a Berndt, Sonja I.4 aut
700	1	a Boutron-Ruault, Marie-Christine4 aut
700	1	a Brotzman, Michelle4 aut
700	1	a Buechler, Markus W.4 aut
700	1	a Bueno-de-Mesquita, H. Bas4 aut
700	1	a Bugert, Peter4 aut
700	1	a Burdette, Laurie4 aut
700	1	a Campa, Daniele4 aut
700	1	a Caporaso, Neil E.4 aut
700	1	a Capurso, Gabriele4 aut
700	1	a Chung, Charles4 aut
700	1	a Cotterchio, Michelle4 aut
700	1	a Costello, Eithne4 aut
700	1	a Elena, Joanne4 aut
700	1	a Funel, Niccola4 aut
700	1	a Gaziano, J. Michael4 aut
700	1	a Giese, Nathalia A.4 aut
700	1	a Goggins, Michael4 aut
700	1	a Gorman, Megan J.4 aut
700	1	a Gross, Myron4 aut
700	1	a Haiman, Christopher A.4 aut
700	1	a Hassan, Manal4 aut
700	1	a Helzlsouer, Kathy J.4 aut
700	1	a Henderson, Brian E.4 aut
700	1	a Holly, Elizabeth A.4 aut
700	1	a Hu, Nan4 aut
700	1	a Hunter, David J.4 aut
700	1	a Innocenti, Federico4 aut
700	1	a Jenab, Mazda4 aut
700	1	a Kaaks, Rudolf4 aut
700	1	a Key, Timothy J.4 aut
700	1	a Khaw, Kay-Tee4 aut
700	1	a Klein, Eric A.4 aut
700	1	a Kogevinas, Manolis4 aut
700	1	a Krogh, Vittorio4 aut
700	1	a Kupcinskas, Juozas4 aut
700	1	a Kurtz, Robert C.4 aut
700	1	a LaCroix, Andrea4 aut
700	1	a Landi, Maria T.4 aut
700	1	a Landi, Stefano4 aut
700	1	a Le Marchand, Loic4 aut
700	1	a Mambrini, Andrea4 aut
700	1	a Mannisto, Satu4 aut
700	1	a Milne, Roger L.4 aut
700	1	a Nakamura, Yusuke4 aut
700	1	a Oberg, Ann L.4 aut
700	1	a Owzar, Kouros4 aut
700	1	a Patel, Alpa V.4 aut
700	1	a Peeters, Petra H. M.4 aut
700	1	a Peters, Ulrike4 aut
700	1	a Pezzilli, Raffaele4 aut
700	1	a Piepoli, Ada4 aut
700	1	a Porta, Miquel4 aut
700	1	a Real, Francisco X.4 aut
700	1	a Riboli, Elio4 aut
700	1	a Rothman, Nathaniel4 aut
700	1	a Scarpa, Aldo4 aut
700	1	a Shu, Xiao-Ou4 aut
700	1	a Silverman, Debra T.4 aut
700	1	a Soucek, Pavel4 aut
700	1	a Sund, Malinu Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap4 aut0 (Swepub:umu)masu0021
700	1	a Talar-Wojnarowska, Renata4 aut
700	1	a Taylor, Philip R.4 aut
700	1	a Theodoropoulos, George E.4 aut
700	1	a Thornquist, Mark4 aut
700	1	a Tjonneland, Anne4 aut
700	1	a Tobias, Geoffrey S.4 aut
700	1	a Trichopoulos, Dimitrios4 aut
700	1	a Vodicka, Pavel4 aut
700	1	a Wactawski-Wende, Jean4 aut
700	1	a Wentzensen, Nicolas4 aut
700	1	a Wu, Chen4 aut
700	1	a Yu, Herbert4 aut
700	1	a Yu, Kai4 aut
700	1	a Zeleniuch-Jacquotte, Anne4 aut
700	1	a Hoover, Robert4 aut
700	1	a Hartge, Patricia4 aut
700	1	a Fuchs, Charles4 aut
700	1	a Chanock, Stephen J.4 aut
700	1	a Stolzenberg-Solomon, Rachael S.4 aut
700	1	a Amundadottir, Laufey T.4 aut
710	2	a Umeå universitetb Institutionen för kirurgisk och perioperativ vetenskap4 org
773	0	t Nature Geneticsd : Springer Science and Business Media LLCg 46:9, s. 994-+q 46:9<994-+x 1061-4036x 1546-1718
856	4	u https://europepmc.org/articles/pmc4191666?pdf=render
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-94549
856	4 8	u https://doi.org/10.1038/ng.3052

