Regular moist snuff dipping does not affect endurance exercise performance

• Physiological and medical effects of snuff have previously been obtained either in cross-sectional studies or after snuff administration to non-tobacco users, but the effects of snuff cessation (SC) after several years of daily use on individual level are unknown. 24 participants with >2 years of daily snuff-use were tested before and after >6 weeks SC (SCG), together with a control group (CO) of 11 snuff users who kept their normal habits. Resting heart rate (HR) was significantly lower in SCG after SC. Body mass in SCG group increased by 1.4 ± 1.7 kg and blood pressure (BP) were reduced, but without significant differences between groups. Total cholesterol increased from 4.12 ± 0.54 (95% CI 3.89–4.35) to 4.46 ± 0.70 (95% CI 4.16–4.75) mM/L in SCG, due to increased LDL, and this change was significantly different from CO. Resting values of HDL, C-reactive protein, and free fatty acids (FFA) remained unchanged in both groups. During a four-stage incremental (from 50 to 80% of VO2max) and a prolonged (60 min at 50% of VO2max) cycling test HR and BP were reduced in SCG, while oxygen uptake (VO2), respiratory exchange ratio, blood lactate (bLa) and blood glucose (bGlu) concentration, and rate of perceived exertion were unchanged. All measurements were unchanged in CO. During the prolonged exercise FFA was reduced but there was no significant difference between groups. During the maximal treadmill running test peak values of VO2, pulmonary ventilation (VE), time to exhaustion and bLa were unchanged in both groups. In conclusion, endurance exercise performance (VO2max and maximal endurance time) does not seem to be affected by prolonged snuff use, while effects on cardiovascular risk factors are contradictory.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Physiology (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)

Keyword

Smokeless tobacco

Nicotine

Cardiovascular risk factors

Medicin/Teknik

Medicine/Technology

Publication and Content Type

ref (subject category)

kon (subject category)