Magnetic Resonance Imaging of the Heart: Image quality, measurement accuracy and patient experience

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Fältnamn	Indikatorer	Metadata
000		06757nam a2200601 4500
001		oai:DiVA.org:oru-77209
003		SwePub
008		191011s2016 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
009		oai:DiVA.org:liu-130796
020		a 9789176857427q print
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-772092 URI
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1307962 URI
024	7	a https://doi.org/10.3384/diss.diva-1307962 DOI
040		a (SwePub)orud (SwePub)liu
041		a engb eng
042		9 SwePub
072	7	a vet2 swepub-contenttype
072	7	a dok2 swepub-publicationtype
100	1	a Ahlander, Britt-Marie,d 1954-u Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten4 aut0 (Swepub:liu)briah72
245	1 0	a Magnetic Resonance Imaging of the Heart :b Image quality, measurement accuracy and patient experience
264	1	a Linköping :b Linköping University Electronic Press,c 2016
300		a 74 s.
338		a electronic2 rdacarrier
490	0	a Linköping University Medical Dissertations,x 0345-0082 ;v 1524
520		a Background: Non-invasive diagnostic imaging of atherosclerotic coronary artery disease (CAD) is frequently carried out with cardiovascular magnetic resonance imaging (CMR) or myocardial perfusion single photon emission computed tomography (MPS). CMR is the gold standard for the evaluation of scar after myocardial infarction and MPS the clinical gold standard for ischemia. Magnetic Resonance Imaging (MRI) is at times difficult for patients and may induce anxiety while patient experience of MPS is largely unknown.Aims: To evaluate image quality in CMR with respect to the sequences employed, the influence of atrial fibrillation, myocardial perfusion and the impact of patient information. Further, to study patient experience in relation to MRI with the goal of improving the care of these patients.Method: Four study designs have been used. In paper I, experimental cross-over, paper (II) experimental controlled clinical trial, paper (III) psychometric crosssectional study and paper (IV) prospective intervention study. A total of 475 patients ≥ 18 years with primarily cardiac problems (I-IV) except for those referred for MRI of the spine (III) were included in the four studies.Result: In patients (n=20) with atrial fibrillation, a single shot steady state free precession (SS-SSFP) sequence showed significantly better image quality than the standard segmented inversion recovery fast gradient echo (IR-FGRE) sequence (I). In first-pass perfusion imaging the gradient echo-echo planar imaging sequence (GREEPI) (n=30) had lower signal-to-noise and contrast–to-noise ratios than the steady state free precession sequence (SSFP) (n=30) but displayed a higher correlation with the MPS results, evaluated both qualitatively and quantitatively (II). The MRIAnxiety Questionnaire (MRI-AQ) was validated on patients, referred for MRI of either the spine (n=193) or the heart (n=54). The final instrument had 15 items divided in two factors regarding Anxiety and Relaxation. The instrument was found to have satisfactory psychometric properties (III). Patients who prior CMR viewed an information video scored significantly (lower) better in the factor Relaxation, than those who received standard information. Patients who underwent MPS scored lower on both factors, Anxiety and Relaxation. The extra video information had no effect on CMR image quality (IV).Conclusion: Single shot imaging in atrial fibrillation produced images with less artefact than a segmented sequence. In first-pass perfusion imaging, the sequence GRE-EPI was superior to SSFP. A questionnaire depicting anxiety during MRI showed that video information prior to imaging helped patients relax but did not result in an improvement in image quality.
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Radiologi och bildbehandling0 (SwePub)302082 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Radiology, Nuclear Medicine and Medical Imaging0 (SwePub)302082 hsv//eng
650	7	a TEKNIK OCH TEKNOLOGIERx Medicinteknikx Medicinsk bildbehandling0 (SwePub)206032 hsv//swe
650	7	a ENGINEERING AND TECHNOLOGYx Medical Engineeringx Medical Image Processing0 (SwePub)206032 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650	7	a TEKNIK OCH TEKNOLOGIERx Medicinteknikx Medicinsk laboratorie- och mätteknik0 (SwePub)206012 hsv//swe
650	7	a ENGINEERING AND TECHNOLOGYx Medical Engineeringx Medical Laboratory and Measurements Technologies0 (SwePub)206012 hsv//eng
650	7	a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe
650	7	a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng
653		a Medicine
653		a Medicin
700	1	a Engvall, Jan,c Professoru Linköpings universitet,Avdelningen för kardiovaskulär medicin,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US4 ths0 (Swepub:liu)janen74
700	1	a Ericsson, Elisabeth,c docent,d 1959-u Örebro universitet, Institutionen för hälsovetenskaper,Institutionen för hälsovetenskaper, Örebro universitet4 ths0 (Swepub:liu)elier72
700	1	a Maret, Eva,c Med. Dr.u Institutionen för laboratoriemedicin, Karolinska institutet, Stockholm4 ths
700	1	a Carlsson, Marcus,c Docentu Klinisk Fysiologi, Skånes Universitetssjukhus, Lund4 opn
710	2	a Linköpings universitetb Avdelningen för kardiovaskulär medicin4 org
856	4	u https://doi.org/10.3384/diss.diva-130796y Fulltext
856	4	u http://liu.diva-portal.org/smash/get/diva2:955033/PREVIEW01.jpgy preview image
856	4	u https://oru.diva-portal.org/smash/get/diva2:1360330/FULLTEXT01.pdfx primaryx Raw objecty fulltext
856	4	u https://oru.diva-portal.org/smash/get/diva2:1360330/COVER01.pdfy cover
856	4	u https://liu.diva-portal.org/smash/get/diva2:955033/FULLTEXT01.pdfx primaryx Raw objecty fulltext
856	4	u https://liu.diva-portal.org/smash/get/diva2:955033/COVER01.pdfy cover
856	4	u https://liu.diva-portal.org/smash/get/diva2:955033/PREVIEW01.jpgx Previewy preview image
856	4	u http://liu.diva-portal.org/smash/get/diva2:955033/FULLTEXT01
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-77209
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-130796
856	4 8	u https://doi.org/10.3384/diss.diva-130796

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