Hitta via bibliotek

Nature Genetics (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Wolpin, Brian M.; Rizzato, Cosmeri; Kraft, Peter; Kooperberg, Char ...; Petersen, Gloria ...; Wang, Zhaoming; visa fler...; Arslan, Alan A.; Beane-Freeman, L ...; Bracci, Paige M.; Buring, Julie; Canzian, Federic ...; Duell, Eric J.; Gallinger, Steve ...; Giles, Graham G.; Goodman, Gary E.; Goodman, Phyllis ...; Jacobs, Eric J.; Kamineni, Aruna; Klein, Alison P.; Kolonel, Laurenc ...; Kulke, Matthew H ...; Li, Donghui; Malats, Nuria; Olson, Sara H.; Risch, Harvey A.; Sesso, Howard D.; Visvanathan, Kal ...; White, Emily; Zheng, Wei; Abnet, Christian ...; Albanes, Demetri ...; Andreotti, Gabri ...; Austin, Melissa ...; Barfield, Richar ...; Basso, Daniela; Berndt, Sonja I.; Boutron-Ruault, ...; Brotzman, Michel ...; Buechler, Markus ...; Bueno-de-Mesquit ...; Bugert, Peter; Burdette, Laurie; Campa, Daniele; Caporaso, Neil E ...; Capurso, Gabriel ...; Chung, Charles; Cotterchio, Mich ...; Costello, Eithne; Elena, Joanne; Funel, Niccola; Gaziano, J. Mich ...; Giese, Nathalia ...; Goggins, Michael; Gorman, Megan J.; Gross, Myron; Haiman, Christop ...; Hassan, Manal; Helzlsouer, Kath ...; Henderson, Brian ...; Holly, Elizabeth ...; Hu, Nan; Hunter, David J.; Innocenti, Feder ...; Jenab, Mazda; Kaaks, Rudolf; Key, Timothy J.; Khaw, Kay-Tee; Klein, Eric A.; Kogevinas, Manol ...; Krogh, Vittorio; Kupcinskas, Juoz ...; Kurtz, Robert C.; LaCroix, Andrea; Landi, Maria T.; Landi, Stefano; Le Marchand, Loi ...; Mambrini, Andrea; Mannisto, Satu; Milne, Roger L.; Nakamura, Yusuke; Oberg, Ann L.; Owzar, Kouros; Patel, Alpa V.; Peeters, Petra H ...; Peters, Ulrike; Pezzilli, Raffae ...; Piepoli, Ada; Porta, Miquel; Real, Francisco ...; Riboli, Elio; Rothman, Nathani ...; Scarpa, Aldo; Shu, Xiao-Ou; Silverman, Debra ...; Soucek, Pavel; Sund, Malin; Talar-Wojnarowsk ...; Taylor, Philip R ...; Theodoropoulos, ...; Thornquist, Mark; Tjonneland, Anne; Tobias, Geoffrey ...; Trichopoulos, Di ...; Vodicka, Pavel; Wactawski-Wende, ...; Wentzensen, Nico ...; Wu, Chen; Yu, Herbert; Yu, Kai; Zeleniuch-Jacquo ...; Hoover, Robert; Hartge, Patricia; Fuchs, Charles; Chanock, Stephen ...; Stolzenberg-Solo ...; Amundadottir, La ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinska och f ...; och Medicinsk geneti ...

Artiklar i publikationen: Nature Genetics

Av lärosätet: Umeå universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se