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Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms.
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- Lagging, Martin, 1965 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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- Askarieh, Galia, 1983 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
- Negro, Francesco (author)
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- Bibert, Stephanie (author)
- Missale, Gabriele (author)
- Ferrari, Carlo (author)
- Neumann, Avidan U (author)
- Pawlotsky, Jean-Michel (author)
- Haagmans, Bart L (author)
- Zeuzem, Stefan (author)
- Bochud, Pierre-Yves (author)
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- (creator_code:org_t)
- 2011-02-24
- 2011
- English.
- In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 6:2
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C. Several recent studies report that single nucleotide polymorphisms (SNPs) adjacent to IL28B predict spontaneous resolution of HCV infection and outcome of treatment among HCV genotype 1 infected patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Keyword
- Adult
- Antiviral Agents
- administration & dosage
- therapeutic use
- Biomarkers
- Pharmacological
- analysis
- metabolism
- Chemokine CXCL10
- analysis
- genetics
- metabolism
- Drug Administration Schedule
- Female
- Hepatitis C
- Chronic
- diagnosis
- drug therapy
- genetics
- Humans
- Interferon-alpha
- administration & dosage
- therapeutic use
- Interleukins
- analysis
- genetics
- metabolism
- Male
- Middle Aged
- Pharmacogenetics
- Polymorphism
- Single Nucleotide
- physiology
- Prognosis
- RNA
- Viral
- analysis
- genetics
- Recombinant Proteins
Publication and Content Type
- ref (subject category)
- art (subject category)
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